Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells

Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 "Don't Eat Me" Signals

(2015) M. N. McCracken et al.   CLINICAL CANCER RESEARCH

Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages

(2015) Zhiyuan Lv et al.   JOURNAL OF IMMUNOLOGY

Macrophages are critical effectors of antibody therapies for cancer

(2015) Kipp Weiskopf et al.   mAbs

Effect of Polypurine Reverse Hoogsteen Hairpins on Relevant Cancer Target Genes in Different Human Cell Lines

(2015) Xenia Villalobos et al.   Nucleic Acid Therapeutics

NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages

(2015) Min-gu Song et al.   PLoS One

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

(2015) Jie Liu et al.   PLoS One

Sustained stabilization of Interleukin-8 mRNA in human macrophages

(2014) Linah Mahmoud et al.   RNA Biology

Effect of Culture Conditions on the Phenotype of THP-1 Monocyte Cell Line

(2013) Paulomi B. Aldo et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Polypurine reverse Hoogsteen hairpins as a gene therapy tool against survivin in human prostate cancer PC3 cells in vitro and in vivo

(2013) Laura Rodríguez et al.   BIOCHEMICAL PHARMACOLOGY

Stability and Immunogenicity Properties of the Gene-Silencing Polypurine Reverse Hoogsteen Hairpins

(2013) Xenia Villalobos et al.   MOLECULAR PHARMACEUTICS

The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications

(2012) Mark P Chao et al.   CURRENT OPINION IN IMMUNOLOGY

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2012) S. B. Willingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelial-dependent vasorelaxation

(2010) Eileen M. Bauer et al.   CARDIOVASCULAR RESEARCH

Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma

(2010) Mark P. Chao et al.   CELL

Coding Polypurine Hairpins Cause Target-Induced Cell Death in Breast Cancer Cells

(2010) M. Cristina de Almagro et al.   HUMAN GENE THERAPY

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

(2009) Siddhartha Jaiswal et al.   CELL

Polypurine Hairpins Directed against the Template Strand of DNA Knock Down the Expression of Mammalian Genes

(2009) M. Cristina de Almagro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Silencing of CD47 and Antibody Ligation of Thrombospondin-1 Enhance Ischemic Tissue Survival in a Porcine Model

(2008) Jeff S. Isenberg et al.   ANNALS OF SURGERY

Enhancing Cardiovascular Dynamics by Inhibition of Thrombospondin- 1/CD47 Signaling

(2008) Jeff Isenberg et al.   CURRENT DRUG TARGETS

Inhibition of “self” engulfment through deactivation of myosin-II at the phagocytic synapse between human cells

(2008) Richard K. Tsai et al.   JOURNAL OF CELL BIOLOGY