D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway

Lysosomal regulation of extracellular vesicle excretion during d-ribose-induced NLRP3 inflammasome activation in podocytes

(2019) Jinni Hong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Long-term administration of advanced glycation end-product stimulates the activation of NLRP3 inflammasome and sparking the development of renal injury

(2017) Wan-Ju Yeh et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Activation of NLRP3 Inflammasome by Advanced Glycation End Products Promotes Pancreatic Islet Damage

(2017) Xiang Kong et al.   Oxidative Medicine and Cellular Longevity

Alagebrium attenuates methylglyoxal induced oxidative stress and AGE formation in H9C2 cardiac myocytes

(2016) Arti Dhar et al.   LIFE SCIENCES

Quantitative assessment of organ distribution of dietary protein-bound13C-labeled Nɛ-carboxymethyllysine after a chronic oral exposure in mice

(2016) Frédéric J. Tessier et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gavage of D-Ribose induces Aβ-like deposits, Tau hyperphosphorylation as well as memory loss and anxiety-like behavior in mice

(2015) Beibei Wu et al.   Oncotarget

NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia

(2015) Pan Gao et al.   Journal of Diabetes Research

Nod-like Receptor Protein 3 (NLRP3) Inflammasome Activation and Podocyte Injury via Thioredoxin-Interacting Protein (TXNIP) during Hyperhomocysteinemia

(2014) Justine M. Abais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke

(2014) Fan Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation

(2014) C Han et al.   Cell Death & Disease

Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia

(2013) Justine M. Abais et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammasomes: sensors of metabolic stresses for vascular inflammation 

(2013) Xiao-feng Yang   Frontiers in Bioscience-Landmark

Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation

(2013) Pieter J. Bakker et al.   KIDNEY INTERNATIONAL

NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli During Hyperhomocysteinemia

(2012) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

d-ribose in glycation and protein aggregation

(2012) Yan Wei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

(2012) Hye-Mi Lee et al.   DIABETES

Activation of Nod-Like Receptor Protein 3 Inflammasomes Turns on Podocyte Injury and Glomerular Sclerosis in Hyperhomocysteinemia

(2012) Chun Zhang et al.   HYPERTENSION

d-Ribose glycates β2-microglobulin to form aggregates with high cytotoxicity through a ROS-mediated pathway

(2011) Fan-Lou Kong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

D-Ribose Induces Cellular Protein Glycation and Impairs Mouse Spatial Cognition

(2011) Chanshuai Han et al.   PLoS One

Endothelial FGF receptor signaling accelerates atherosclerosis

(2010) Jishan Che et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autoimmune kidney diseases

(2009) Mårten Segelmark et al.   AUTOIMMUNITY REVIEWS

Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells

(2009) Yan Wei et al.   BMC CELL BIOLOGY

The Role of Ribose on Oxidative Stress During Hypoxic Exercise: A Pilot Study

(2009) John G. Seifert et al.   JOURNAL OF MEDICINAL FOOD