GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease

Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer’s Disease

(2019) Jangampalli Pradeepkiran et al.   Cells

Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/β-Catenin Signaling Pathway in Glioma Cells

(2019) Cheng-Wei Chu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ApoE4: an emerging therapeutic target for Alzheimer’s disease

(2019) Mirna Safieh et al.   BMC Medicine

The origin of GSKIP, a multifaceted regulatory factor in the mammalian Wnt pathway

(2018) Chia-Hua Chou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel synthetic chalcone-coumarin hybrid for Aβ aggregation reduction, antioxidation, and neuroprotection

(2018) Shin-Ying Lee et al.   CNS Neuroscience & Therapeutics

Modeling Alzheimer’s Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation

(2018) Kuo-Hsuan Chang et al.   MOLECULAR NEUROBIOLOGY

Protein Phosphorylation is a Key Mechanism in Alzheimer’s Disease

(2017) Joana Oliveira et al.   JOURNAL OF ALZHEIMERS DISEASE

Interactions between Tau and Different Conformations of Tubulin: Implications for Tau Function and Mechanism

(2017) Aranda R. Duan et al.   JOURNAL OF MOLECULAR BIOLOGY

APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases

(2017) Hélène-Marie Lanoiselée et al.   PLOS MEDICINE

Increased Total TAU But Not Amyloid-β42; in Cerebrospinal Fluid Correlates with Short-Term Memory Impairment in Alzheimer's Disease

(2017) Yuh-Te Lin et al.   JOURNAL OF ALZHEIMERS DISEASE

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β

(2016) Alessandro Dema et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of PPARγ in endothelial cells leads to impaired angiogenesis

(2016) Sanna Vattulainen-Collanus et al.   JOURNAL OF CELL SCIENCE

Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells

(2016) Alison E. Mungenast et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Tau Structures

(2016) Jesus Avila et al.   Frontiers in Aging Neuroscience

GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis signaling in the regulation of mitochondrial elongation

(2015) Joon-Khim Loh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice

(2015) Veronika Anita Deák et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies

(2015) Joseph Saliba et al.   NATURE GENETICS

Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production

(2014) Yen-Chen Lin et al.   JOURNAL OF NEUROCHEMISTRY

cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex

(2014) Becky C. Carlyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease

(2013) M. E. Seward et al.   JOURNAL OF CELL SCIENCE

A novel APP mutation (D678H) in a Taiwanese patient exhibiting dementia and cerebral microvasculopathy

(2013) Min-Yu Lan et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Tau protein kinases: Involvement in Alzheimer's disease

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Prediction of the binding mode between GSK3β and a peptide derived from GSKIP using molecular dynamics simulation

(2011) Xu-Nan Tang et al.   BIOPOLYMERS

Human Pompe disease-induced pluripotent stem cells for pathogenesis modeling, drug testing and disease marker identification

(2011) Hsiang-Po Huang et al.   HUMAN MOLECULAR GENETICS

Protein kinase A phosphorylation of tau-serine 214 reorganizes microtubules and disrupts the endothelial cell barrier

(2010) Bing Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia

(2010) Jonathan Wills et al.   EXPERIMENTAL NEUROLOGY

Causes versus effects: the increasing complexities of Alzheimer’s disease pathogenesis

(2010) Siddhartha Mondragón-Rodríguez et al.   Expert Review of Neurotherapeutics

Glycogen synthase kinase-3β, or a link between amyloid and tau pathology?

(2010) D. Muyllaert et al.   GENES BRAIN AND BEHAVIOR

GSK3: A possible link between beta amyloid peptide and tau protein

(2009) Félix Hernández et al.   EXPERIMENTAL NEUROLOGY

Senescence impairs successful reprogramming to pluripotent stem cells

(2009) A. Banito et al.   GENES & DEVELOPMENT

Glycogen Synthase Kinase 3β Interaction Protein Functions as an A-kinase Anchoring Protein

(2009) Christian Hundsrucker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GSKIP, an inhibitor of GSK3β, mediates the N-cadherin/β-catenin pool in the differentiation of SH-SY5Y cells

(2009) Ching-Chih Lin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases

(2009) Yang Yu et al.   JOURNAL OF NEUROCHEMISTRY

Involvement of the residues of GSKIP, AxinGID, and FRATtide in their binding with GSK3β to unravel a novel C-terminal scaffold-binding region

(2009) Shen-Long Howng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

The Natively Unfolded Character of Tau and Its Aggregation to Alzheimer-like Paired Helical Filaments†

(2008) Sadasivam Jeganathan et al.   BIOCHEMISTRY

Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

(2008) Nicolas Sergeant et al.   Expert Review of Proteomics

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

(2008) Fei Liu et al.   FASEB JOURNAL

Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease

(2008) Siddhartha Mondragón-Rodríguez et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY