Drug repositioning for non-small cell lung cancer by using machine learning algorithms and topological graph theory

Network-based prediction and knowledge mining of disease genes

(2015) Matthew B Carson et al.   BMC Medical Genomics

Nucleotide metabolism, oncogene-induced senescence and cancer

(2015) Katherine M. Aird et al.   CANCER LETTERS

Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

(2015) Naoomi Tominaga et al.   Nature Communications

Prioritizing Therapeutics for Lung Cancer: An Integrative Meta-analysis of Cancer Gene Signatures and Chemogenomic Data

(2015) Kristen Fortney et al.   PLoS Computational Biology

Proton Beam Therapy for Non-Small Cell Lung Cancer: Current Clinical Evidence and Future Directions

(2015) Abigail Berman et al.   Cancers

SNPdryad: predicting deleterious non-synonymous human SNPs using only orthologous protein sequences

(2014) Ka-Chun Wong et al.   BIOINFORMATICS

DNA replication stress: Causes, resolution and disease

(2014) Abdelghani Mazouzi et al.   EXPERIMENTAL CELL RESEARCH

In silico identification of potential targets and drugs for non-small cell lung cancer

(2014) Chien-Hung Huang et al.   IET Systems Biology

MutationTaster2: mutation prediction for the deep-sequencing age

(2014) Jana Marie Schwarz et al.   NATURE METHODS

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer

(2014) Agnes Stachnik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in MurinePseudomonasPneumonia

(2013) Khalilah L. Gates et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Computational Drug Repositioning: From Data to Therapeutics

(2013) M R Hurle et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Improving protein complex classification accuracy using amino acid composition profile

(2013) Chien-Hung Huang et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Prediction of microRNA-regulated protein interaction pathways in Arabidopsis using machine learning algorithms

(2013) Nilubon Kurubanjerdjit et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Tumor glycolysis as a target for cancer therapy: progress and prospects

(2013) Shanmugasundaram Ganapathy-Kanniappan et al.   Molecular Cancer

DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data

(2012) Clare Pacini et al.   BIOINFORMATICS

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug

(2012) Hee Lee et al.   BMC Systems Biology

Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade

(2012) Tong-You W. Wei et al.   CANCER SCIENCE

Cyclic GMP/protein kinase G type-Iα (PKG-Iα) signaling pathway promotes CREB phosphorylation and maintains higher c-IAP1, livin, survivin, and Mcl-1 expression and the inhibition of PKG-Iα kinase activity synergizes with cisplatin in non-small cell lung c

(2012) Janica C. Wong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Recycling side-effects into clinical markers for drug repositioning

(2012) Miquel Duran-Frigola et al.   Genome Medicine

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

(2012) Feixiong Cheng et al.   PLoS Computational Biology

Apoptosis in cancer: from pathogenesis to treatment

(2011) Rebecca SY Wong   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease

(2011) J. T. Dudley et al.   Science Translational Medicine

Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data

(2011) M. Sirota et al.   Science Translational Medicine

Identification of a Novel Biomarker, SEMA5A, for Non-Small Cell Lung Carcinoma in Nonsmoking Women

(2010) T.-P. Lu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The platelet contribution to cancer progression

(2010) N. M. BAMBACE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Reactome: a database of reactions, pathways and biological processes

(2010) D. Croft et al.   NUCLEIC ACIDS RESEARCH

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Evaluation of Drug–Disease Relationships to Identify Leads for Novel Drug Uses

(2009) A P Chiang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Causes and Consequences of Increased Glucose Metabolism of Cancers

(2008) R. J. Gillies et al.   JOURNAL OF NUCLEAR MEDICINE

ConsensusPathDB—a database for integrating human functional interaction networks

(2008) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH

Drug Target Identification Using Side-Effect Similarity

(2008) M. Campillos et al.   SCIENCE

Endocytosis and Cancer: an ‘Insider’ Network with Dangerous Liaisons

(2008) Letizia Lanzetti et al.   TRAFFIC