Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA

Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion

(2018) James Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane protein insertion through a mitochondrial β-barrel gate

(2018) Alexandra I. C. Höhr et al.   SCIENCE

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding

(2017) Bob Schiffrin et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery

(2017) Rebecca S. Bamert et al.   MOLECULAR MICROBIOLOGY

Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop

(2017) Joseph S. Wzorek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of outer membrane protein insertion by the BAM complex

(2016) Yinghong Gu et al.   NATURE

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of a stalled complex on the β-barrel assembly machine

(2016) James Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of the  -barrel assembly machinery complex

(2016) J. Bakelar et al.   SCIENCE

The GroEL–GroES Chaperonin Machine: A Nano-Cage for Protein Folding

(2016) Manajit Hayer-Hartl et al.   TRENDS IN BIOCHEMICAL SCIENCES

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

(2016) Matthew G. Iadanza et al.   Nature Communications

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

BamA Alone Accelerates Outer Membrane Protein Folding In Vitro through a Catalytic Mechanism

(2015) Ashlee M. Plummer et al.   BIOCHEMISTRY

Inhibition of the β-barrel assembly machine by a peptide that binds BamD

(2015) Christine L. Hagan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detecting Envelope Stress by Monitoring β-Barrel Assembly

(2014) Seung-Hyun Cho et al.   CELL

Structural basis for outer membrane lipopolysaccharide insertion

(2014) Haohao Dong et al.   NATURE

Structural basis for lipopolysaccharide insertion in the bacterial outer membrane

(2014) Shuai Qiao et al.   NATURE

Outer membrane  -barrel protein folding is physically controlled by periplasmic lipid head groups and BamA

(2014) D. Gessmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral Opening and Exit Pore Formation Are Required for BamA Function

(2014) Nicholas Noinaj et al.   STRUCTURE

Reconstitution of bacterial autotransporter assembly using purified components

(2014) Giselle Roman-Hernandez et al.   eLife

A comprehensive analysis of the Omp85/TpsB protein superfamily structural diversity, taxonomic occurrence, and evolution

(2014) Eva Heinz et al.   Frontiers in Microbiology

The Lipid Bilayer-Inserted Membrane Protein BamA of Escherichia coli Facilitates Insertion and Folding of Outer Membrane Protein A from Its Complex with Skp

(2013) Geetika J. Patel et al.   BIOCHEMISTRY

Bam Lipoproteins Assemble BamA in Vitro

(2013) Christine L. Hagan et al.   BIOCHEMISTRY

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

Protease homolog BepA (YfgC) promotes assembly and degradation of  -barrel membrane proteins in Escherichia coli

(2013) S.-i. Narita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic link between   barrel assembly and the initiation of autotransporter secretion

(2013) O. Pavlova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved Residues of the Putative L6 Loop of Escherichia coli BamA Play a Critical Role in the Assembly of  -Barrel Outer Membrane Proteins, Including That of BamA Itself

(2012) M. Leonard-Rivera et al.   JOURNAL OF BACTERIOLOGY

Activation of the Escherichia coli  -barrel assembly machine (Bam) is required for essential components to interact properly with substrate

(2012) D. P. Ricci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disulfide Rearrangement Triggered by Translocon Assembly Controls Lipopolysaccharide Export

(2012) S.-S. Chng et al.   SCIENCE

Evolution of the β-barrel assembly machinery

(2012) Chaille T. Webb et al.   TRENDS IN MICROBIOLOGY

The ReconstitutedEscherichia coliBam Complex Catalyzes Multiple Rounds of β-Barrel Assembly

(2011) Christine L. Hagan et al.   BIOCHEMISTRY

The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel

(2011) E. Freinkman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential and spatially restricted interactions of assembly factors with an autotransporter   domain

(2011) R. Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily

(2010) Anne-Sophie Delattre et al.   FEBS Journal

Dissection of β-barrel outer membrane protein assembly pathways through characterizing BamA POTRA 1 mutants of Escherichia coli

(2010) Drew Bennion et al.   MOLECULAR MICROBIOLOGY

Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane

(2010) S.-S. Chng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonconsecutive disulfide bond formation in an essential integral outer membrane protein

(2010) N. Ruiz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of Outer Membrane Protein Assembly from Purified Components

(2010) C. L. Hagan et al.   SCIENCE

Interaction of an autotransporter passenger domain with BamA during its translocation across the bacterial outer membrane

(2009) Raffaele Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding

(2009) Arthur L. Horwich et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins

(2008) Stephan Kutik et al.   CELL