Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides
出版年份 2019 全文链接
标题
Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides
作者
关键词
-
出版物
Scientific Reports
Volume 9, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-10
DOI
10.1038/s41598-019-49385-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Intracerebroventricular Administration of a 2′-O-Methyl Phosphorothioate Antisense Oligonucleotide Results in Activation of the Innate Immune System in Mouse Brain
- (2018) Lodewijk J.A. Toonen et al. Nucleic Acid Therapeutics
- Roles of endoplasmic reticulum stress and autophagy on H2O2‑induced oxidative stress injury in HepG2 cells
- (2018) Zhiming Wu et al. Molecular Medicine Reports
- Modulation of nuclear REST by alternative splicing: a potential therapeutic target for Huntington's disease
- (2017) Guo-Lin Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- FDA-Approved Oligonucleotide Therapies in 2017
- (2017) Cy A. Stein et al. MOLECULAR THERAPY
- Natalizumab-associated PML
- (2017) Nicholas Schwab et al. NEUROLOGY
- Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis
- (2017) Madhuri Chakravarthy et al. Scientific Reports
- Clinical safety of eteplirsen, a phosphorodiamidate morpholino oligomer (PMO), in Duchenne muscular dystrophy (DMD) patients amenable to skipping exon 51 of the DMD gene
- (2016) J. Mendell et al. NEUROMUSCULAR DISORDERS
- Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators
- (2015) Ulrike Flierl et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Leukocyte integrins: Role in leukocyte recruitment and as therapeutic targets in inflammatory disease
- (2015) Ioannis Mitroulis et al. PHARMACOLOGY & THERAPEUTICS
- CD49d is a disease progression biomarker and a potential target for immunotherapy in Duchenne muscular dystrophy
- (2015) Fernanda Pinto-Mariz et al. Skeletal Muscle
- Natalizumab Significantly Improves Cognitive Impairment over Three Years in MS: Pattern of Disability Progression and Preliminary MRI Findings
- (2015) Flavia Mattioli et al. PLoS One
- Therapeutic uses of anti- 4-integrin (anti-VLA-4) antibodies in multiple sclerosis
- (2014) N. Schwab et al. INTERNATIONAL IMMUNOLOGY
- Specific Phosphorylations Transmit Signals from Leukocyte β2to β1Integrins and Regulate Adhesion
- (2014) Liisa M. Uotila et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD49d antisense drug ATL1102 reduces disease activity in patients with relapsing-remitting MS
- (2014) V. Limmroth et al. NEUROLOGY
- Antisense Oligonucleotide Induction of Progerin in Human Myogenic Cells
- (2014) Yue-Bei Luo et al. PLoS One
- Antisense Oligonucleotide Therapies
- (2014) Kendall S. Frazier TOXICOLOGIC PATHOLOGY
- Transcriptional Profiling of Human Monocytes Identifies the Inhibitory Receptor CD300a as Regulator of Transendothelial Migration
- (2013) Sharang Ghavampour et al. PLoS One
- Clinical relevance of serum natalizumab concentration and anti-natalizumab antibodies in multiple sclerosis
- (2012) Anke Vennegoor et al. Multiple Sclerosis Journal
- Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching
- (2011) Clayton T Fragall et al. BMC Medical Genetics
- Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
- (2011) Cris S Constantinescu et al. BRITISH JOURNAL OF PHARMACOLOGY
- RNA Splicing Manipulation: Strategies to Modify Gene Expression for a Variety of Therapeutic Outcomes
- (2011) Steve D. Wilton et al. CURRENT GENE THERAPY
- Role for tumor necrosis factor-alpha in JC virus reactivation and progressive multifocal leukoencephalopathy
- (2010) Hassen S. Wollebo et al. JOURNAL OF NEUROIMMUNOLOGY
- SpliceAid: a database of experimental RNA target motifs bound by splicing proteins in humans
- (2009) F. Piva et al. BIOINFORMATICS
- Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo
- (2009) Aran F Labrijn et al. NATURE BIOTECHNOLOGY
- Human Splicing Finder: an online bioinformatics tool to predict splicing signals
- (2009) François-Olivier Desmet et al. NUCLEIC ACIDS RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now