标题
Engineering dendritic cell vaccines to improve cancer immunotherapy
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-27
DOI
10.1038/s41467-019-13368-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Enhancing Dendritic cell Therapy in Solid Tumors with Immune Modulating Conventional Treatment
- (2019) R.A. Belderbos et al. Molecular Therapy-Oncolytics
- Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells
- (2019) Dali Han et al. NATURE
- Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity
- (2019) Mikhail Binnewies et al. CELL
- Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy
- (2019) Melvyn T. Chow et al. IMMUNITY
- Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species
- (2019) Rapolas Zilionis et al. IMMUNITY
- Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation
- (2019) Huamin Wang et al. Nature Communications
- Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen
- (2019) Stefanie K. Wculek et al. Journal for ImmunoTherapy of Cancer
- The orphan nuclear receptor NR4A3 controls the differentiation of monocyte-derived dendritic cells following microbial stimulation
- (2019) Salix Boulet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Personalized Dendritic Cell Vaccines—Recent Breakthroughs and Encouraging Clinical Results
- (2019) Beatris Mastelic-Gavillet et al. Frontiers in Immunology
- TIM-3 Regulates CD103 + Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
- (2018) Álvaro de Mingo Pulido et al. CANCER CELL
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- Human dendritic cell subsets: an update
- (2018) Matthew Collin et al. IMMUNOLOGY
- Activation of human CD141+ and CD1c+ dendritic cells in vivo with combined TLR3 and TLR7/8 ligation
- (2018) Frances E Pearson et al. IMMUNOLOGY AND CELL BIOLOGY
- Plasmacytoid dendritic cell in immunity and cancer
- (2018) Dana Mitchell et al. JOURNAL OF NEUROIMMUNOLOGY
- A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments
- (2018) Kevin C. Barry et al. NATURE MEDICINE
- EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens
- (2018) Mario Leonardo Squadrito et al. NATURE METHODS
- Chimeric Antigen Receptor Therapy
- (2018) Carl H. June et al. NEW ENGLAND JOURNAL OF MEDICINE
- Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer
- (2018) Janos L. Tanyi et al. Science Translational Medicine
- Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance
- (2018) Melissa A. Meyer et al. Nature Communications
- Compromised functionality of monocyte-derived dendritic cells in multiple myeloma patients may limit their use in cancer immunotherapy
- (2018) Prajakta Shinde et al. Scientific Reports
- Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells
- (2018) Margaret E. Kirkling et al. Cell Reports
- Towards superior dendritic-cell vaccines for cancer therapy
- (2018) Mansi Saxena et al. Nature Biomedical Engineering
- Immune Adjuvant Targeting Micelles Allow Efficient Dendritic Cell Migration to Lymph Nodes for Enhanced Cellular Immunity
- (2018) Xiqin Yang et al. ACS Applied Materials & Interfaces
- Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function
- (2018) A. Laustsen et al. Nature Communications
- Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity
- (2018) Sreekumar Balan et al. Cell Reports
- Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
- (2018) Christopher S. Garris et al. IMMUNITY
- WDFY4 is required for cross-presentation in response to viral and tumor antigens
- (2018) Derek J. Theisen et al. SCIENCE
- Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?
- (2018) Anne Huber et al. Frontiers in Immunology
- CD8 + T Cells Orchestrate pDC-XCR1 + Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming
- (2017) Anna Brewitz et al. IMMUNITY
- Spatially restricted JAG1-Notch signaling in human thymus provides suitable DC developmental niches
- (2017) Enrique Martín-Gayo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity
- (2017) Andrés Alloatti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Oncolytic virus-induced cell death and immunity: a match made in heaven?
- (2017) Jolien De Munck et al. JOURNAL OF LEUKOCYTE BIOLOGY
- A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation
- (2017) S. Julia Wu et al. Cell Reports
- Critical Role for CD103 + /CD141 + Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma
- (2016) Edward W. Roberts et al. CANCER CELL
- Dendritic Cell Vaccination Enhances Immune Responses and Induces Regression of HER2 pos DCIS Independent of Route: Results of Randomized Selection Design Trial
- (2016) Lea Lowenfeld et al. CLINICAL CANCER RESEARCH
- Expansion and Activation of CD103 + Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition
- (2016) Hélène Salmon et al. IMMUNITY
- Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
- (2016) Christina Pfirschke et al. IMMUNITY
- Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma
- (2016) Sofie Wilgenhof et al. JOURNAL OF CLINICAL ONCOLOGY
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity
- (2016) Caroline Baer et al. NATURE CELL BIOLOGY
- The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
- (2016) Damya Laoui et al. Nature Communications
- Distinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic Cells
- (2016) Carlos G. Briseño et al. Cell Reports
- microRNA-155 deficiency impairs dendritic cell function in breast cancer
- (2016) Junfeng Wang et al. OncoImmunology
- Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells
- (2015) G. Schreibelt et al. CLINICAL CANCER RESEARCH
- The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome
- (2015) Cleo Goyvaerts et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Lentivirus-induced ‘Smart’ dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma
- (2015) B S Sundarasetty et al. GENE THERAPY
- GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells
- (2015) Julie Helft et al. IMMUNITY
- Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow
- (2015) Jaeyop Lee et al. JOURNAL OF EXPERIMENTAL MEDICINE
- miR-155 Upregulation in Dendritic Cells Is Sufficient To Break Tolerance In Vivo by Negatively Regulating SHIP1
- (2015) Evan F. Lind et al. JOURNAL OF IMMUNOLOGY
- A Phase I Clinical Trial of CD1c (BDCA-1)+ Dendritic Cells Pulsed With HLA-A*0201 Peptides for Immunotherapy of Metastatic Hormone Refractory Prostate Cancer
- (2015) Rebecca L. Prue et al. JOURNAL OF IMMUNOTHERAPY
- Batf3 maintains autoactivation of Irf8 for commitment of a CD8α+ conventional DC clonogenic progenitor
- (2015) Gary E Grajales-Reyes et al. NATURE IMMUNOLOGY
- The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathways
- (2015) Mohammad Samie et al. NATURE IMMUNOLOGY
- Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells
- (2015) A. R. Sanchez-Paulete et al. Cancer Discovery
- Selective and efficient generation of functional Batf3-dependent CD103+ dendritic cells from mouse bone marrow
- (2014) C. T. Mayer et al. BLOOD
- Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells
- (2014) Brian Ruffell et al. CANCER CELL
- Human XCR1+Dendritic Cells Derived In Vitro from CD34+Progenitors Closely Resemble Blood Dendritic Cells, Including Their Adjuvant Responsiveness, Contrary to Monocyte-Derived Dendritic Cells
- (2014) Sreekumar Balan et al. JOURNAL OF IMMUNOLOGY
- Epigenetic Control ofCcr7Expression in Distinct Lineages of Lung Dendritic Cells
- (2014) Timothy P. Moran et al. JOURNAL OF IMMUNOLOGY
- Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses
- (2013) G. Nizzoli et al. BLOOD
- Numerical defect of circulating dendritic cell subsets and defective dendritic cell generation from monocytes of patients with advanced melanoma
- (2013) Alessandra Failli et al. CANCER LETTERS
- Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients
- (2013) J. Tel et al. CANCER RESEARCH
- MicroRNA-155 Is Required for Effector CD8+ T Cell Responses to Virus Infection and Cancer
- (2013) Jan C. Dudda et al. IMMUNITY
- IL-12p70–producing patient DC vaccine elicits Tc1-polarized immunity
- (2013) Beatriz M. Carreno et al. JOURNAL OF CLINICAL INVESTIGATION
- Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ–resident dendritic cells
- (2013) Elodie Segura et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+dendritic cells at cross presentation
- (2013) Lillian Cohn et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Plasmacytoid Dendritic Cells Support Melanoma Progression by Promoting Th2 and Regulatory Immunity through OX40L and ICOSL
- (2013) C. Aspord et al. Cancer Immunology Research
- ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+T cells by plasmacytoid dendritic cells
- (2013) Julien Faget et al. OncoImmunology
- Plasmacytoid Dendritic Cells Promote Immunosuppression in Ovarian Cancer via ICOS Costimulation of Foxp3+ T-Regulatory Cells
- (2012) C. Conrad et al. CANCER RESEARCH
- The equivalents of human blood and spleen dendritic cell subtypes can be generated in vitro from human CD34+ stem cells in the presence of fms-like tyrosine kinase 3 ligand and thrombopoietin
- (2012) AI Proietto et al. Cellular & Molecular Immunology
- AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications
- (2012) Chang-Xuan You et al. OncoImmunology
- Sec22b Regulates Phagosomal Maturation and Antigen Crosspresentation by Dendritic Cells
- (2011) Ignacio Cebrian et al. CELL
- Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine
- (2011) Kanako L. Lewis et al. IMMUNITY
- Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection
- (2011) Linda M. Wakim et al. NATURE
- siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells
- (2010) W. Hobo et al. BLOOD
- Enhancement of DC vaccine potency by activating the PI3K/AKT pathway with a small interfering RNA targeting PTEN
- (2010) Jin Hee Kim et al. IMMUNOLOGY LETTERS
- Bacteria-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity
- (2010) F. Saccheri et al. Science Translational Medicine
- Limited Amounts of Dendritic Cells Migrate into the T-Cell Area of Lymph Nodes but Have High Immune Activating Potential in Melanoma Patients
- (2009) P. Verdijk et al. CLINICAL CANCER RESEARCH
- Generation of Human Dendritic Cells That Simultaneously Secrete IL-12 and Have Migratory Capacity by Adenoviral Gene Transfer of hCD40L in Combination With IFN-γ
- (2009) Ilka Knippertz et al. JOURNAL OF IMMUNOTHERAPY
- Natural Killer Cell Accumulation in Tumors Is Dependent on IFN- and CXCR3 Ligands
- (2008) M. Wendel et al. CANCER RESEARCH
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