Extreme makeover: Engineering the activity of a thermostable alcohol dehydrogenase (AdhD) fromPyrococcus furiosus

Substrate channelling as an approach to cascade reactions

(2016) Ian Wheeldon et al.   Nature Chemistry

Why reinvent the wheel? Building new proteins based on ready-made parts

(2016) Olga Khersonsky et al.   PROTEIN SCIENCE

Redesigning alcohol dehydrogenases/reductases for more efficient biosynthesis of enantiopure isomers

(2015) Rongzhen Zhang et al.   BIOTECHNOLOGY ADVANCES

Directed Evolution of Enzymes for Industrial Biocatalysis

(2015) Joanne L. Porter et al.   CHEMBIOCHEM

Cascade catalysis – strategies and challenges en route to preparative synthetic biology

(2015) Jan Muschiol et al.   CHEMICAL COMMUNICATIONS

The aldo-keto reductases (AKRs): Overview

(2015) Trevor M. Penning   CHEMICO-BIOLOGICAL INTERACTIONS

Ethanol production by engineered thermophiles

(2015) Daniel G Olson et al.   CURRENT OPINION IN BIOTECHNOLOGY

Recent advances in engineering proteins for biocatalysis

(2014) Ye Li et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein engineering for development of new hydrolytic biocatalysts

(2014) Mikael Widersten   CURRENT OPINION IN CHEMICAL BIOLOGY

Structural and biochemical characterisation of a NAD+-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications

(2013) Skander Elleuche et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Evolvability of Thermophilic Proteins from Archaea and Bacteria

(2013) Kazufumi Takano et al.   BIOCHEMISTRY

Complete Oxidation of Methanol in Biobattery Devices Using a Hydrogel Created from Three Modified Dehydrogenases

(2012) Yang Hee Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Systems metabolic engineering of microorganisms for natural and non-natural chemicals

(2012) Jeong Wook Lee et al.   Nature Chemical Biology

Modular exchange of substrate-binding loops alters both substrate and cofactor specificity in a member of the aldo-keto reductase superfamily

(2012) E. Campbell et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Enzymatic biofuel cells utilizing a biomimetic cofactor

(2011) Elliot Campbell et al.   CHEMICAL COMMUNICATIONS

Protein Engineering in the Development of Functional Hydrogels

(2010) Scott Banta et al.   Annual Review of Biomedical Engineering

Characterization of a Thermostable Short-Chain Alcohol Dehydrogenase from the Hyperthermophilic Archaeon Thermococcus sibiricus

(2010) T. N. Stekhanova et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Broadening the cofactor specificity of a thermostable alcohol dehydrogenase using rational protein design introduces novel kinetic transient behavior

(2010) Elliot Campbell et al.   BIOTECHNOLOGY AND BIOENGINEERING

Practical chiral alcohol manufacture using ketoreductases

(2010) Gjalt W Huisman et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Sulfolobus tokodaii ST0053 Produces a Novel Thermostable, NAD-Dependent Medium-Chain Alcohol Dehydrogenase

(2009) H. Yanai et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Chimeric Fusion Protein Engineered with Disparate Functionalities—Enzymatic Activity and Self–assembly

(2009) Ian R. Wheeldon et al.   JOURNAL OF MOLECULAR BIOLOGY

Establishing wild-type levels of catalytic activity on natural and artificial (  )8-barrel protein scaffolds

(2009) J. Claren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purification and Characterization of a Novel Recombinant Highly Enantioselective Short-Chain NAD(H)-Dependent Alcohol Dehydrogenase from Thermus thermophilus

(2008) A. Pennacchio et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic control analysis of an enzymatic biofuel cell

(2008) Doris J. Glykys et al.   BIOTECHNOLOGY AND BIOENGINEERING

The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

(2008) Oleg A. Barski et al.   DRUG METABOLISM REVIEWS

Laboratory evolution of Pyrococcus furiosus alcohol dehydrogenase to improve the production of (2S,5S)-hexanediol at moderate temperatures

(2008) Ronnie Machielsen et al.   EXTREMOPHILES

Bioelectrocatalytic hydrogels from electron-conducting metallopolypeptides coassembled with bifunctional enzymatic building blocks

(2008) I. R. Wheeldon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA