Newly identified bacteriolytic enzymes that target a wide range of clinical isolates ofClostridium difficile

Burden of Clostridium difficile Infection in the United States

(2015) Fernanda C. Lessa et al.   NEW ENGLAND JOURNAL OF MEDICINE

Growth inhibition of Mycobacterium smegmatis by mycobacteriophage-derived enzymes

(2014) Navdeep Grover et al.   ENZYME AND MICROBIAL TECHNOLOGY

A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice

(2014) Zhiyong Yang et al.   JOURNAL OF INFECTIOUS DISEASES

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Characterization of AmiBA2446, a Novel Bacteriolytic Enzyme Active against Bacillus Species

(2013) Krunal K. Mehta et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enzyme-Based Listericidal Nanocomposites

(2013) Kusum Solanki et al.   Scientific Reports

Characterization of a Novel Lytic Protein Encoded by the Bacillus cereus E33L GeneampDas a Bacillus anthracis Antimicrobial Protein

(2012) Feliza A. Bourguet et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Chimeric Toxin Vaccine Protects against Primary and Recurrent Clostridium difficile Infection

(2012) Haiying Wang et al.   INFECTION AND IMMUNITY

CDD: conserved domains and protein three-dimensional structure

(2012) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Lysostaphin-functionalized cellulose fibers with antistaphylococcal activity for wound healing applications

(2011) Jianjun Miao et al.   BIOMATERIALS

Mouse Relapse Model of Clostridium difficile Infection

(2011) Xingmin Sun et al.   INFECTION AND IMMUNITY

Structure-Based Modification of a Clostridium difficile-Targeting Endolysin Affects Activity and Host Range

(2011) M. J. Mayer et al.   JOURNAL OF BACTERIOLOGY

Clostridium difficileHas an Original Peptidoglycan Structure with a High Level ofN-Acetylglucosamine Deacetylation and Mainly 3-3 Cross-links

(2011) Johann Peltier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Dissemination of Clostridium difficile Toxins A and B Is Associated With Severe, Fatal Disease in Animal Models

(2011) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

Antistaphylococcal Nanocomposite Films Based on Enzyme−Nanotube Conjugates

(2010) Ravindra C. Pangule et al.   ACS Nano

Identifying Active Phage Lysins through Functional Viral Metagenomics

(2010) J. E. Schmitz et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

(2010) M. Merrigan et al.   JOURNAL OF BACTERIOLOGY

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Evolutionary dynamics of Clostridium difficile over short and long time scales

(2010) M. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

Structural analysis of theL-alanoyl-D-glutamate endopeptidase domain ofListeriabacteriophage endolysin Ply500 reveals a new member of the LAS peptidase family

(2008) Ingo P. Korndörfer et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Bacteriophage lysins as effective antibacterials

(2008) Vincent A Fischetti   CURRENT OPINION IN MICROBIOLOGY

Molecular Characterization of a Clostridium difficile Bacteriophage and Its Cloned Biologically Active Endolysin

(2008) M. J. Mayer et al.   JOURNAL OF BACTERIOLOGY

CDD: specific functional annotation with the Conserved Domain Database

(2008) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH