ToolBox: Live Imaging of intracellular organelle transport in induced pluripotent stem cell‐derived neurons

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

(2019) Joseph R. Klim et al.   NATURE NEUROSCIENCE

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity

(2019) Yong-Jie Zhang et al.   SCIENCE

A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons

(2019) Marieke Meijer et al.   Cell Reports

An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons

(2019) Hong Jun Rhee et al.   Cell Reports

Vesicular degradation pathways in neurons: at the crossroads of autophagy and endo-lysosomal degradation

(2019) C Alexander Boecker et al.   CURRENT OPINION IN NEUROBIOLOGY

Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons

(2018) Xiu-Tang Cheng et al.   JOURNAL OF CELL BIOLOGY

Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes

(2018) Chan Choo Yap et al.   JOURNAL OF CELL BIOLOGY

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

(2018) Tsung-Li Liu et al.   SCIENCE

Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons

(2018) Mara A. Olenick et al.   JOURNAL OF CELL BIOLOGY

Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes

(2017) Swathi Ayloo et al.   MOLECULAR BIOLOGY OF THE CELL

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

(2017) Brock Roberts et al.   MOLECULAR BIOLOGY OF THE CELL

Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes

(2017) Brett T Staahl et al.   NATURE BIOTECHNOLOGY

The impact of cytoskeletal organization on the local regulation of neuronal transport

(2017) Jeffrey J. Nirschl et al.   NATURE REVIEWS NEUROSCIENCE

Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

(2017) Roderick P. Tas et al.   NEURON

BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

(2017) Ginny G. Farías et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder

(2017) Aditi Deshpande et al.   Cell Reports

Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

(2017) Chao Wang et al.   Stem Cell Reports

In vivo and in vitro sex differences in the dendritic morphology of developing murine hippocampal and cortical neurons

(2017) Kimberly P. Keil et al.   Scientific Reports

Progressive Decrease of Mitochondrial Motility during Maturation of Cortical Axons In Vitro and In Vivo

(2016) Tommy L. Lewis et al.   CURRENT BIOLOGY

Compartment-Specific Regulation of Autophagy in Primary Neurons

(2016) Sandra Maday et al.   JOURNAL OF NEUROSCIENCE

Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome

(2016) G. E. Rooney et al.   JOURNAL OF NEUROSCIENCE

Compartmentalized Regulation of Parkin-Mediated Mitochondrial Quality Control in the Drosophila Nervous System In Vivo

(2016) H. Sung et al.   JOURNAL OF NEUROSCIENCE

Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment

(2016) Marijn Kuijpers et al.   NEURON

Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B

(2016) Amy E. Ghiretti et al.   NEURON

α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons

(2016) Jeffrey J. Nirschl et al.   Cell Reports

Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adultDrosophilaneurons

(2015) Alessio Vagnoni et al.   JOURNAL OF CELL SCIENCE

Neuronal morphometry directly from bitmap images

(2014) Tiago A Ferreira et al.   NATURE METHODS

Parkin Mutations Reduce the Complexity of Neuronal Processes in iPSC-Derived Human Neurons

(2014) Yong Ren et al.   STEM CELLS

An assay to image neuronal microtubule dynamics in mice

(2014) Tatjana Kleele et al.   Nature Communications

BDNF-Dependent Recycling Facilitates TrkB Translocation to Postsynaptic Density during LTP via a Rab11-Dependent Pathway

(2013) S.-H. Huang et al.   JOURNAL OF NEUROSCIENCE

BDNF Regulates Rab11-Mediated Recycling Endosome Dynamics to Induce Dendritic Branching

(2013) O. M. Lazo et al.   JOURNAL OF NEUROSCIENCE

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

(2013) Yingsha Zhang et al.   NEURON

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

In Vivo Imaging of Disease-Related Mitochondrial Dynamics in a Vertebrate Model System

(2012) G. Plucinska et al.   JOURNAL OF NEUROSCIENCE

Simple Neurite Tracer: open source software for reconstruction, visualization and analysis of neuronal processes

(2011) M. H. Longair et al.   BIOINFORMATICS

Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons

(2010) Qian Cai et al.   NEURON

Globally optimal stitching of tiled 3D microscopic image acquisitions

(2009) S. Preibisch et al.   BIOINFORMATICS