Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses

(2018) Jeong-Joong Yoon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Update: Influenza Activity in the United States During the 2017–18 Season and Composition of the 2018–19 Influenza Vaccine

(2018) Rebecca Garten et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

(2018) Frederick G. Hayden et al.   NEW ENGLAND JOURNAL OF MEDICINE

The mechanism of resistance to favipiravir in influenza

(2018) Daniel H. Goldhill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional fidelities of human mitochondrial POLRMT, yeast mitochondrial Rpo41, and phage T7 single-subunit RNA polymerases

(2017) Shemaila Sultana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-D- N 4 -Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome

(2017) Nadya Urakova et al.   JOURNAL OF VIROLOGY

A 3D Human Airway Model Enables Prediction of Respiratory Toxicity of Inhaled Drugs In Vitro

(2017) Kinga Balogh Sivars et al.   TOXICOLOGICAL SCIENCES

Drug resistance in influenza A virus: the epidemiology and management

(2017) Mazhar Hussain et al.   Infection and Drug Resistance

Identification and Characterization of Influenza Virus Entry Inhibitors through Dual Myxovirus High-Throughput Screening

(2016) Marco Weisshaar et al.   JOURNAL OF VIROLOGY

The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells

(2016) Nai-Huei Wu et al.   Scientific Reports

Characterization of the Localized Immune Response in the Respiratory Tract of Ferrets following Infection with Influenza A and B Viruses

(2015) Louise A. Carolan et al.   JOURNAL OF VIROLOGY

Ferret models of viral pathogenesis

(2015) T. Enkirch et al.   VIROLOGY

Characterization of Susceptibility Variants of Influenza Virus Grown in the Presence of T-705

(2014) Tohru Daikoku et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Severity of Clinical Disease and Pathology in Ferrets Experimentally Infected with Influenza Viruses Is Influenced by Inoculum Volume

(2014) I. N. Moore et al.   JOURNAL OF VIROLOGY

Low Dose Influenza Virus Challenge in the Ferret Leads to Increased Virus Shedding and Greater Sensitivity to Oseltamivir

(2014) Anthony C. Marriott et al.   PLoS One

An Overview of Respiratory Syncytial Virus

(2014) Jia Meng et al.   PLoS Pathogens

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro

(2013) T. Baranovich et al.   JOURNAL OF VIROLOGY

The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

(2013) Zhinan Jin et al.   PLoS One

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

The ability of animal studies to detect serious post marketing adverse events is limited

(2012) Peter J.K. van Meer et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Modification of the Ferret Model for Pneumonia From Seasonal Human Influenza A Virus Infection

(2012) J. M. A. van den Brand et al.   VETERINARY PATHOLOGY

Assessment of the efficacy of the neuraminidase inhibitor oseltamivir against 2009 pandemic H1N1 influenza virus in ferrets

(2011) Elena A. Govorkova et al.   ANTIVIRAL RESEARCH

Influenza-induced innate immunity: regulators of viral replication, respiratory tract pathology & adaptive immunity

(2011) Karen L Oslund et al.   Future Virology

The first influenza pandemic of the new millennium

(2011) Gabriele Neumann et al.   Influenza and Other Respiratory Viruses

The Human Airway Epithelial Basal Cell Transcriptome

(2011) Neil R. Hackett et al.   PLoS One

Higher Level of Replication Efficiency of 2009 (H1N1) Pandemic Influenza Virus than Those of Seasonal and Avian Strains: Kinetics from Epithelial Cell Culture and Computational Modeling

(2010) H. Mitchell et al.   JOURNAL OF VIROLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Animal Models for Influenza Virus Pathogenesis and Transmission

(2010) Nicole M. Bouvier et al.   Viruses-Basel

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Emergence and pandemic potential of swine-origin H1N1 influenza virus

(2009) Gabriele Neumann et al.   NATURE

Cloning, expression and characterization of ferret CXCL10

(2007) Ali Danesh et al.   MOLECULAR IMMUNOLOGY