Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina

Visualizing melanosomes, lipofuscin, and melanolipofuscin in human retinal pigment epithelium using serial block face scanning electron microscopy

(2018) Andreas Pollreisz et al.   EXPERIMENTAL EYE RESEARCH

Cuticular Drusen

(2018) Chandrakumar Balaratnasingam et al.   OPHTHALMOLOGY

THE PHYSIOLOGY OF THE RETINAL PIGMENT EPITHELIUM IN DANON DISEASE

(2016) Dorothy A. Thompson et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

HYPERSPECTRAL AUTOFLUORESCENCE IMAGING OF DRUSEN AND RETINAL PIGMENT EPITHELIUM IN DONOR EYES WITH AGE-RELATED MACULAR DEGENERATION

(2016) Yuehong Tong et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export

(2016) Jian Li et al.   eLife

Deletion of autophagy inducerRB1CC1results in degeneration of the retinal pigment epithelium

(2015) Jingyu Yao et al.   Autophagy

Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis

(2015) Mei Jiang et al.   JOURNAL OF CELL BIOLOGY

βA3/A1-crystallin: More than a lens protein

(2015) J. Samuel Zigler et al.   PROGRESS IN RETINAL AND EYE RESEARCH

LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease

(2015) Michelle Rothaug et al.   Acta Neuropathologica Communications

LAMP-2: A control step for phagosome and autophagosome maturation

(2014) Paul Saftig et al.   Autophagy

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

(2014) Sayak K Mitter et al.   Autophagy

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling

(2014) Mallika Valapala et al.   Autophagy

Autophagy in the eye: Implications for ocular cell health

(2014) Laura S. Frost et al.   EXPERIMENTAL EYE RESEARCH

The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium

(2014) Laura S. Frost et al.   MOLECULAR NEUROBIOLOGY

Chaperone-mediated autophagy: roles in neurodegeneration

(2014) Gang Wang et al.   Translational Neurodegeneration

Discovery of a novel type of autophagy targeting RNA

(2013) Yuuki Fujiwara et al.   Autophagy

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

Chaperone-mediated autophagy: roles in disease and aging

(2013) Ana Maria Cuervo et al.   CELL RESEARCH

Clinical Classification of Age-related Macular Degeneration

(2013) Frederick L. Ferris et al.   OPHTHALMOLOGY

Autofluorescence imaging of human RPE cell granules using structured illumination microscopy

(2012) Thomas Ach et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Cone-rod dystrophy can be a manifestation of Danon disease

(2012) Alberta A. H. J. Thiadens et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Mechanisms of Age-Related Macular Degeneration

(2012) Jayakrishna Ambati et al.   NEURON

Vascular Endothelial Growth Factor A in Intraocular Vascular Disease

(2012) Joan W. Miller et al.   OPHTHALMOLOGY

Retinal and Choroidal Thickness in Early Age-Related Macular Degeneration

(2011) Ashley Wood et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

The oil spill in ageing Bruch membrane

(2011) C. A. Curcio et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Age-Related Retinopathy in NRF2-Deficient Mice

(2011) Zhenyang Zhao et al.   PLoS One

Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice

(2011) Mei Chen et al.   PLoS One

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration

(2009) Ai Ling Wang et al.   PLoS One

Para-inflammation in the aging retina

(2009) Heping Xu et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Lysosomal myopathies: An excessive build-up in autophagosomes is too much to handle

(2008) May Christine Malicdan et al.   NEUROMUSCULAR DISORDERS

Age-Related Macular Degeneration

(2008) Rama D. Jager et al.   NEW ENGLAND JOURNAL OF MEDICINE

Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice

(2007) Heping Xu et al.   AGING CELL