Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth

A tRNA half modulates translation as stress response in Trypanosoma brucei

(2019) Roger Fricker et al.   Nature Communications

Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution

(2019) Vahid Khoddami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase

(2019) Zihao Yuan et al.   Cells

Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program

(2019) Maxime Janin et al.   ACTA NEUROPATHOLOGICA

Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex

(2019) Peipei Chen et al.   Molecular Brain

OPP Labeling Enables Total Protein Synthesis Quantification in CHO Production Cell Lines at the Single-Cell Level

(2018) Fabian Nagelreiter et al.   Biotechnology Journal

Structural and evolutionary insights into ribosomal RNA methylation

(2018) Petr V Sergiev et al.   Nature Chemical Biology

OPP Labeling Enables Total Protein Synthesis Quantification in CHO Production Cell Lines at the Single-Cell Level

(2018) Fabian Nagelreiter et al.   Biotechnology Journal

The Discovery of Ribosome Heterogeneity and Its Implications for Gene Regulation and Organismal Life

(2018) Naomi R. Genuth et al.   MOLECULAR CELL

Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts

(2018) Barbara Herdy et al.   NUCLEIC ACIDS RESEARCH

Cognitive deficits in mice lacking Nsun5, a cytosine-5 RNA methyltransferase, with impairment of oligodendrocyte precursor cells

(2018) Tingting Zhang et al.   GLIA

The dynamic RNA modification 5‐methylcytosine and its emerging role as an epitranscriptomic mark

(2018) Lukas Trixl et al.   Wiley Interdisciplinary Reviews-RNA

Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

(2017) Carine Legrand et al.   GENOME RESEARCH

Visualization of chemical modifications in the human 80S ribosome structure

(2017) S. Kundhavai Natchiar et al.   NATURE

Transcription by RNA polymerase III: insights into mechanism and regulation

(2016) Tomasz W. Turowski et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The importance of being (slightly) modified: The role of rRNA editing on gene expression control and its connections with cancer

(2016) Marianna Penzo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

High-throughput discovery of novel developmental phenotypes

(2016) Mary E. Dickinson et al.   NATURE

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

Human ribosomes from cells with reduced dyskerin levels are intrinsically altered in translation

(2015) Marianna Penzo et al.   FASEB JOURNAL

The expanding role of mTOR in cancer cell growth and proliferation

(2015) Marie Cargnello et al.   MUTAGENESIS

‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification

(2015) Sunny Sharma et al.   TRENDS IN BIOCHEMICAL SCIENCES

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

(2015) Markus Schosserer et al.   Nature Communications

A cluster of methylations in the domain IV of 25S rRNA is required for ribosome stability

(2014) Andriana Gigova et al.   RNA

Cotranscriptional events in eukaryotic ribosome synthesis

(2014) Tomasz W. Turowski et al.   Wiley Interdisciplinary Reviews-RNA

The Regulation of Cell Size

(2013) Alison C. Lloyd   CELL

Identification of direct targets and modified bases of RNA cytosine methyltransferases

(2013) Vahid Khoddami et al.   NATURE BIOTECHNOLOGY

Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively

(2013) Sunny Sharma et al.   NUCLEIC ACIDS RESEARCH

Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage

(2013) J. Azpurua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

(2013) Shobbir Hussain et al.   Cell Reports

Conservation between the RNA Polymerase I, II, and III Transcription Initiation Machineries

(2012) Alessandro Vannini et al.   MOLECULAR CELL

Specialized ribosomes: a new frontier in gene regulation and organismal biology

(2012) Shifeng Xue et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension

(2011) P. Di Tommaso et al.   NUCLEIC ACIDS RESEARCH

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size

(2010) Christine Müller et al.   EMBO JOURNAL

Yeast Pre-rRNA Processing and Modification Occur Cotranscriptionally

(2010) Martin Koš et al.   MOLECULAR CELL

Williams–Beuren Syndrome

(2010) Barbara R. Pober   NEW ENGLAND JOURNAL OF MEDICINE

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice

(2009) Hong Hua Li et al.   EMBO Molecular Medicine

The genomic basis of the Williams – Beuren syndrome

(2008) C. Schubert   CELLULAR AND MOLECULAR LIFE SCIENCES

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

(2008) Ina Poser et al.   NATURE METHODS