Structural and evolutionary insights into ribosomal RNA methylation

Biogenesis and iron-dependency of ribosomal RNA hydroxylation

(2017) Satoshi Kimura et al.   NUCLEIC ACIDS RESEARCH

The structure of the yeast mitochondrial ribosome

(2017) Nirupa Desai et al.   SCIENCE

Mapping of Complete Set of Ribose and Base Modifications of Yeast rRNA by RP-HPLC and Mung Bean Nuclease Assay

(2017) Jun Yang et al.   PLoS One

Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome

(2016) Markus Kornprobst et al.   CELL

NML-mediated rRNA base methylation links ribosomal subunit formation to cell proliferation in a p53-dependent manner

(2016) Tsuyoshi Waku et al.   JOURNAL OF CELL SCIENCE

Blast from the Past: Reassessing Forgotten Translation Inhibitors, Antibiotic Selectivity, and Resistance Mechanisms to Aid Drug Development

(2016) Stefan Arenz et al.   MOLECULAR CELL

Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans

(2016) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates

(2016) Dan Bar-Yaacov et al.   PLOS BIOLOGY

The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

(2015) Christiane Zorbas et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A

(2015) Yury S. Polikanov et al.   MOLECULAR CELL

Structure of the human 80S ribosome

(2015) Heena Khatter et al.   NATURE

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-resolution structure of the Escherichia coli ribosome

(2015) Jonas Noeske et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The structure of the human mitochondrial ribosome

(2015) A. Amunts et al.   SCIENCE

‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification

(2015) Sunny Sharma et al.   TRENDS IN BIOCHEMICAL SCIENCES

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

(2015) Markus Schosserer et al.   Nature Communications

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-resolution structure of the Escherichia coli ribosome

(2015) Jonas Noeske et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120

(2015) Gabrielle Bourgeois et al.   PLoS One

Assignment of 2′-O-Methyltransferases to Modification Sites on the Mammalian Mitochondrial Large Subunit 16 S Ribosomal RNA (rRNA)

(2014) Ken-Wing Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative Analysis of rRNA Modifications Using Stable Isotope Labeling and Mass Spectrometry

(2014) Anna M. Popova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

The flavoprotein Mcap0476 (RlmFO) catalyzes m5U1939 modification inMycoplasma capricolum23S rRNA

(2014) Carole Lartigue et al.   NUCLEIC ACIDS RESEARCH

The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21

(2014) Katherine E. Sloan et al.   NUCLEIC ACIDS RESEARCH

Structural and functional studies of Bud23–Trm112 reveal 18S rRNAN7-G1575 methylation occurs on late 40S precursor ribosomes

(2014) Juliette Létoquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WBSCR22/Merm1 is required for late nuclear pre-ribosomal RNA processing and mediates N7-methylation of G1639 in human 18S rRNA

(2014) Sara Haag et al.   RNA

Hepatic rRNA Transcription Regulates High-Fat-Diet-Induced Obesity

(2014) Shohei Oie et al.   Cell Reports

NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly

(2014) Metodi Dimitrov Metodiev et al.   PLoS Genetics

Structures of the human and Drosophila 80S ribosome

(2013) Andreas M. Anger et al.   NATURE

Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae

(2013) Sunny Sharma et al.   NUCLEIC ACIDS RESEARCH

Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively

(2013) Sunny Sharma et al.   NUCLEIC ACIDS RESEARCH

Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae

(2013) S. Sharma et al.   NUCLEIC ACIDS RESEARCH

Distinctive contributions of the ribosomal P-site elements m2G966, m5C967 and the C-terminal tail of the S9 protein in the fidelity of initiation of translation in Escherichia coli

(2013) S. Arora et al.   NUCLEIC ACIDS RESEARCH

Modified nucleotides m2G966/m5C967 of Escherichia coli 16S rRNA are required for attenuation of tryptophan operon

(2013) Irina V. Prokhorova et al.   Scientific Reports

Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity

(2012) Satoshi Kimura et al.   NUCLEIC ACIDS RESEARCH

Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA

(2012) Christian Peifer et al.   NUCLEIC ACIDS RESEARCH

Impact of methylations of m2G966/m5C967 in 16S rRNA on bacterial fitness and translation initiation

(2012) Dmitry E. Burakovsky et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

The last rRNA methyltransferase of E. coli revealed: The yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA

(2012) A. Y. Golovina et al.   RNA

Trmt61B is a methyltransferase responsible for 1-methyladenosine at position 58 of human mitochondrial tRNAs

(2012) T. Chujo et al.   RNA

A Common Variant in TFB1M Is Associated with Reduced Insulin Secretion and Increased Future Risk of Type 2 Diabetes

(2011) Thomas Koeck et al.   Cell Metabolism

YhiQ Is RsmJ, the Methyltransferase Responsible for Methylation of G1516 in 16S rRNA of E. coli

(2011) Georgeta N. Basturea et al.   JOURNAL OF MOLECULAR BIOLOGY

A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA

(2011) Benoit Desmolaize et al.   NUCLEIC ACIDS RESEARCH

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

The ribosome assembly factor Nep1 responsible for Bowen–Conradi syndrome is a pseudouridine-N1-specific methyltransferase

(2010) Jan Philip Wurm et al.   NUCLEIC ACIDS RESEARCH

The Bowen–Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA

(2010) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

Subribosomal particle analysis reveals the stages of bacterial ribosome assembly at which rRNA nucleotides are modified

(2010) T. Siibak et al.   RNA

Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function

(2010) H. Demirci et al.   RNA

Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome

(2009) Joy Armistead et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness

(2009) Justin Cotney et al.   HUMAN MOLECULAR GENETICS

YgdE is the 2′-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA

(2009) Elzbieta Purta et al.   MOLECULAR MICROBIOLOGY

Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA

(2009) Satoshi Kimura et al.   NUCLEIC ACIDS RESEARCH

Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracy

(2009) Agnès Baudin-Baillieu et al.   NUCLEIC ACIDS RESEARCH

Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria

(2009) A. M. B. Giessing et al.   RNA

YccW is the m5C Methyltransferase Specific for 23S rRNA Nucleotide 1962

(2008) Elzbieta Purta et al.   JOURNAL OF MOLECULAR BIOLOGY

Bud23 Methylates G1575 of 18S rRNA and Is Required for Efficient Nuclear Export of Pre-40S Subunits

(2008) J. White et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA

(2008) Keith Connolly et al.   MOLECULAR MICROBIOLOGY

YbeA is the m3  methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA

(2008) E. Purta et al.   RNA

The ybiN Gene of Escherichia coli Encodes Adenine-N6 Methyltransferase Specific for Modification of A1618 of 23 S Ribosomal RNA, a Methylated Residue Located Close to the Ribosomal Exit Tunnel

(2007) Petr V. Sergiev et al.   JOURNAL OF MOLECULAR BIOLOGY