Engineering DNA recognition and allosteric response properties of TetR family proteins by using a module-swapping strategy

Rewiring bacterial two-component systems by modular DNA-binding domain swapping

(2019) Sebastian R. Schmidl et al.   Nature Chemical Biology

Engineering repressors with coevolutionary cues facilitates toggle switches with a master reset

(2019) Rey P Dimas et al.   NUCLEIC ACIDS RESEARCH

Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors

(2018) Adam J. Meyer et al.   Nature Chemical Biology

Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors

(2017) Toni A. Baeumler et al.   Cell Reports

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

(2016) Leonardo Morsut et al.   CELL

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors

(2016) Kole T. Roybal et al.   CELL

Modular organisation of inducer recognition and allostery in the tetracycline repressor

(2016) Sebastiaan Werten et al.   FEBS Journal

The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism inMycobacterium tuberculosis

(2016) Ngoc Anh Thu Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Creating Single-Copy Genetic Circuits

(2016) Jeong Wook Lee et al.   MOLECULAR CELL

Rewiring human cellular input–output using modular extracellular sensors

(2016) Kelly A Schwarz et al.   Nature Chemical Biology

'Deadman' and 'Passcode' microbial kill switches for bacterial containment

(2015) Clement T Y Chan et al.   Nature Chemical Biology

Synthetic biosensors for precise gene control and real-time monitoring of metabolites

(2015) Jameson K. Rogers et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Principles of genetic circuit design

(2014) Jennifer A N Brophy et al.   NATURE METHODS

Design and characterization of a dual-mode promoter with activation and repression capability for tuning gene expression in yeast

(2014) Mostafizur Mazumder et al.   NUCLEIC ACIDS RESEARCH

Advances in genetic circuit design: novel biochemistries, deep part mining, and precision gene expression

(2013) Alec AK Nielsen et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A wise consistency: engineering biology for conformity, reliability, predictability

(2013) Adam Paul Arkin   CURRENT OPINION IN CHEMICAL BIOLOGY

The TetR Family of Regulators

(2013) L. Cuthbertson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Engineering robust control of two-component system phosphotransfer using modular scaffolds

(2012) W. R. Whitaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chimeric Antigen Receptor Therapy for B-cell Malignancies

(2012) David L Porter et al.   Journal of Cancer

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tracking, tuning, and terminating microbial physiology using synthetic riboregulators

(2010) J. M. Callura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Function of the Macrolide Biosensor Protein, MphR(A), with and without Erythromycin

(2009) Jianting Zheng et al.   JOURNAL OF MOLECULAR BIOLOGY

Next-generation synthetic gene networks

(2009) Timothy K Lu et al.   NATURE BIOTECHNOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

The second wave of synthetic biology: from modules to systems

(2009) Priscilla E. M. Purnick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

QacR−Cation Recognition Is Mediated by a Redundancy of Residues Capable of Charge Neutralization†

(2008) Kate M. Peters et al.   BIOCHEMISTRY

Tet Repressor Induction by Tetracycline: A Molecular Dynamics, Continuum Electrostatics, and Crystallographic Study

(2008) Alexey Aleksandrov et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis

(2008) Wen-Yih Jeng et al.   NUCLEIC ACIDS RESEARCH