The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function
出版年份 2019 全文链接
标题
The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function
作者
关键词
-
出版物
NATURE
Volume 574, Issue 7777, Pages 249-253
出版商
Springer Science and Business Media LLC
发表日期
2019-10-03
DOI
10.1038/s41586-019-1615-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation
- (2018) Corinne Urwyler-Rösselet et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity
- (2018) Christine S. Huang et al. STRUCTURE
- PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides
- (2017) Susanne Grond et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
- (2017) M Ryan Corces et al. NATURE METHODS
- Complex heatmaps reveal patterns and correlations in multidimensional genomic data
- (2016) Zuguang Gu et al. BIOINFORMATICS
- Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palate
- (2015) Huan Liu et al. HUMAN MOLECULAR GENETICS
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- A novel RIPK4–IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes
- (2014) P De Groote et al. CELL DEATH AND DIFFERENTIATION
- Receptor-interacting Protein Kinase 4 and Interferon Regulatory Factor 6 Function as a Signaling Axis to Regulate Keratinocyte Differentiation
- (2014) Mei Qi Kwa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NovelIRF6mutations in families with Van Der Woude syndrome and popliteal pterygium syndrome from sub-Saharan Africa
- (2014) Azeez Butali et al. Molecular Genetics & Genomic Medicine
- Dominant Mutations in GRHL3 Cause Van der Woude Syndrome and Disrupt Oral Periderm Development
- (2013) Myriam Peyrard-Janvid et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A double take on bivalent promoters
- (2013) P. Voigt et al. GENES & DEVELOPMENT
- Impaired Epidermal Ceramide Synthesis Causes Autosomal Recessive Congenital Ichthyosis and Reveals the Importance of Ceramide Acyl Chain Length
- (2013) Katja-Martina Eckl et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase
- (2013) Edward Ryder et al. TRANSGENIC RESEARCH
- Interferon Regulatory Factor 6 Promotes Differentiation of the Periderm by Activating Expression of Grainyhead-Like 3
- (2012) Gabriel de la Garza et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Exome Sequence Identifies RIPK4 as the Bartsocas- Papas Syndrome Locus
- (2011) Karen Mitchell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mutations in RIPK4 Cause the Autosomal-Recessive Form of Popliteal Pterygium Syndrome
- (2011) Ersan Kalay et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Loss of ceramide synthase 3 causes lethal skin barrier disruption
- (2011) Richard Jennemann et al. HUMAN MOLECULAR GENETICS
- Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas
- (2011) E. Botti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two missense mutations of the IRF6 gene in two Japanese families with popliteal pterygium syndrome
- (2010) Noriko Matsuzawa et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- RIP4 Regulates Epidermal Differentiation and Cutaneous Inflammation
- (2009) Ryan B. Rountree et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- MEME SUITE: tools for motif discovery and searching
- (2009) T. L. Bailey et al. NUCLEIC ACIDS RESEARCH
- Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6
- (2008) Hayley J. Little et al. HUMAN MOLECULAR GENETICS
- Skin stem cells: rising to the surface
- (2008) Elaine Fuchs JOURNAL OF CELL BIOLOGY
- Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5
- (2008) Weijun Chen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started