Maresin 1 Regulates Hepatic FGF21 in Diet‐Induced Obese Mice and in Cultured Hepatocytes

A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis

(2019) Yong-Hyun Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Maresin 1 attenuates NAFLD by suppression of endoplasmic reticulum stress via AMPK–SERCA2b pathway

(2018) Tae Woo Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maresin 1 improves insulin sensitivity and attenuates adipose tissue inflammation in ob/ob and diet-induced obese mice

(2017) Leyre Martínez-Fernández et al.   FASEB JOURNAL

The specialized proresolving lipid mediator maresin 1 protects hepatocytes from lipotoxic and hypoxia-induced endoplasmic reticulum stress

(2017) Bibiana Rius et al.   FASEB JOURNAL

Isocaloric Diets High in Animal or Plant Protein Reduce Liver Fat and Inflammation in Individuals With Type 2 Diabetes

(2017) Mariya Markova et al.   GASTROENTEROLOGY

Maresin 1 mitigates liver steatosis in ob/ob and diet-induced obese mice

(2017) L M Laiglesia et al.   INTERNATIONAL JOURNAL OF OBESITY

Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity

(2016) Ricardo J. Samms et al.   ENDOCRINOLOGY

Pro-resolving mediators produced from EPA and DHA: Overview of the pathways involved and their mechanisms in metabolic syndrome and related liver diseases

(2016) Cristina López-Vicario et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Fibroblast Growth Factor 21 As an Emerging Therapeutic Target for Type 2 Diabetes Mellitus

(2016) Wing Yan So et al.   MEDICINAL RESEARCH REVIEWS

AMPK Phosphorylates Desnutrin/ATGL and Hormone-Sensitive Lipase To Regulate Lipolysis and Fatty Acid Oxidation within Adipose Tissue

(2016) Sun-Joong Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes

(2016) Tania Quesada-López et al.   Nature Communications

Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet

(2015) Naoki Tanaka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

(2014) K. R. Markan et al.   DIABETES

A GAPDH-Mediated Trans-Nitrosylation Pathway Is Required for Feedback Inhibition of Bile Salt Synthesis in Rat Liver

(2014) Carlos M. Rodríguez-Ortigosa et al.   GASTROENTEROLOGY

Fibroblast Growth Factor-21 and the Beneficial Effects of Long-Chain n-3 Polyunsaturated Fatty Acids

(2014) Joan Villarroya et al.   LIPIDS

Glucagon Stimulates Hepatic FGF21 Secretion through a PKA- and EPAC-Dependent Posttranscriptional Mechanism

(2014) Holly A. Cyphert et al.   PLoS One

Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation

(2013) A. Neuhofer et al.   DIABETES

Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice

(2013) João Paulo G. Camporez et al.   ENDOCRINOLOGY

FGF21 suppresses hepatic glucose production through the activation of atypical protein kinase Cι/λ

(2013) Ling-Jie Kong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

(2012) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

(2011) Fredirick L. Mashili et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21)in Vivo

(2011) ffolliott M. Fisher et al.   ENDOCRINOLOGY

Lack of Overt FGF21 Resistance in Two Mouse Models of Obesity and Insulin Resistance

(2011) Clarence Hale et al.   ENDOCRINOLOGY

The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes

(2011) Y. Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

(2010) f. M. Fisher et al.   DIABETES

Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

(2010) Jody Dushay et al.   GASTROENTEROLOGY

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

(2010) Klementina Fon Tacer et al.   MOLECULAR ENDOCRINOLOGY

Relevant use of Klotho in FGF19 subfamily signaling system in vivo

(2010) K.-i. Tomiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man

(2008) Cecilia Gälman et al.   Cell Metabolism

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY

FGF21 is an Akt-regulated myokine

(2008) Yasuhiro Izumiya et al.   FEBS LETTERS

βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3c

(2008) Masashi Suzuki et al.   MOLECULAR ENDOCRINOLOGY