期刊
MATERIALS LETTERS
卷 253, 期 -, 页码 95-98出版社
ELSEVIER
DOI: 10.1016/j.matlet.2019.06.042
关键词
Biomaterials; Functional; TiO2; Hydrogen; PIII; Osteogenesis
资金
- National Natural Science Foundation of China [51831011, 31670980]
- National Natural Science Foundation for Distinguished Young Scholars of China [51525207]
- Science and Technology Commission of Shanghai Municipality [18YF1426900, 18410760600]
- High-end Entrepreneurial and Innovative Teams of Ningbo High-level Talents Project [2018A-09-C]
Titanium implants fabricated by micro-arc oxidation (MAO) are widely used in orthopedic therapies. However, TiO2 is a bio-inert material and lacks antibacterial properties. Therefore, it is crucial to enhance the biological activity and antibacterial properties of MAO implants. In this work, TiO2 coatings were fabricated by MAO and further hydrogen plasma immersion ion implantation (H-PIII). The formation of Ti-OH bonds promoted cell proliferation and osteogenic differentiation. The presence of Ti3+ and oxygen vacancies narrowed the forbidden band of TiO2 and showed bacteriostatic effect to E. coli. and S. aureus. (C) 2019 Elsevier B.V. All rights reserved.
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