Neutrophil extracellular traps are a source of extracellular HMGB1 in lupus nephritis: associations with clinical and histopathological features

Neutrophil Extracellular Traps protein composition is specific for patients with Lupus nephritis and includes methyl-oxidized αenolase (methionine sulfoxide 93)

(2019) Maurizio Bruschi et al.   Scientific Reports

The role of neutrophil extracellular traps in rheumatic diseases

(2018) Falko Apel et al.   Nature Reviews Rheumatology

Redefining lupus nephritis: clinical implications of pathophysiologic subtypes

(2017) Feng Yu et al.   Nature Reviews Nephrology

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients

(2016) Romain Banchereau et al.   CELL

TLR2 Plays a Critical Role in HMGB1-Induced Glomeruli Cell Proliferation Through the FoxO1 Signaling Pathway in Lupus Nephritis

(2016) Xiao-juan Feng et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Urinary high-mobility group box-1 associates specifically with lupus nephritis class V

(2016) N R Jog et al.   LUPUS

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis

(2015) Xiaoyun Li et al.   MOLECULAR IMMUNOLOGY

IL-1β enhances vascular smooth muscle cell proliferation and migration via P2Y2 receptor-mediated RAGE expression and HMGB1 release

(2015) So Young Eun et al.   VASCULAR PHARMACOLOGY

Antibodies against High Mobility Group Box protein-1 (HMGB1) versus other anti-nuclear antibody fine-specificities and disease activity in systemic lupus erythematosus

(2015) Lina Wirestam et al.   ARTHRITIS RESEARCH & THERAPY

Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2

(2014) Carmelo Carmona-Rivera et al.   ANNALS OF THE RHEUMATIC DISEASES

Elevated Plasma cfDNA May be Associated with Active Lupus Nephritis and Partially Attributed to Abnormal Regulation of Neutrophil Extracellular Traps (NETs) in Patients with Systemic Lupus Erythematosus

(2014) Sigong Zhang et al.   INTERNAL MEDICINE

Human neutrophil peptide 1-3, a component of the neutrophil extracellular trap, as a potential biomarker of lupus nephritis

(2014) Fa-Juan Cheng et al.   International Journal of Rheumatic Diseases

Redox Modulation of HMGB1-Related Signaling

(2013) Christina Janko et al.   ANTIOXIDANTS & REDOX SIGNALING

Autoantibody Induction by DNA-Containing Immune Complexes Requires HMGB1 with the TLR2/MicroRNA-155 Pathway

(2013) Z. Wen et al.   JOURNAL OF IMMUNOLOGY

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

(2013) Huan Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

HMGB1 mediates IFN-γ-induced cell proliferation in MMC cells through regulation of cyclin D1/CDK4/p16 pathway

(2012) Xiaojuan Feng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

(2012) Emilie Venereau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

Urine levels of HMGB1 in Systemic Lupus Erythematosus patients with and without renal manifestations

(2012) Deena A Abdulahad et al.   ARTHRITIS RESEARCH & THERAPY

Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis

(2012) Agneta Zickert et al.   ARTHRITIS RESEARCH & THERAPY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Neutrophils in the pathogenesis and manifestations of SLE

(2011) Mariana J. Kaplan   Nature Reviews Rheumatology

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Measures of adult systemic lupus erythematosus: Updated Version of British Isles Lupus Assessment Group (BILAG 2004), European Consensus Lupus Activity Measurements (ECLAM), Systemic Lupus Activity Measure, Revised (SLAM-R), Systemic Lupus Activity Questi

(2011) Juanita Romero-Diaz et al.   ARTHRITIS CARE & RESEARCH

High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus

(2011) Deena A Abdulahad et al.   ARTHRITIS RESEARCH & THERAPY

Therapeutic opportunities in systemic lupus erythematosus: state of the art and prospects for the new decade

(2010) G. K. Bertsias et al.   ANNALS OF THE RHEUMATIC DISEASES

Expression of High Mobility Group Box Chromosomal Protein 1 and Its Modulating Effects on Downstream Cytokines in Systemic Lupus Erythematosus

(2010) J. LI et al.   JOURNAL OF RHEUMATOLOGY

Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-alpha and TNF-alpha in systemic lupus erythematosus

(2010) Chun-yan Ma et al.   RHEUMATOLOGY INTERNATIONAL

Type I Interferons Produced by Resident Renal Cells May Promote End-Organ Disease in Autoantibody-Mediated Glomerulonephritis

(2009) A.-M. Fairhurst et al.   JOURNAL OF IMMUNOLOGY

High Mobility Group Box 1: a potential therapeutic target for systemic lupus erythematosus

(2009) Hai-Feng Pan et al.   MOLECULAR BIOLOGY REPORTS

Pathogenic anti-DNA antibodies modulate gene expression in mesangial cells: Involvement of HMGB1 in anti-DNA antibody-induced renal injury

(2008) Xiaoping Qing et al.   IMMUNOLOGY LETTERS