Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment

Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid–Mediated Troglitazone Hepatotoxicity

(2014) K Yang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Drug disposition alterations in liver disease: extrahepatic effects in cholestasis and nonalcoholic steatohepatitis

(2014) Mark J Canet et al.   Expert Opinion on Drug Metabolism & Toxicology

In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

(2013) K L R Brouwer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11)

(2013) Jenny M. Pedersen et al.   TOXICOLOGICAL SCIENCES

Bile acid transporters and regulatory nuclear receptors in the liver and beyond

(2012) Emina Halilbasic et al.   JOURNAL OF HEPATOLOGY

Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

(2012) Juan C. García-Cañaveras et al.   JOURNAL OF LIPID RESEARCH

Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-signali

(2011) Jin Chai et al.   HEPATOLOGY

Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug–drug interaction to support regulatory submissions

(2011) Robert Elsby et al.   XENOBIOTICA

Contribution of High Basolateral Bile Salt Efflux to the Lack of Hepatotoxicity in Rat in Response to Drugs Inducing Cholestasis in Human

(2010) Katalin Jemnitz et al.   TOXICOLOGICAL SCIENCES

Effect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and Inhibitors

(2009) E. Kis et al.   DRUG METABOLISM AND DISPOSITION

Compensatory role of P-glycoproteins in knockout mice lacking the bile salt export pump

(2009) Renxue Wang et al.   HEPATOLOGY

Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability

(2009) Richard H. Ho et al.   Pharmacogenetics and Genomics

Severe Bile Salt Export Pump Deficiency: 82 Different ABCB11 Mutations in 109 Families

(2008) Sandra S. Strautnieks et al.   GASTROENTEROLOGY

Degradation of the bile salt export pump at endoplasmic reticulum in progressive familial intrahepatic cholestasis type II

(2008) Lin Wang et al.   HEPATOLOGY

Involvement of Multiple Efflux Transporters in Hepatic Disposition of Fexofenadine

(2008) S. Matsushima et al.   MOLECULAR PHARMACOLOGY