Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of anticoagulants

Human soluble thrombomodulin-induced blockade of peripheral HMGB1-dependent allodynia in mice requires both the lectin-like and EGF-like domains

(2018) Yusuke Hayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Extracellular HMGB1 as a therapeutic target in inflammatory diseases

(2018) Ulf Andersson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Paclitaxel-induced HMGB1 release from macrophages and its implication for peripheral neuropathy in mice: Evidence for a neuroimmune crosstalk

(2018) Fumiko Sekiguchi et al.   NEUROPHARMACOLOGY

Pharmacotherapy options for managing chemotherapy-induced peripheral neurotoxicity

(2017) Guido Cavaletti et al.   EXPERT OPINION ON PHARMACOTHERAPY

Macrophage-derived HMGB1 as a Pain Mediator in the Early Stage of Acute Pancreatitis in Mice: Targeting RAGE and CXCL12/CXCR4 Axis

(2017) Yuhei Irie et al.   Journal of Neuroimmune Pharmacology

Role of Thrombin in Soluble Thrombomodulin-Induced Suppression of Peripheral HMGB1-Mediated Allodynia in Mice

(2017) Ryuichi Tsujita et al.   Journal of Neuroimmune Pharmacology

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

(2017) Satoshi Imai et al.   Scientific Reports

Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin

(2017) Takahito Miyake et al.   Frontiers in Physiology

Characterisation of Immune and Neuroinflammatory Changes Associated with Chemotherapy-Induced Peripheral Neuropathy

(2017) Preet G. S. Makker et al.   PLoS One

Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy

(2016) Hongmei Zhang et al.   JOURNAL OF PAIN

Peripheral HMGB1-induced hyperalgesia in mice: Redox state-dependent distinct roles of RAGE and TLR4

(2016) Daichi Yamasoba et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Interleukin-10 does not modulate clopidogrel platelet response in mice

(2016) Q. Yin et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Therapeutic potential of RQ-00311651, a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain

(2016) Fumiko Sekiguchi et al.   PAIN

Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats

(2016) Takeshi Nishida et al.   TOXICOLOGY

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

(2016) Takahito Miyake et al.   Nature Communications

HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia

(2016) Nabanita Das et al.   Cell Reports

Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss

(2016) Tsung-Lin Cheng et al.   Scientific Reports

Thrombomodulin as an intravascular safeguard against inflammatory and thrombotic diseases

(2015) Takashi Ito et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

CX3CL1-mediated macrophage activation contributed to paclitaxel-induced DRG neuronal apoptosis and painful peripheral neuropathy

(2014) Zhen-Zhen Huang et al.   BRAIN BEHAVIOR AND IMMUNITY

Gabapentin Prevents Oxaliplatin-Induced Mechanical Hyperalgesia in Mice

(2014) Masahiro Ohsawa et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis

(2014) Nilesh M. Agalave et al.   PAIN

Recombinant Lectin-Like Domain of Thrombomodulin Suppresses Vascular Inflammation by Reducing Leukocyte Recruitment via Interacting With Lewis Y on Endothelial Cells

(2013) Wei-Ling Lin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Recombinant human soluble thrombomodulin prevents peripheral HMGB1-dependent hyperalgesia in rats

(2013) Junichi Tanaka et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroprotective effects of argatroban and C5a receptor antagonist (PMX53) following intracerebral haemorrhage

(2013) G. Li et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents

(2013) Benoit Michot et al.   NEUROPHARMACOLOGY

Decreased thrombomodulin mRNA expression on peripheral monocytes in disseminated intravascular coagulation patients relates to poor outcomes: The ex vivo effects of lipopolysaccharide and thrombin on monocyte thrombomodulin and CD14 mRNA

(2013) Sung Kuk Hong et al.   THROMBOSIS RESEARCH

Secondary Intracerebral Hemorrhage Due to Early Initiation of Oral Anticoagulation After Ischemic Stroke

(2012) Michael Gliem et al.   STROKE

High-mobility group box family of proteins: ligand and sensor for innate immunity

(2012) Hideyuki Yanai et al.   TRENDS IN IMMUNOLOGY

Anti-platelet effects of yuzu extract and its component

(2011) Hye Yon Yu et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibition of T-type calcium channels and hydrogen sulfide-forming enzyme reverses paclitaxel-evoked neuropathic hyperalgesia in rats

(2011) K. Okubo et al.   NEUROSCIENCE

Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel

(2011) W.H. Xiao et al.   NEUROSCIENCE

Proteolytic Cleavage of High Mobility Group Box 1 Protein by Thrombin-Thrombomodulin Complexes

(2008) Takashi Ito et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY