GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway
出版年份 2019 全文链接
标题
GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 38, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-10-31
DOI
10.1186/s13046-019-1459-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- GSTZ 1‐1 Deficiency Activates NRF 2/ IGF 1R Axis in HCC via Accumulation of Oncometabolite Succinylacetone
- (2019) Fan Yang et al. EMBO JOURNAL
- NRF2 and the Hallmarks of Cancer
- (2018) Montserrat Rojo de la Vega et al. CANCER CELL
- Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases
- (2018) Nerino Allocati et al. Oncogenesis
- Antioxidant response elements: Discovery, classes, regulation and potential applications
- (2018) Azhwar Raghunath et al. Redox Biology
- 4-Hydroxynonenal metabolites and adducts in pre-carcinogenic conditions and cancer
- (2017) Françoise Guéraud FREE RADICAL BIOLOGY AND MEDICINE
- Transcriptional Regulation by Nrf2
- (2017) Claudia Tonelli et al. ANTIOXIDANTS & REDOX SIGNALING
- GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate
- (2016) Stephan C. Jahn et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Hypersuccinylacetonaemia and normal liver function in maleylacetoacetate isomerase deficiency
- (2016) Hao Yang et al. JOURNAL OF MEDICAL GENETICS
- The Dual Roles of NRF2 in Cancer
- (2016) Silvia Menegon et al. TRENDS IN MOLECULAR MEDICINE
- ROS homeostasis and metabolism: a dangerous liason in cancer cells
- (2016) E Panieri et al. Cell Death & Disease
- Keap1–Nrf2 signalling in pancreatic cancer
- (2015) Alastair J. Hayes et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Role of lipid peroxidation derived 4-hydroxynonenal (4-HNE) in cancer: Focusing on mitochondria
- (2015) Huiqin Zhong et al. Redox Biology
- Modulation of oxidative stress as an anticancer strategy
- (2013) Chiara Gorrini et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting the hallmarks of cancer
- (2012) Pierre Hainaut et al. CURRENT OPINION IN ONCOLOGY
- An Antioxidant Response Phenotype Shared between Hereditary and Sporadic Type 2 Papillary Renal Cell Carcinoma
- (2011) Aikseng Ooi et al. CANCER CELL
- Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
- (2011) Julie Adam et al. CANCER CELL
- Targeting cancer metabolism: a therapeutic window opens
- (2011) Matthew G. Vander Heiden NATURE REVIEWS DRUG DISCOVERY
- Glutathione S-transferases: an overview in cancer research
- (2010) Giuliano Di Pietro et al. Expert Opinion on Drug Metabolism & Toxicology
- Activation of NRF2 by Nitrosative Agents and H2O2Involves KEAP1 Disulfide Formation
- (2010) Simon Fourquet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk
- (2009) Irena E. Andonova et al. BREAST CANCER RESEARCH AND TREATMENT
- Effect of liver cirrhosis on phenylalanine and tyrosine metabolism
- (2009) Paolo Tessari et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1 Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species
- (2009) S. Sudarshan et al. MOLECULAR AND CELLULAR BIOLOGY
- Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development
- (2008) Silke Marhenke et al. HEPATOLOGY
- Real-time imaging of the intracellular glutathione redox potential
- (2008) Marcus Gutscher et al. NATURE METHODS
- Rescue from neonatal death in the murine model of hereditary tyrosinemia by glutathione monoethylester and vitamin C treatment
- (2007) Chantale Langlois et al. MOLECULAR GENETICS AND METABOLISM
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started