Astrocyte elevated gene 1 (AEG‐1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma

MicroRNA-30a suppresses autophagy-mediated anoikis resistance and metastasis in hepatocellular carcinoma

(2018) Xiu-Tao Fu et al.   CANCER LETTERS

New anti-cancer molecules targeting HSPA5/BIP to induce endoplasmic reticulum stress, autophagy and apoptosis

(2016) Michaël Cerezo et al.   Autophagy

Tetraspanin 8 mediates AEG-1-induced invasion and metastasis in hepatocellular carcinoma cells

(2016) Maaged A. Akiel et al.   FEBS LETTERS

Autophagy Induction Results in Enhanced Anoikis Resistance in Models of Peritoneal Disease

(2016) James L. Chen et al.   MOLECULAR CANCER RESEARCH

Autophagy in cancer metastasis

(2016) E E Mowers et al.   ONCOGENE

Lithocholic acid induces endoplasmic reticulum stress, autophagy and mitochondrial dysfunction in human prostate cancer cells

(2016) Ahmed A. Gafar et al.   PeerJ

A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy

(2015) Shane Deegan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Astrocyte elevated gene-1(AEG-1) induces epithelial-mesenchymal transition in lung cancer through activating Wnt/β-catenin signaling

(2015) Weiling He et al.   BMC CANCER

Astrocyte elevated gene-1 and c-Myc cooperate to promote hepatocarcinogenesis in mice

(2015) Jyoti Srivastava et al.   HEPATOLOGY

ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis

(2015) Souvik Dey et al.   JOURNAL OF CLINICAL INVESTIGATION

AEG-1 Promotes Metastasis Through Downstream AKR1C2 and NF1 in Liver Cancer

(2015) Cong Li et al.   ONCOLOGY RESEARCH

Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate

(2015) Z Liu et al.   Cell Death & Disease

MTDH-SND1 Interaction Is Crucial for Expansion and Activity of Tumor-Initiating Cells in Diverse Oncogene- and Carcinogen-Induced Mammary Tumors

(2014) Liling Wan et al.   CANCER CELL

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

Activin A induces growth arrest through a SMAD- dependent pathway in hepatic progenitor cells

(2014) Lin Chen et al.   Cell Communication and Signaling

Upregulation of BNIP3 mediated by ERK/HIF-1α pathway induces autophagy and contributes to anoikis resistance of hepatocellular carcinoma cells

(2014) Lei Sun et al.   Future Oncology

AEG-1 Promotes Anoikis Resistance and Orientation Chemotaxis in Hepatocellular Carcinoma Cells

(2014) Zhenzhen Zhou et al.   PLoS One

Is BMF central for anoikis and autophagy?

(2013) Monica Delgado et al.   Autophagy

Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells

(2013) Yuan-Fei Peng et al.   Autophagy

CD44s signals the acquisition of the mesenchymal phenotype required for anchorage-independent cell survival in hepatocellular carcinoma

(2013) H Okabe et al.   BRITISH JOURNAL OF CANCER

Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling

(2013) Ze-yang Ding et al.   CELLULAR SIGNALLING

Mechanisms that link the oncogenic epithelial–mesenchymal transition to suppression of anoikis

(2013) Steven M. Frisch et al.   JOURNAL OF CELL SCIENCE

Insulin-like Growth Factor-binding Protein-7 (IGFBP7); A Promising Gene Therapeutic for Hepatocellular Carcinoma (HCC)

(2013) Dong Chen et al.   MOLECULAR THERAPY

Role of Intracellular Calcium in Proteasome Inhibitor-Induced Endoplasmic Reticulum Stress, Autophagy, and Cell Death

(2013) Jessica A. Williams et al.   PHARMACEUTICAL RESEARCH

Astrocyte elevated gene-1 is a novel biomarker of epithelial–mesenchymal transition and progression of hepatocellular carcinoma in two China regions

(2013) Jiasheng Zheng et al.   TUMOR BIOLOGY

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

(2012) Shane Deegan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hepatitis B Virus X Protein Confers Resistance of Hepatoma Cells to Anoikis by Up-regulating and Activating p21-Activated Kinase 1

(2012) Jiejie Xu et al.   GASTROENTEROLOGY

Multifunction Protein Staphylococcal Nuclease Domain Containing 1 (SND1) Promotes Tumor Angiogenesis in Human Hepatocellular Carcinoma through Novel Pathway That Involves Nuclear Factor κB and miR-221

(2012) Prasanna Kumar Santhekadur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK

(2012) A Avivar-Valderas et al.   ONCOGENE

The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

(2012) B Luo et al.   ONCOGENE

The regulation of cancer cell death and metabolism by extracellular matrix attachment

(2012) Cassandra L. Buchheit et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Acquisition of anoikis resistance through CD147 upregulation: A new mechanism underlying metastasis of hepatocellular carcinoma cells

(2012) XIA KE et al.   Oncology Letters

PERK Integrates Autophagy and Oxidative Stress Responses To Promote Survival during Extracellular Matrix Detachment

(2011) A. Avivar-Valderas et al.   MOLECULAR AND CELLULAR BIOLOGY

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo

(2011) X-X He et al.   ONCOGENE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Astrocyte elevated gene 1: biological functions and molecular mechanism in cancer and beyond

(2011) Zhe Ying et al.   Cell and Bioscience

Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma

(2010) B. K. Yoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression

(2009) Byoung Kwon Yoo et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular matrix regulation of autophagy

(2008) Rebecca Lock et al.   CURRENT OPINION IN CELL BIOLOGY

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL