Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate

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A Drosophila model of combined D-2- and L-2-hydroxyglutaric aciduria reveals a mechanism linking mitochondrial citrate export with oncometabolite accumulation

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Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

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L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration

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Drosophilalarvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth

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Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions

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2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

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Mitochondrial retrograde signaling regulates neuronal function

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Drosophila melanogaster Activating Transcription Factor 4 Regulates Glycolysis During Endoplasmic Reticulum Stress

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Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease

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TFAM forces mtDNA to make a U-turn

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