Anticancer activity, DNA binding and cell mechanistic studies of estrogen-functionalised Cu(II) complexes

Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?

(2019) Reece G. Kenny et al.   CHEMICAL REVIEWS

Synthesis, characterisation and in vitro antitumour potential of novel Pt(II) estrogen linked complexes

(2019) Eolann Kitteringham et al.   INORGANICA CHIMICA ACTA

Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes

(2018) Stephen Barrett et al.   INORGANICA CHIMICA ACTA

Di-copper metallodrugs promote NCI-60 chemotherapy via singlet oxygen and superoxide production with tandem TA/TA and AT/AT oligonucleotide discrimination

(2018) Creina Slator et al.   NUCLEIC ACIDS RESEARCH

Ex Vivo Cardiotoxicity of Antineoplastic Casiopeinas Is Mediated through Energetic Dysfunction and Triggered Mitochondrial-Dependent Apoptosis

(2018) Christian Silva-Platas et al.   Oxidative Medicine and Cellular Longevity

Polypyridyl-based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease

(2018) Nicolo Zuin Fantoni et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Innovative DNA-Targeted Metallo-Prodrug Strategy combining Histone Deacetylase Inhibition with Oxidative Stress

(2018) Tadhg J.P. McGivern et al.   MOLECULAR PHARMACEUTICS

A phosphate-targeted dinuclear Cu(II) complex combining major groove binding and oxidative DNA cleavage

(2018) Zara Molphy et al.   NUCLEIC ACIDS RESEARCH

Correction: Metformin reveals a mitochondrial copper addiction of mesenchymal cancer cells

(2018) Sebastian Müller et al.   PLoS One

Anticancer activity of a series of copper(II) complexes with tripodal ligands

(2017) Melanie Jopp et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of DNA/Protein interactions and cytotoxic studies of copper(II) complexes incorporated with N, N donor ligands and terpyridine ligand

(2017) Kiran Tummalapalli et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis, characterization, X-ray structures, and biological activity of some metal complexes of the Schiff base 2,2′-(((azanediylbis(propane-3,1-diyl))bis(azanylylidene))bis(methanylylidene))diphenol

(2015) Noureddine Charef et al.   POLYHEDRON

Steric vs electronic effects and solvent coordination in the electrochemistry of phenanthroline-based copper complexes

(2014) Mirko Magni et al.   ELECTROCHIMICA ACTA

Structural and Electrochemical Studies of Copper(I) Complexes with Diethoxyphosphoryl-1,10-phenanthrolines

(2014) Alexander Mitrofanov et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Copper Phenanthrene Oxidative Chemical Nucleases

(2014) Zara Molphy et al.   INORGANIC CHEMISTRY

A new phenanthroline–oxazine ligand: synthesis, coordination chemistry and atypical DNA binding interaction

(2013) Malachy McCann et al.   CHEMICAL COMMUNICATIONS

Synthesis of Transition-Metal Steroid Derivatives

(2013) Franck Le Bideau et al.   CHEMICAL REVIEWS

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation

(2012) Cristina Trejo-Solís et al.   BMC CANCER

In vitro cytotoxicity, DNA cleavage and SOD-mimic activity of copper(II) mixed-ligand quinolinonato complexes

(2012) Roman Buchtík et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Crystal structures of Λ-[Ru(phen)2dppz]2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes

(2012) Hakan Niyazi et al.   Nature Chemistry

Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissues

(2011) Pijus Saha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Characterization of 2′-deoxyguanosine oxidation products observed in the Fenton-like system Cu(ii)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts

(2011) Aaron M. Fleming et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(ii) metallo-drug

(2010) Martin Huxley et al.   DALTON TRANSACTIONS

Conjugation of testosterone modifies the interaction of mono-functional cationic platinum(ii) complexes with DNA, causing significant alterations to the DNA helix

(2010) Carlos Sanchez-Cano et al.   DALTON TRANSACTIONS

Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: Comparative molecular modeling study of three distinct families of hybrids

(2010) Josée Provencher-Mandeville et al.   STEROIDS

Cytotoxicity of the traditional chinese medicine (TCM) plumbagin in its copper chemistry

(2009) Zhen-Feng Chen et al.   DALTON TRANSACTIONS

Thiosemicarbazones from the Old to New: Iron Chelators That Are More Than Just Ribonucleotide Reductase Inhibitors

(2009) Yu Yu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 17β-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell lines

(2008) Josée Provencher-Mandeville et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS