Roseltide rT7 is a disulfide-rich, anionic, and cell-penetrating peptide that inhibits proteasomal degradation

Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics

(2019) Antony Kam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation

(2019) Monique Bax et al.   Cells

Getting in: emerging methods and design principles for cell-penetrant peptides

(2018) Leila Peraro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and Function of the 26S Proteasome

(2018) Jared A.M. Bard et al.   Annual Review of Biochemistry

A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L.

(2018) Ghazala Riaz et al.   BIOMEDICINE & PHARMACOTHERAPY

Ginsentides: Cysteine and Glycine-rich Peptides from the Ginseng Family with Unusual Disulfide Connectivity

(2018) James P. Tam et al.   Scientific Reports

Proteasome Structure and Assembly

(2017) Lauren Budenholzer et al.   JOURNAL OF MOLECULAR BIOLOGY

The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

(2017) Yong Tae Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES

Immunoproteasome functions explained by divergence in cleavage specificity and regulation

(2017) Michael B Winter et al.   eLife

Bleogens: Cactus-Derived Anti-Candida Cysteine-Rich Peptides with Three Different Precursor Arrangements

(2017) Shining Loo et al.   Frontiers in Plant Science

Plant cystine-knot peptides: pharmacological perspectives

(2016) Barbara Molesini et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking

(2016) Xinxin Gao et al.   Scientific Reports

Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa

(2016) Shining Loo et al.   Scientific Reports

Antiviral Cystine Knot α-Amylase Inhibitors fromAlstonia scholaris

(2015) Phuong Quoc Thuc Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors

(2015) Eva M. Huber et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

Disulfide-rich macrocyclic peptides as templates in drug design

(2014) Susan E. Northfield et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Gallic acid protects against endothelial injury by restoring the depletion of DNA methyltransferase 1 and inhibiting proteasome activities

(2013) Antony Kam et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

(2013) Yanbin Ji et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orally Active Peptidic Bradykinin B1 Receptor Antagonists Engineered from a Cyclotide Scaffold for Inflammatory Pain Treatment

(2012) Clarence T. T. Wong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Covalent and non-covalent reversible proteasome inhibition

(2012) Philipp Beck et al.   BIOLOGICAL CHEMISTRY

The Carmaphycins: New Proteasome Inhibitors Exhibiting an α,β-Epoxyketone Warhead from a Marine Cyanobacterium

(2012) Alban R. Pereira et al.   CHEMBIOCHEM

CyLoP-1: A Novel Cysteine-Rich Cell-Penetrating Peptide for Cytosolic Delivery of Cargoes

(2011) Deepti Jha et al.   BIOCONJUGATE CHEMISTRY

Exploiting nature's rich source of proteasome inhibitors as starting points in drug development

(2011) Melissa Ann Gräwert et al.   CHEMICAL COMMUNICATIONS

Bioactive cystine knot proteins

(2011) Norelle L Daly et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Antimicrobial peptides with cell-penetrating peptide properties and vice versa

(2011) Katrin Splith et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Tying the knot: The cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines

(2011) Shalini Iyer et al.   FEBS Journal

Identification and Characterization of a New Family of Cell-penetrating Peptides

(2011) Laura Cascales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunit

(2010) Christopher Blackburn et al.   BIOCHEMICAL JOURNAL

Cystine-knot peptides engineered with specificities for αIIbβ3 or αIIbβ3 and αvβ3 integrins are potent inhibitors of platelet aggregation

(2010) Adam P. Silverman et al.   JOURNAL OF MOLECULAR RECOGNITION

Cyclotides as templates in drug design

(2009) Sónia Troeira Henriques et al.   DRUG DISCOVERY TODAY

Inhibition of the 20S Proteosome by a Protein Proteinase Inhibitor: Evidence That a Natural Serine Proteinase Inhibitor Can Inhibit a Threonine Proteinase

(2008) K. Yabe et al.   JOURNAL OF BIOCHEMISTRY

Engineering Stabilized Vascular Endothelial Growth Factor-A Antagonists: Synthesis, Structural Characterization, and Bioactivity of Grafted Analogues of Cyclotides

(2008) Sunithi Gunasekera et al.   JOURNAL OF MEDICINAL CHEMISTRY