Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift

(2018) Jane A. Armstrong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bleogens: Cactus-Derived Anti-Candida Cysteine-Rich Peptides with Three Different Precursor Arrangements

(2017) Shining Loo et al.   Frontiers in Plant Science

Glycosaminoglycans are required for translocation of amphipathic cell-penetrating peptides across membranes

(2016) Janely Pae et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization

(2016) Wen Yang et al.   CELL

Immunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea)

(2016) Kim Ngan T. Nguyen et al.   FEBS Journal

Mitochondria targeting nano agents in cancer therapeutics

(2016) Xiao-Ying Zhang et al.   Oncology Letters

Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa

(2016) Shining Loo et al.   Scientific Reports

Allotides: Proline-Rich Cystine Knot α-Amylase Inhibitors from Allamanda cathartica

(2015) Phuong Q. T. Nguyen et al.   JOURNAL OF NATURAL PRODUCTS

Discovery and characterization of pseudocyclic cystine-knot α-amylase inhibitors with high resistance to heat and proteolytic degradation

(2014) Phuong Q. T. Nguyen et al.   FEBS Journal

Mitochondria and Metabolic Homeostasis

(2013) Zhiyong Cheng et al.   ANTIOXIDANTS & REDOX SIGNALING

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

The Future of Peptide-based Drugs

(2012) David J. Craik et al.   Chemical Biology & Drug Design

Mitochondrial Control of Cellular Life, Stress, and Death

(2012) Lorenzo Galluzzi et al.   CIRCULATION RESEARCH

Biological Activities of Natural and Engineered Cyclotides, a Novel Molecular Scaffold for Peptide-Based Therapeutics

(2012) Angie E. Garcia et al.   Current Molecular Pharmacology

Emerging nanomaterials for targeting subcellular organelles

(2011) Jasper G. Huang et al.   Nano Today

Therapy for mitochondrial disorders: Little proof, high research activity, some promise

(2011) Anu Suomalainen   Seminars in Fetal & Neonatal Medicine

Cyclotides, a promising molecular scaffold for peptide-based therapeutics

(2010) Krishnappa Jagadish et al.   BIOPOLYMERS

Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria?

(2010) E. M. V. de Cavanagh et al.   CARDIOVASCULAR RESEARCH

Impaired quality control of mitochondria: Aging from a new perspective

(2010) Tobias A. Weber et al.   EXPERIMENTAL GERONTOLOGY

Neuroprotective strategies involving ROS in Alzheimer disease

(2010) Magali Dumont et al.   FREE RADICAL BIOLOGY AND MEDICINE

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

Dual role of the receptor Tom20 in specificity and efficiency of protein import into mitochondria

(2010) H. Yamamoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria-Penetrating Peptides: Sequence Effects and Model Cargo Transport

(2009) Lema F. Yousif et al.   CHEMBIOCHEM

Targeting Mitochondria with Organelle-Specific Compounds: Strategies and Applications

(2009) Lema F. Yousif et al.   CHEMBIOCHEM

Mitochondria: Determinants of Stem Cell Fate?

(2009) Graham C. Parker et al.   STEM CELLS AND DEVELOPMENT

Mitochondria-Penetrating Peptides

(2008) Kristin L. Horton et al.   CHEMISTRY & BIOLOGY

Conus Venoms - A Rich Source of Peptide-Based Therapeutics

(2008) Tiffany Han et al.   CURRENT PHARMACEUTICAL DESIGN

The cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activities

(2008) Alexander Kloß et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS