Formation of biological condensates via phase separation: Characteristics, analytical methods, and physiological implications
出版年份 2019 全文链接
标题
Formation of biological condensates via phase separation: Characteristics, analytical methods, and physiological implications
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 294, Issue 40, Pages 14823-14835
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2019-08-24
DOI
10.1074/jbc.rev119.007895
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons
- (2019) Jean-Michel Cioni et al. CELL
- RIM and RIM-BP Form Presynaptic Active-Zone-like Condensates via Phase Separation
- (2019) Xiandeng Wu et al. MOLECULAR CELL
- A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS
- (2019) William Y. C. Huang et al. SCIENCE
- Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
- (2019) Lindsay B. Case et al. SCIENCE
- Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation
- (2019) Brian Tsang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease
- (2019) Natalia B. Nedelsky et al. Nature Reviews Neurology
- Rubisco condensate formation by CcmM in β-carboxysome biogenesis
- (2019) H. Wang et al. NATURE
- Matter over mind: Liquid phase separation and neurodegeneration
- (2019) Shana Elbaum-Garfinkle JOURNAL OF BIOLOGICAL CHEMISTRY
- Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
- (2019) Simon Alberti et al. CELL
- Regulation of Transmembrane Signaling by Phase Separation
- (2019) Lindsay B. Case et al. Annual Review of Biophysics
- Phase Separation and the Centrosome: A Fait Accompli?
- (2019) Jordan W. Raff TRENDS IN CELL BIOLOGY
- Temperature, Hydrostatic Pressure, and Osmolyte Effects on Liquid-Liquid Phase Separation in Protein Condensates: Physical Chemistry and Biological Implications
- (2019) Roland Hermann Alfons Winter et al. CHEMISTRY-A EUROPEAN JOURNAL
- Physical Principles and Extant Biology Reveal Roles for RNA-Containing Membraneless Compartments in Origins of Life Chemistry
- (2018) Raghav R. Poudyal et al. BIOCHEMISTRY
- Theories for Sequence-Dependent Phase Behaviors of Biomolecular Condensates
- (2018) Yi-Hsuan Lin et al. BIOCHEMISTRY
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
- (2018) Seema Qamar et al. CELL
- RGG/RG Motif Regions in RNA Binding and Phase Separation
- (2018) P. Andrew Chong et al. JOURNAL OF MOLECULAR BIOLOGY
- Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation
- (2018) Veronica H. Ryan et al. MOLECULAR CELL
- Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
- (2018) Michael P. Hughes et al. SCIENCE
- DNA-induced liquid phase condensation of cGAS activates innate immune signaling
- (2018) Mingjian Du et al. SCIENCE
- A liquid phase of synapsin and lipid vesicles
- (2018) Dragomir Milovanovic et al. SCIENCE
- Protein Phase Separation: A New Phase in Cell Biology
- (2018) Steven Boeynaems et al. TRENDS IN CELL BIOLOGY
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity
- (2018) Menglong Zeng et al. CELL
- mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation
- (2018) Gangming Zhang et al. CELL
- Spatiotemporal regulation of liquid-like condensates in epigenetic inheritance
- (2018) Gang Wan et al. NATURE
- Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
- (2018) Claudio Soto et al. NATURE NEUROSCIENCE
- Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases
- (2018) Mathias Jucker et al. NATURE NEUROSCIENCE
- Converging pathways in neurodegeneration, from genetics to mechanisms
- (2018) Li Gan et al. NATURE NEUROSCIENCE
- A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions
- (2018) Weirui Ma et al. CELL
- Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
- (2017) Yuan Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
- (2017) Steven Boeynaems et al. MOLECULAR CELL
- RNA phase transitions in repeat expansion disorders
- (2017) Ankur Jain et al. NATURE
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Liquid phase condensation in cell physiology and disease
- (2017) Yongdae Shin et al. SCIENCE
- Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
- (2017) Susmitha Ambadipudi et al. Nature Communications
- Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity
- (2016) Menglong Zeng et al. CELL
- The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules
- (2016) Hao Wu et al. CELL
- Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism
- (2016) Shambaditya Saha et al. CELL
- Coexisting Liquid Phases Underlie Nucleolar Subcompartments
- (2016) Marina Feric et al. CELL
- Decoding ALS: from genes to mechanism
- (2016) J. Paul Taylor et al. NATURE
- Phase separation of signaling molecules promotes T cell receptor signal transduction
- (2016) Xiaolei Su et al. SCIENCE
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA
- (2016) Diana M Mitrea et al. eLife
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- RNA Controls PolyQ Protein Phase Transitions
- (2015) Huaiying Zhang et al. MOLECULAR CELL
- Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
- (2015) Yuan Lin et al. MOLECULAR CELL
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
- (2015) Tetsuro Murakami et al. NEURON
- The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
- (2015) Shana Elbaum-Garfinkle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulated assembly of a supramolecular centrosome scaffold in vitro
- (2015) J. B. Woodruff et al. SCIENCE
- Liquid-Liquid Phase Separation in Biology
- (2014) Anthony A. Hyman et al. Annual Review of Cell and Developmental Biology
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phase transitions of multivalent proteins can promote clustering of membrane receptors
- (2014) Sudeep Banjade et al. eLife
- RNA Seeds Higher-Order Assembly of FUS Protein
- (2013) Jacob C. Schwartz et al. Cell Reports
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies
- (2012) Tina W. Han et al. CELL
- Phase transitions in the assembly of multivalent signalling proteins
- (2012) Pilong Li et al. NATURE
- Mechanisms of CaMKII action in long-term potentiation
- (2012) John Lisman et al. NATURE REVIEWS NEUROSCIENCE
- P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation
- (2012) C. J. Decker et al. Cold Spring Harbor Perspectives in Biology
- Phase Separation in Lipid Membranes
- (2011) F. A. Heberle et al. Cold Spring Harbor Perspectives in Biology
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
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