期刊
BIOMATERIALS
卷 103, 期 -, 页码 278-292出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biomaterials.2016.07.001
关键词
Heart valves; Tissue engineering; Nanotechnologies; Microtechnologies; Scaffolds; Hydrogels
资金
- Natural Sciences and Engineering Research of Canada
- Qatar Foundation [NPRP9-144-3-021]
- Qatar University [QUUG-CENG-MIE-15/16-7, QUST-CENG-FALL-15/16-20]
- American University of Beirut
- CNRS from National Council for Scientific Research, Lebanon
Due to the increased morbidity and mortality resulting from heart valve diseases, there is a growing demand for off-the-shelf implantable tissue engineered heart valves (TEHVs). Despite the significant progress in recent years in improving the design and performance of TEHV constructs, viable and functional human implantable TEHV constructs have remained elusive. The recent advances in micro and nanoscale technologies including the microfabrication, nano-microfiber based scaffolds preparation, 3D cell encapsulated hydrogels preparation, microfluidic, micro-bioreactors, nano-microscale biosensors as well as the computational methods and models for simulation of biological tissues have increased the potential for realizing viable, functional and implantable TEHV constructs. In this review, we aim to present an overview of the importance and recent advances in micro and nano-scale technologies for the development of TEHV constructs. (C) 2016 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据