αvβ3 integrins negatively regulate cellular forces by phosphorylation of its distal NPXY site

Contributions of the integrin β1 tail to cell adhesive forces

(2015) Imen Elloumi-Hannachi et al.   EXPERIMENTAL CELL RESEARCH

The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions

(2015) H. E. Balcioglu et al.   JOURNAL OF CELL SCIENCE

Extracellular rigidity sensing by talin isoform-specific mechanical linkages

(2015) Katharina Austen et al.   NATURE CELL BIOLOGY

Forcing cells into shape: the mechanics of actomyosin contractility

(2015) Michael Murrell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Adaptive rheology and ordering of cell cytoskeleton govern matrix rigidity sensing

(2015) Mukund Gupta et al.   Nature Communications

Vinculin controls talin engagement with the actomyosin machinery

(2015) Paul Atherton et al.   Nature Communications

Hydrogel Micropillars with Integrin Selective Peptidomimetic Functionalized Nanopatterned Tops: A New Tool for the Measurement of Cell Traction Forces Transmitted through αvβ3- or α5β1-Integrins

(2013) Sabri Rahmouni et al.   ADVANCED MATERIALS

The Mechanism of Kindlin-Mediated Activation of Integrin αIIbβ3

(2013) Feng Ye et al.   CURRENT BIOLOGY

Activation of beta 1 but not beta 3 integrin increases cell traction forces

(2013) Grace L. Lin et al.   FEBS LETTERS

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

(2012) Laura M. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions

(2012) Olivier Rossier et al.   NATURE CELL BIOLOGY

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Regulation of Integrin Activation

(2011) Chungho Kim et al.   Annual Review of Cell and Developmental Biology

A zyxin–nectin interaction facilitates zyxin localization to cell–cell adhesions

(2011) S. Gregory Call et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Kindlin

(2011) Feng Ye et al.   CURRENT OPINION IN HEMATOLOGY

Integrin  5 1 facilitates cancer cell invasion through enhanced contractile forces

(2011) C. T. Mierke et al.   JOURNAL OF CELL SCIENCE

The Mechanical Role of VASP in an Arp2/3-Complex-Based Motility Assay

(2011) Sandy Suei et al.   JOURNAL OF MOLECULAR BIOLOGY

A new micropatterning method of soft substrates reveals that different tumorigenic signals can promote or reduce cell contraction levels

(2011) Qingzong Tseng et al.   LAB ON A CHIP

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Affinity of talin-1 for the  3-integrin cytosolic domain is modulated by its phospholipid bilayer environment

(2011) D. T. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Zyxin-Mediated Mechanism for Actin Stress Fiber Maintenance and Repair

(2010) Mark A. Smith et al.   DEVELOPMENTAL CELL

Tyrosine Phosphorylation of Integrin β3Regulates Kindlin-2 Binding and Integrin Activation

(2010) Kamila Bledzka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vinculin Facilitates Cell Invasion into Three-dimensional Collagen Matrices

(2010) Claudia T. Mierke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin β3Phosphorylation Dictates Its Complex with the Shc Phosphotyrosine-binding (PTB) Domain

(2010) Lalit Deshmukh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration

(2010) Daniel C. Worth et al.   JOURNAL OF CELL BIOLOGY

β1A Integrin Is a Master Regulator of Invadosome Organization and Function

(2010) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

(2009) Nicholas J Anthis et al.   EMBO JOURNAL

Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

(2009) David S. Harburger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms that regulate adaptor binding to  -integrin cytoplasmic tails

(2009) K. R. Legate et al.   JOURNAL OF CELL SCIENCE

Clustering of  5 1 integrins determines adhesion strength whereas  v 3 and talin enable mechanotransduction

(2009) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A zyxin head–tail interaction regulates zyxin–VASP complex formation

(2008) James D. Moody et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Integrin-mediated Protein Kinase A Activation at the Leading Edge of Migrating Cells

(2008) Chinten J. Lim et al.   MOLECULAR BIOLOGY OF THE CELL

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

(2008) Xian Zhang et al.   NATURE CELL BIOLOGY

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biomechanical regulation of cell orientation and fate

(2008) J I Lopez et al.   ONCOGENE

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE

Matrix Elasticity, Cytoskeletal Tension, and TGF- : The Insoluble and Soluble Meet

(2008) R. G. Wells et al.   Science Signaling