Why Is Tetradentate Coordination Essential for Potential Copper Homeostasis Regulators in Alzheimer's Disease?

The TDMQ Regulators of Copper Homeostasis Do Not Disturb the Activities of Cu,Zn-SOD, Tyrosinase, or the CoIII Cofactor Vitamin B12

(2019) Ju Huang et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Metal Ions in Alzheimer’s Disease: A Key Role or Not?

(2019) Yan Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

N4 -Tetradentate Chelators Efficiently Regulate Copper Homeostasis and Prevent ROS Production Induced by Copper-Amyloid-β1-16

(2018) Weixin Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Preparation of Tetradentate Copper Chelators as Potential Anti-Alzheimer Agents

(2018) Weixin Zhang et al.   ChemMedChem

Structures of the Copper and Zinc Complexes of PBT2, a Chelating Agent Evaluated as Potential Drug for Neurodegenerative Diseases

(2017) Michel Nguyen et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Chelation of hippocampal zinc enhances long-term potentiation and synaptic tagging/capture in CA1 pyramidal neurons of aged rats: implications to aging and memory

(2016) Mahesh Shivarama Shetty et al.   AGING CELL

Regulation of Copper and Iron Homeostasis by Metal Chelators: A Possible Chemotherapy for Alzheimer’s Disease

(2015) Anne Robert et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transfer of Copper from an Amyloid to a Natural Copper-Carrier Peptide with a Specific Mediating Ligand

(2015) Michel Nguyen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Biological metals and metal-targeting compounds in major neurodegenerative diseases

(2014) Kevin J. Barnham et al.   CHEMICAL SOCIETY REVIEWS

Characterization of New Specific Copper Chelators as Potential Drugs for the Treatment of Alzheimer’s Disease

(2014) Michel Nguyen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress

(2012) Rudy J. Castellani et al.   ARCHIVES OF MEDICAL RESEARCH

Synthesis, Thermal and Spectroscopic Characterization of Caq2 (Calcium 8-Hydroxyquinoline) Organic Phosphor

(2012) I. M. Nagpure et al.   JOURNAL OF FLUORESCENCE

Copper Chelator Induced Efficient Episodic Memory Recovery in a Non-Transgenic Alzheimer’s Mouse Model

(2012) Johnatan Ceccom et al.   PLoS One

Minding metals: Tailoring multifunctional chelating agents for neurodegenerative disease

(2009) Lissette R. Perez et al.   DALTON TRANSACTIONS

Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+

(2009) D. A. Andersson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

(2008) Paul A. Adlard et al.   NEURON