HDAC5-mediated deacetylation and nuclear localisation of SOX9 is critical for tamoxifen resistance in breast cancer

Embryonic transcription factor SOX9 drives breast cancer endocrine resistance

(2017) Rinath Jeselsohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells

(2017) Wen-Tsung Huang et al.   Frontiers in Pharmacology

Acetylation reduces SOX9 nuclear entryand ACANgene transactivation in human chondrocytes

(2016) Michal Bar Oz et al.   AGING CELL

FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis

(2016) Lin Shan et al.   CANCER CELL

SOX9 and the many facets of its regulation in the chondrocyte lineage

(2016) Véronique Lefebvre et al.   CONNECTIVE TISSUE RESEARCH

Sox9 regulates self-renewal and tumorigenicity by promoting symmetrical cell division of cancer stem cells in hepatocellular carcinoma

(2016) Chungang Liu et al.   HEPATOLOGY

PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6

(2016) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression

(2016) C Cao et al.   ONCOGENE

AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol

(2015) Shuyang Chen et al.   CELL CYCLE

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion

(2015) Jean-Christophe Larsimont et al.   Cell Stem Cell

Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion

(2015) Diane Ojo et al.   CURRENT MEDICINAL CHEMISTRY

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression

(2015) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

HOXB7 Is an ER  Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance

(2015) K. Jin et al.   Cancer Discovery

MicroRNA-320a sensitizes tamoxifen-resistant breast cancer cells to tamoxifen by targeting ARPP-19 and ERRγ*

(2015) Mingrong Lü et al.   Scientific Reports

The SOX Transcription Factors as Key Players in Pluripotent Stem Cells

(2014) Essam M. Abdelalim et al.   STEM CELLS AND DEVELOPMENT

Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells

(2013) Shauna N. Vasilatos et al.   CARCINOGENESIS

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

The SOX family of genes in cancer development: biological relevance and opportunities for therapy

(2012) Sandra D Castillo et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells

(2011) Yi Huang et al.   BREAST CANCER RESEARCH AND TREATMENT

Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment

(2011) Geetika Chakravarty et al.   CANCER BIOLOGY & THERAPY

Prognostic significance of cytoplasmic SOX9 in invasive ductal carcinoma and metastatic breast cancer

(2011) Geetika Chakravarty et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells

(2009) C. Urbich et al.   BLOOD

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Sox9 Family Members Negatively Regulate Maturation and Calcification of Chondrocytes through Up-Regulation of Parathyroid Hormone–related Protein

(2009) Katsuhiko Amano et al.   MOLECULAR BIOLOGY OF THE CELL

SnapShot: p53 Posttranslational Modifications

(2008) Jan-Philipp Kruse et al.   CELL

Regulation of Cartilage-specific Gene Expression in Human Chondrocytes by SirT1 and Nicotinamide Phosphoribosyltransferase

(2008) Mona Dvir-Ginzberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specific Activity of Class II Histone Deacetylases in Human Breast Cancer Cells

(2008) V. Duong et al.   MOLECULAR CANCER RESEARCH

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY