Complement C3a induces axonal hypomyelination in the periventricular white matter through activation of WNT/β‐catenin signal pathway in septic neonatal rats experimentally induced by lipopolysaccharide

Complement targets newborn retinal ganglion cells for phagocytic elimination by microglia

(2019) Sarah R Anderson et al.   JOURNAL OF NEUROSCIENCE

Does bovine lactoferrin prevent late-onset neonatal sepsis?

(2019) Lex W Doyle et al.   LANCET

Antidepressive effects of kaempferol mediated by reduction of oxidative stress, proinflammatory cytokines and up-regulation of AKT/β-catenin cascade

(2019) Wenqi Gao et al.   METABOLIC BRAIN DISEASE

Complement C3a receptor antagonist attenuates tau hyperphosphorylation via glycogen synthase kinase 3β signaling pathways

(2019) Junjie Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer’s disease

(2019) Dawling A. Dionisio-Santos et al.   Journal of Neuroinflammation

Molecular Control of Oligodendrocyte Development

(2019) Benayahu Elbaz et al.   TRENDS IN NEUROSCIENCES

Revisiting the role of the innate immune complement system in ALS

(2019) Sandra E. Parker et al.   NEUROBIOLOGY OF DISEASE

Heterogeneity of Microglia Phenotypes: Developmental, Functional and Some Therapeutic Considerations

(2019) Yun Yuan et al.   CURRENT PHARMACEUTICAL DESIGN

Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination

(2018) Giusy T. Coppolino et al.   GLIA

LGR5 and BMI1 Increase Pig Intestinal Epithelial Cell Proliferation by Stimulating WNT/β-Catenin Signaling

(2018) Xiang-Guang Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Teriflunomide promotes oligodendroglial differentiation and myelination

(2018) Peter Göttle et al.   Journal of Neuroinflammation

Inhibition of WNT/β-catenin signaling under serum starvation and hypoxia induces adipocytic transdifferentiation in human leiomyoma cells

(2018) Hiroshi Harada et al.   LABORATORY INVESTIGATION

Glycogen synthase kinase-3β inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A

(2018) Preeti Dohare et al.   NEUROBIOLOGY OF DISEASE

Neural stem cell differentiation into mature neurons: Mechanisms of regulation and biotechnological applications

(2018) Mariana S. Vieira et al.   BIOTECHNOLOGY ADVANCES

Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models

(2018) Seline A. Zwarthoff et al.   Frontiers in Immunology

Release of astroglial vimentin by extracellular vesicles: Modulation of binding and internalization of C3 transferase in astrocytes and neurons

(2018) Andrej Adolf et al.   GLIA

Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese

(2018) Katriana A. Popichak et al.   Journal of Neuroinflammation

Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica

(2018) Tianjiao Duan et al.   Journal of Neuroinflammation

Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer’s Disease

(2018) Celia Luchena et al.   MEDIATORS OF INFLAMMATION

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

(2018) Borislav Dejanovic et al.   NEURON

Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease

(2018) Alexandra Litvinchuk et al.   NEURON

The adult oligodendrocyte can participate in remyelination

(2018) Ian D. Duncan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model

(2017) Eridan Rocha-Ferreira et al.   Journal of Neuroinflammation

Microglia-derived IL-1β contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats

(2017) Qianpeng Han et al.   Journal of Neuroinflammation

Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation

(2017) Anqi Xiong et al.   MATRIX BIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing

(2017) Miguel Crespo et al.   NATURE MEDICINE

Leishmania donovani inhibits macrophage apoptosis and pro-inflammatory response through AKT-mediated regulation of β-catenin and FOXO-1

(2016) Purnima Gupta et al.   CELL DEATH AND DIFFERENTIATION

Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain

(2016) Fengjiao Wu et al.   Journal of Neuroinflammation

Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination

(2016) Danyang He et al.   NATURE NEUROSCIENCE

Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation

(2016) Tao Deng et al.   NUCLEIC ACIDS RESEARCH

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

(2016) Chuntao Zhao et al.   Nature Communications

Association between preterm brain injury and exposure to chorioamnionitis during fetal life

(2016) Devasuda Anblagan et al.   Scientific Reports

Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination

(2015) Anna Preisner et al.   ACTA NEUROPATHOLOGICA

CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation

(2015) Mi-Yeon Kim et al.   GLIA

IL-1β induces hypomyelination in the periventricular white matter through inhibition of oligodendrocyte progenitor cell maturation via FYN/MEK/ERK signaling pathway in septic neonatal rats

(2015) Di Xie et al.   GLIA

White matter alterations of the corticospinal tract in adults born very preterm and/or with very low birth weight

(2015) Alina Jurcoane et al.   HUMAN BRAIN MAPPING

Schwann cells induce Proliferation and Migration of Oligodendrocyte Precursor Cells Through Secretion of PDGF-AA and FGF-2

(2015) Yue-Juan Chen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia

(2015) Alexandre Savard et al.   Journal of Neuroinflammation

The Wnt Effector Transcription Factor 7-Like 2 Positively Regulates Oligodendrocyte Differentiation in a Manner Independent of Wnt/ -Catenin Signaling

(2015) E. Hammond et al.   JOURNAL OF NEUROSCIENCE

Elevated plasma and cerebrospinal fluid interleukin-1 beta and tumor necrosis factor-alpha concentration and combined outcome of death or abnormal neuroimaging in preterm neonates with early-onset clinical sepsis

(2015) S Basu et al.   Journal of Perinatology

Visual–motor deficits relate to altered gray and white matter in young adults born preterm with very low birth weight

(2015) Kam Sripada et al.   NEUROIMAGE

NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease

(2015) Hong Lian et al.   NEURON

A novel β-catenin signaling pathway activated by IL-1β leads to the onset of epithelial–mesenchymal transition in breast cancer cells

(2014) Eloy Andres Perez-Yepez et al.   CANCER LETTERS

Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis

(2014) Tracy J. Yuen et al.   CELL

Early-Onset Neonatal Sepsis

(2014) K. A. Simonsen et al.   CLINICAL MICROBIOLOGY REVIEWS

Neonatal sepsis as a risk factor for neurodevelopmental changes in preterm infants with very low birth weight

(2014) Rachel C. Ferreira et al.   Jornal de Pediatria

TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain

(2014) Lan-Wan Wang et al.   Journal of Neuroinflammation

The immune response after hypoxia-ischemia in a mouse model of preterm brain injury

(2014) Anna-Maj Albertsson et al.   Journal of Neuroinflammation

Enterovirus infections are associated with white matter damage in neonates

(2014) Tai Wu et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Association of late-onset neonatal sepsis with late neurodevelopment in the first two years of life of preterm infants with very low birth weight

(2013) Cláudia Regina Hentges et al.   Jornal de Pediatria

Neurodevelopmental Outcome of Extremely Low Birth Weight Infants with Candida Infection

(2013) Ira Adams-Chapman et al.   JOURNAL OF PEDIATRICS

Neonatal Gram Negative and Candida Sepsis Survival and Neurodevelopmental Outcome at the Corrected Age of 24 Months

(2013) Timo R. de Haan et al.   PLoS One

Exogenous Leukemia Inhibitory Factor Stimulates Oligodendrocyte Progenitor Cell Proliferation and Enhances Hippocampal Remyelination

(2012) B. E. Deverman et al.   JOURNAL OF NEUROSCIENCE

White matter damage and neonatal sepsis

(2011) Nora Hofer et al.   ACTA PAEDIATRICA

Ibuprofen inhibits neuroinflammation and attenuates white matter damage following hypoxia–ischemia in the immature rodent brain

(2011) M.L. Carty et al.   BRAIN RESEARCH

Microglia-Derived Macrophage Colony Stimulating Factor Promotes Generation of Proinflammatory Cytokines by Astrocytes in the Periventricular White Matter in the Hypoxic Neonatal Brain

(2010) Yi Yu Deng et al.   BRAIN PATHOLOGY

Effect of the C3a-Receptor Antagonist SB 290157 on Anti-OVA Polyclonal Antibody–Induced Arthritis

(2010) Pilaiwanwadee Hutamekalin et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

CNS-specific expression of C3a and C5a exacerbate demyelination severity in the cuprizone model

(2010) Sarah A. Ingersoll et al.   MOLECULAR IMMUNOLOGY

Trends in the Rates of Cerebral Palsy Associated with Neonatal Intensive Care of Preterm Children

(2008) MAUREEN HACK et al.   CLINICAL OBSTETRICS AND GYNECOLOGY

C3a Receptor Antagonist Attenuates Brain Injury after Intracerebral Hemorrhage

(2008) Michal A Rynkowski et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM