Bacterial microcompartments: catalysis-enhancing metabolic modules for next generation metabolic and biomedical engineering

Glycyl Radical Enzyme-Associated Microcompartments: Redox-Replete Bacterial Organelles

(2019) Bryan Ferlez et al.   mBio

The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly

(2019) Basil J. Greber et al.   STRUCTURE

Rubisco condensate formation by CcmM in β-carboxysome biogenesis

(2019) H. Wang et al.   NATURE

A designed bacterial microcompartment shell with tunable composition and precision cargo loading

(2019) Bryan Ferlez et al.   METABOLIC ENGINEERING

Nanomedicine: An effective tool in cancer therapy

(2018) Saima Aftab et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Bacterial Microcompartment Is Used for Choline Fermentation by Escherichia coli 536

(2018) Taylor I. Herring et al.   JOURNAL OF BACTERIOLOGY

Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli

(2018) Kevin W. George et al.   METABOLIC ENGINEERING

Bacterial microcompartments

(2018) Cheryl A. Kerfeld et al.   NATURE REVIEWS MICROBIOLOGY

Coupled laboratory and field investigations resolve microbial interactions that underpin persistence in hydraulically fractured shales

(2018) Mikayla A. Borton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Applications and perspectives of nanomaterials in novel vaccine development

(2018) Yingbin Shen et al.   MedChemComm

Programmed loading and rapid purification of engineered bacterial microcompartment shells

(2018) Andrew Hagen et al.   Nature Communications

Visualizing Individual RuBisCO and Its Assembly into Carboxysomes in Marine Cyanobacteria by Cryo-Electron Tomography

(2018) Wei Dai et al.   JOURNAL OF MOLECULAR BIOLOGY

Selective Permeability of Carboxysome Shell Pores to Anionic Molecules

(2018) Paween Mahinthichaichan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Carboxysome encapsulation of the CO2-fixing enzyme Rubisco in tobacco chloroplasts

(2018) Benedict M. Long et al.   Nature Communications

De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments

(2018) Matthew J. Lee et al.   Nature Communications

Deciphering molecular details in the assembly of alpha-type carboxysome

(2018) Yilan Liu et al.   Scientific Reports

Characterization Of A Glycyl-Radical Enzyme Bacterial Microcompartment Pathway In Rhodobacter capsulatus

(2018) Heidi S. Schindel et al.   JOURNAL OF BACTERIOLOGY

Structural and kinetic characterization of (S)-1-amino-2-propanol kinase from the aminoacetone utilization microcompartment of Mycobacterium smegmatis

(2018) Evan Mallette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptide-decorated polymeric nanomedicines for precision cancer therapy

(2018) Huanli Sun et al.   JOURNAL OF CONTROLLED RELEASE

In Vitro Assembly of Diverse Bacterial Microcompartment Shell Architectures

(2018) Andrew R. Hagen et al.   NANO LETTERS

Heterohexamers Formed by CcmK3 and CcmK4 Increase the Complexity of Beta Carboxysome Shells

(2018) Manuel Sommer et al.   PLANT PHYSIOLOGY

Cell-free biomanufacturing

(2018) Bradley C Bundy et al.   Current Opinion in Chemical Engineering

Heterologous expression of the Halothiobacillus neapolitanus carboxysomal gene cluster in Corynebacterium glutamicum

(2017) Meike Baumgart et al.   JOURNAL OF BIOTECHNOLOGY

Crystal structures of β-carboxysome shell protein CcmP: ligand binding correlates with the closed or open central pore

(2017) Anna M Larsson et al.   JOURNAL OF EXPERIMENTAL BOTANY

The trajectory of microbial single-cell sequencing

(2017) Tanja Woyke et al.   NATURE METHODS

A bioarchitectonic approach to the modular engineering of metabolism

(2017) Cheryl A. Kerfeld   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

De novo design of signal sequences to localize cargo to the 1,2-propanediol utilization microcompartment

(2017) Christopher M. Jakobson et al.   PROTEIN SCIENCE

Assembly principles and structure of a 6.5-MDa bacterial microcompartment shell

(2017) Markus Sutter et al.   SCIENCE

Evidence for Improved Encapsulated Pathway Behavior in a Bacterial Microcompartment through Shell Protein Engineering

(2017) Marilyn F. Slininger Lee et al.   ACS Synthetic Biology

Bacterial microcompartment-directed polyphosphate kinase promotes stable polyphosphate accumulation in E. coli

(2017) Mingzhi Liang et al.   Biotechnology Journal

Sulfide Generation by Dominant Halanaerobium Microorganisms in Hydraulically Fractured Shales

(2017) Anne E. Booker et al.   mSphere

Transfer and analysis of Salmonella pdu genes in a range of Gram-negative bacteria demonstrate exogenous microcompartment expression across a variety of species

(2017) Laura Graf et al.   Microbial Biotechnology

In Vitro Characterization and Concerted Function of Three Core Enzymes of a Glycyl Radical Enzyme - Associated Bacterial Microcompartment

(2017) Jan Zarzycki et al.   Scientific Reports

Metabolite Damage and Metabolite Damage Control in Plants

(2016) Andrew D. Hanson et al.   Annual Review of Plant Biology

Engineering Cellular Metabolism

(2016) Jens Nielsen et al.   CELL

Assembly, function and evolution of cyanobacterial carboxysomes

(2016) Cheryl A Kerfeld et al.   CURRENT OPINION IN PLANT BIOLOGY

A Complete Structural Inventory of the Mycobacterial Microcompartment Shell Proteins Constrains Models of Global Architecture and Transport

(2016) Evan Mallette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Programmed Ribosomal Frameshifting Mediates Expression of the α-Carboxysome

(2016) Thawatchai Chaijarasphong et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure and Function of a Bacterial Microcompartment Shell Protein Engineered to Bind a [4Fe-4S] Cluster

(2016) Clément Aussignargues et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bacterial microcompartments as metabolic modules for plant synthetic biology

(2016) C. Raul Gonzalez-Esquer et al.   PLANT JOURNAL

Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials

(2016) Joseph M. Caster et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

The Structural Basis of Coenzyme A Recycling in a Bacterial Organelle

(2016) Onur Erbilgin et al.   PLOS BIOLOGY

Metabolic Capability of a Predominant Halanaerobium sp. in Hydraulically Fractured Gas Wells and Its Implication in Pipeline Corrosion

(2016) Renxing Liang et al.   Frontiers in Microbiology

Self-assembling protein nanoparticles in the design of vaccines

(2016) Jacinto López-Sagaseta et al.   Computational and Structural Biotechnology Journal

Synthetic scaffolds for pathway enhancement

(2015) Ka-Hei Siu et al.   CURRENT OPINION IN BIOTECHNOLOGY

Selective molecular transport through the protein shell of a bacterial microcompartment organelle

(2015) Chiranjit Chowdhury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial microcompartments and the modular construction of microbial metabolism

(2015) Cheryl A. Kerfeld et al.   TRENDS IN MICROBIOLOGY

Characterization of a Planctomycetal Organelle: a Novel Bacterial Microcompartment for the Aerobic Degradation of Plant Saccharides

(2014) Onur Erbilgin et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Assembly of Robust Bacterial Microcompartment Shells Using Building Blocks from an Organelle of Unknown Function

(2014) Jonathan K. Lassila et al.   JOURNAL OF MOLECULAR BIOLOGY

Enzyme clustering accelerates processing of intermediates through metabolic channeling

(2014) Michele Castellana et al.   NATURE BIOTECHNOLOGY

β-Carboxysomal proteins assemble into highly organized structures inNicotianachloroplasts

(2014) Myat T. Lin et al.   PLANT JOURNAL

Engineering Bacterial Microcompartment Shells: Chimeric Shell Proteins and Chimeric Carboxysome Shells

(2014) Fei Cai et al.   ACS Synthetic Biology

Solution Structure of a Bacterial Microcompartment Targeting Peptide and Its Application in the Construction of an Ethanol Bioreactor

(2014) Andrew D. Lawrence et al.   ACS Synthetic Biology

A Taxonomy of Bacterial Microcompartment Loci Constructed by a Novel Scoring Method

(2014) Seth D. Axen et al.   PLoS Computational Biology

Biogenesis of a Bacterial Organelle: The Carboxysome Assembly Pathway

(2013) Jeffrey C. Cameron et al.   CELL

The Structure of CcmP, a Tandem Bacterial Microcompartment Domain Protein from the β-Carboxysome, Forms a Subcompartment Within a Microcompartment

(2013) Fei Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functions, Compositions, and Evolution of the Two Types of Carboxysomes: Polyhedral Microcompartments That Facilitate CO2 Fixation in Cyanobacteria and Some Proteobacteria

(2013) B. D. Rae et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Insights into the phylogeny and coding potential of microbial dark matter

(2013) Christian Rinke et al.   NATURE

Two new high-resolution crystal structures of carboxysome pentamer proteins reveal high structural conservation of CcmL orthologs among distantly related cyanobacterial species

(2013) Markus Sutter et al.   PHOTOSYNTHESIS RESEARCH

Involvement of a Bacterial Microcompartment in the Metabolism of Fucose and Rhamnose by Clostridium phytofermentans

(2013) Elsa Petit et al.   PLoS One

Nanoparticle vaccines

(2013) Liang Zhao et al.   VACCINE

Elucidating Essential Role of Conserved Carboxysomal Protein CcmN Reveals Common Feature of Bacterial Microcompartment Assembly

(2012) James N. Kinney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Dodecameric CcmK2 Structure Suggests β-Carboxysomal Shell Facets Have a Double-Layered Organization

(2012) Bożena Samborska et al.   STRUCTURE

Coping with complexity in metabolic engineering

(2012) Joerg Mampel et al.   TRENDS IN BIOTECHNOLOGY

The N-Terminal Region of the Medium Subunit (PduD) Packages Adenosylcobalamin-Dependent Diol Dehydratase (PduCDE) into the Pdu Microcompartment

(2011) C. Fan et al.   JOURNAL OF BACTERIOLOGY

Modularity of a carbon-fixing protein organelle

(2011) W. Bonacci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Microcompartments

(2010) Cheryl A. Kerfeld et al.   Annual Review of Microbiology

Ethanolamine Utilization Contributes to Proliferation ofSalmonella entericaSerovar Typhimurium in Food and in Nematodes

(2010) Shabarinath Srikumar et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enterohaemorrhagic Escherichia coli gains a competitive advantage by using ethanolamine as a nitrogen source in the bovine intestinal content

(2010) Yolande Bertin et al.   ENVIRONMENTAL MICROBIOLOGY

Structural Insight into the Mechanisms of Transport across theSalmonella entericaPdu Microcompartment Shell

(2010) Christopher S. Crowley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of Empty Bacterial Microcompartments, Directed Organelle Protein Incorporation, and Evidence of Filament-Associated Organelle Movement

(2010) Joshua B. Parsons et al.   MOLECULAR CELL

Short N-terminal sequences package proteins into bacterial microcompartments

(2010) C. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biosynthesis of Plant Isoprenoids: Perspectives for Microbial Engineering

(2009) James Kirby et al.   Annual Review of Plant Biology

Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization inClostridium kluyveri

(2009) Dana Heldt et al.   BIOCHEMICAL JOURNAL

Identification and Structural Analysis of a Novel Carboxysome Shell Protein with Implications for Metabolite Transport

(2009) Michael G. Klein et al.   JOURNAL OF MOLECULAR BIOLOGY

Organization, Structure, and Assembly of α-Carboxysomes Determined by Electron Cryotomography of Intact Cells

(2009) Cristina V. Iancu et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of the EutL shell protein of the ethanolamine ammonia lyase microcompartment

(2009) M. Sagermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Application of Functional Genomics to Pathway Optimization for Increased Isoprenoid Production

(2008) L. Kizer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microcompartments for B12-Dependent 1,2-Propanediol Degradation Provide Protection from DNA and Cellular Damage by a Reactive Metabolic Intermediate

(2008) E. M. Sampson et al.   JOURNAL OF BACTERIOLOGY

Biochemical and Structural Insights into Bacterial Organelle Form and Biogenesis

(2008) Joshua B. Parsons et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein-based organelles in bacteria: carboxysomes and related microcompartments

(2008) Todd O. Yeates et al.   NATURE REVIEWS MICROBIOLOGY

Atomic-Level Models of the Bacterial Carboxysome Shell

(2008) S. Tanaka et al.   SCIENCE

Structure of the PduU Shell Protein from the Pdu Microcompartment of Salmonella

(2008) Christopher S. Crowley et al.   STRUCTURE