Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

出版年份 2016 全文链接

标题

作者

关键词

Kelch-like ECH-associated protein 1 (KEAP1), Nuclear factor 2 (erythroid-derived 2-like factor) (NFE2L2 or NRF2), Reactive cysteine residue, Triterpenoid antioxidant inflammation modulator (tpAIM), Synthetic antioxidant inflammation modulator AIM (sAIM), X-ray crystallography

出版物

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Volume 1860, Issue 11, Pages 2537-2552

出版商

Elsevier BV

发表日期

2016-07-29

DOI

10.1016/j.bbagen.2016.07.026

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