Sulfated Glycoaminoglycans and Proteoglycan Syndecan-4 Are Involved in Membrane Fixation of LL-37 and Its Pro-Migratory Effect in Breast Cancer Cells

Roles and Mechanisms of Human Cathelicidin LL-37 in Cancer

(2018) Xi Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Proteoglycans remodeling in cancer: Underlying molecular mechanisms

(2017) Achilleas D. Theocharis et al.   MATRIX BIOLOGY

Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

(2017) Enea Sancho-Vaello et al.   Scientific Reports

LL-37 causes cell death of human nasal epithelial cells, which is inhibited with a synthetic glycosaminoglycan

(2017) Andrew J. Thomas et al.   PLoS One

The human cathelicidin LL-37 — A pore-forming antibacterial peptide and host-cell modulator

(2016) Daniela Xhindoli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Human Host Defense Cathelicidin Peptide LL-37 Enhances the Lipopolysaccharide Uptake by Liver Sinusoidal Endothelial Cells without Cell Activation

(2016) Kaori Suzuki et al.   JOURNAL OF IMMUNOLOGY

Molecular mechanisms of LL-37-induced receptor activation: An overview

(2016) Eddy-Tim Verjans et al.   PEPTIDES

LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity

(2016) Adam Fabisiak et al.   Pharmacological Reports

Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells

(2016) Audrey Gambade et al.   Oncotarget

The Role of Cathelicidin LL-37 in Cancer Development

(2015) Ewelina Piktel et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Lipid rafts, KCa/ClCa/Ca2+ channel complexes and EGFR signaling: Novel targets to reduce tumor development by lipids?

(2015) Maxime Guéguinou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Syndecan-1 and Syndecan-4 Capture Epidermal Growth Factor Receptor Family Members and the α3β1 Integrin Via Binding Sites in Their Ectodomains

(2015) Haiyao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycan-related gene expression signatures in breast cancer subtypes; relation to survival

(2015) Ivan O. Potapenko et al.   Molecular Oncology

Association of heparan sulfate proteoglycans SDC1 and SDC4 polymorphisms with breast cancer in an Australian Caucasian population

(2014) Rachel K. Okolicsanyi et al.   TUMOR BIOLOGY

The Motile Breast Cancer Phenotype Roles of Proteoglycans/Glycosaminoglycans

(2014) Dragana Nikitovic et al.   Biomed Research International

Specific genes involved in synthesis and editing of heparan sulfate proteoglycans show altered expression patterns in breast cancer

(2013) Iván Fernández-Vega et al.   BMC CANCER

Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells

(2013) Anastasios I. Tsonis et al.   FEBS Journal

Syndecan-1 modulates β-integrin-dependent and interleukin-6-dependent functions in breast cancer cell adhesion, migration, and resistance to irradiation

(2013) Hebatallah Hassan et al.   FEBS Journal

Syndecan-4 signaling at a glance

(2013) A. Elfenbein et al.   JOURNAL OF CELL SCIENCE

Heparan Sulfate Proteoglycans and Human Breast Cancer Epithelial Cell Tumorigenicity

(2013) Rachel K. Okolicsanyi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cell surface protein glycosylation in cancer

(2013) Maja N. Christiansen et al.   PROTEOMICS

Xentry, a new class of cell-penetrating peptide uniquely equipped for delivery of drugs

(2013) Kristopher Montrose et al.   Scientific Reports

Features and applications of bacterial sialidases

(2011) Seonghun Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cationic amphipathic peptides accumulate sialylated proteins and lipids in the plasma membrane of eukaryotic host cells

(2011) Julian Weghuber et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Letter to the Glyco-Forum: Effective glycoanalysis with Maackia amurensis lectins requires a clear understanding of their binding specificities

(2011) C. Geisler et al.   GLYCOBIOLOGY

Syndecan-1 and Syndecan-4 Are Independent Indicators in Breast Carcinoma

(2011) Maria E. Lendorf et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Syndecan-1 and -4 differentially regulate oncogenic K-ras dependent cell invasion into collagen through α2β1 integrin and MT1-MMP

(2011) Karoliina Vuoriluoto et al.   MATRIX BIOLOGY

The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium

(2010) Peter G. Barlow et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cell-penetrating peptide exploited syndecans

(2010) Tamás Letoha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Leucine Leucine-37 Uses Formyl Peptide Receptor-Like 1 to Activate Signal Transduction Pathways, Stimulate Oncogenic Gene Expression, and Enhance the Invasiveness of Ovarian Cancer Cells

(2009) S. B. Coffelt et al.   MOLECULAR CANCER RESEARCH

Cholesterol, lanosterol, and ergosterol attenuate the membrane association of LL-37(W27F) and temporin L

(2008) Rohit Sood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Binding of LL-37 to model biomembranes: Insight into target vs host cell recognition

(2008) Rohit Sood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Human Cathelicidin LL-37 Modulates the Activities of the P2X7Receptor in a Structure-dependent Manner

(2008) Linda Tomasinsig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The challenge of lipid rafts

(2008) Linda J. Pike   JOURNAL OF LIPID RESEARCH

Use of a library of mutated Maackia amurensis hemagglutinin for profiling the cell lineage and differentiation

(2008) Keisuke Maenuma et al.   PROTEOMICS

The host defence peptide LL-37/hCAP-18 is a growth factor for lung cancer cells

(2007) Judith von Haussen et al.   LUNG CANCER