ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer
出版年份 2019 全文链接
标题
ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer
作者
关键词
-
出版物
Science Advances
Volume 5, Issue 9, Pages eaax2770
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2019-09-05
DOI
10.1126/sciadv.aax2770
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrin α11 in pancreatic stellate cells regulates tumor stroma interaction in pancreatic cancer
- (2019) Jonas Schnittert et al. FASEB JOURNAL
- Integrins in wound healing, fibrosis and tumor stroma: High potential targets for therapeutics and drug delivery
- (2018) Jonas Schnittert et al. ADVANCED DRUG DELIVERY REVIEWS
- Reprogramming tumor stroma using an endogenous lipid lipoxin A4 to treat pancreatic cancer
- (2018) Jonas Schnittert et al. CANCER LETTERS
- The fibrotic tumor stroma
- (2018) Mitsuo Yamauchi et al. JOURNAL OF CLINICAL INVESTIGATION
- Nano-targeted relaxin impairs fibrosis and tumor growth in pancreatic cancer and improves the efficacy of gemcitabine in vivo
- (2018) Deby F. Mardhian et al. JOURNAL OF CONTROLLED RELEASE
- IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma
- (2018) Giulia Biffi et al. Cancer Discovery
- Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence
- (2017) Janusz Franco-Barraza et al. eLife
- MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor
- (2016) Praneeth R. Kuninty et al. Oncotarget
- The conflicting roles of tumor stroma in pancreatic cancer and their contribution to the failure of clinical trials: a systematic review and critical appraisal
- (2015) Maarten F. Bijlsma et al. CANCER AND METASTASIS REVIEWS
- Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
- (2015) Bruno Costa-Silva et al. NATURE CELL BIOLOGY
- α-Smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study
- (2014) M Sinn et al. BRITISH JOURNAL OF CANCER
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment
- (2013) Minoti V. Apte et al. GASTROENTEROLOGY
- Integrin α5β1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors
- (2013) Florence Schaffner et al. Cancers
- The Pancreas Cancer Microenvironment
- (2012) C. Feig et al. CLINICAL CANCER RESEARCH
- Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells
- (2012) Hongyu Tian et al. EMBO JOURNAL
- Complexities of TGF-β Targeted Cancer Therapy
- (2012) Erin C. Connolly et al. International Journal of Biological Sciences
- Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor
- (2012) Masamichi Nagae et al. JOURNAL OF CELL BIOLOGY
- PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker
- (2012) Sayaka Yuzawa et al. MEDICAL ONCOLOGY
- Selective Targeting of Interferon to Stromal Fibroblasts and Pericytes as a Novel Therapeutic Approach to Inhibit Angiogenesis and Tumor Growth
- (2012) R. Bansal et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of TGF-?1-Induced Pro-Apoptotic Signaling by Growth Factor Receptors and Extracellular Matrix Receptor Integrins in the Liver
- (2011) Iwata Ozaki et al. Frontiers in Physiology
- Breast Cancer Cells in Three-dimensional Culture Display an Enhanced Radioresponse after Coordinate Targeting of Integrin 5 1 and Fibronectin
- (2010) J.-M. Nam et al. CANCER RESEARCH
- Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing
- (2010) Coert Margadant et al. EMBO REPORTS
- Stromal biology and therapy in pancreatic cancer
- (2010) A. Neesse et al. GUT
- Pancreatic Stellate Cells: Partners in Crime with Pancreatic Cancer Cells
- (2008) A. Vonlaufen et al. CANCER RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now