Nucleolin and nucleophosmin: nucleolar proteins with multiple functions in DNA repair

Mismatch repair and homeologous recombination

(2016) Khek-Chian Tham et al.   DNA REPAIR

Base Excision Repair, a Pathway Regulated by Posttranslational Modifications

(2016) Rachel J. Carter et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

(2016) Diana M Mitrea et al.   eLife

The roles of nucleolin subcellular localization in cancer

(2015) Caroline Madeleine Berger et al.   BIOCHIMIE

Facilitation of base excision repair by chromatin remodeling

(2015) John M. Hinz et al.   DNA REPAIR

Nucleolin: Dual roles in rDNA chromatin transcription

(2015) Nathalie Durut et al.   GENE

A Novel Post-translational Modification of Nucleolin, SUMOylation at Lys-294, Mediates Arsenite-induced Cell Death by Regulatinggadd45α mRNA Stability

(2015) Dongyun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mismatch Repair

(2015) Richard Fishel   JOURNAL OF BIOLOGICAL CHEMISTRY

The Pentameric Nucleoplasmin Fold Is Present in Drosophila FKBP39 and a Large Number of Chromatin-Related Proteins

(2015) Christian Edlich-Muth et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties

(2015) Mattia Poletto et al.   MOLECULAR CARCINOGENESIS

An Overview of the Molecular Mechanisms of Recombinational DNA Repair

(2015) Stephen C. Kowalczykowski   Cold Spring Harbor Perspectives in Biology

HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response

(2015) Key-Hwan Lim et al.   Scientific Reports

Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition

(2015) Takashi Onikubo et al.   Cell Reports

The spatial organization of non-homologous end joining: From bridging to end joining

(2014) Takashi Ochi et al.   DNA REPAIR

New insights and challenges in mismatch repair: Getting over the chromatin hurdle

(2014) Guo-Min Li   DNA REPAIR

Roles of chromatin remodellers in DNA double strand break repair

(2014) Penny A. Jeggo et al.   EXPERIMENTAL CELL RESEARCH

Connecting the nucleolus to the cell cycle and human disease

(2014) Robert Y. L. Tsai et al.   FASEB JOURNAL

Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands

(2014) Hirota Fujiki et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins

(2014) Mattia Poletto et al.   MOLECULAR BIOLOGY OF THE CELL

Understanding nucleotide excision repair and its roles in cancer and ageing

(2014) Jurgen A. Marteijn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy

(2014) T-I Hsu et al.   ONCOGENE

Structural polymorphism in the N-terminal oligomerization domain of NPM1

(2014) D. M. Mitrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The prolyl isomerase, FKBP25, interacts with RNA-engaged nucleolin and the pre-60S ribosomal subunit

(2014) G. Gudavicius et al.   RNA

Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin

(2014) Omer Ziv et al.   Nature Communications

An overview of pre-ribosomal RNA processing in eukaryotes

(2014) Anthony K. Henras et al.   Wiley Interdisciplinary Reviews-RNA

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

Emerging Roles of the Nucleolus in Regulating the DNA Damage Response: The Noncanonical DNA Repair Enzyme APE1/Ref-1 as a Paradigmatical Example

(2013) Giulia Antoniali et al.   ANTIOXIDANTS & REDOX SIGNALING

Chromatin dynamics during spermiogenesis

(2013) Christina Rathke et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cytoplasmic ribosomal protein S3 (rpS3) plays a pivotal role in mitochondrial DNA damage surveillance

(2013) YongJoong Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

DNA DSB repair pathway choice: an orchestrated handover mechanism

(2013) A Kakarougkas et al.   BRITISH JOURNAL OF RADIOLOGY

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration

(2013) Tao Lin et al.   HEPATOLOGY

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology

(2013) C Vascotto et al.   ONCOGENE

Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells

(2013) L. Meng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair

(2013) M. Goldstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleophosmin mutations in acute myeloid leukemia: A tale of protein unfolding and mislocalization

(2013) Luca Federici et al.   PROTEIN SCIENCE

An IKKα-Nucleophosmin Axis Utilizes Inflammatory Signaling to Promote Genome Integrity

(2013) Xiaojun Xia et al.   Cell Reports

A new PICTure of nucleolar stress

(2012) Akira Suzuki et al.   CANCER SCIENCE

Vertebrate nucleoplasmin and NASP: egg histone storage proteins with multiple chaperone activities

(2012) Ron M. Finn et al.   FASEB JOURNAL

Histone Displacement during Nucleotide Excision Repair

(2012) Christoffel Dinant et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

(2012) Lisa Lirussi et al.   MOLECULAR BIOLOGY OF THE CELL

The Human Base Excision Repair Enzyme SMUG1 Directly Interacts with DKC1 and Contributes to RNA Quality Control

(2012) Laure Jobert et al.   MOLECULAR CELL

Interaction of nucleolin with ribosomal RNA genes and its role in RNA polymerase I transcription

(2012) Rong Cong et al.   NUCLEIC ACIDS RESEARCH

Function of homo- and hetero-oligomers of human nucleoplasmin/nucleophosmin family proteins NPM1, NPM2 and NPM3 during sperm chromatin remodeling

(2012) M. Okuwaki et al.   NUCLEIC ACIDS RESEARCH

Nucleolin Inhibits G4 Oligonucleotide Unwinding by Werner Helicase

(2012) Fred E. Indig et al.   PLoS One

Nucleolin Participates in DNA Double-Strand Break-Induced Damage Response through MDC1-Dependent Pathway

(2012) Junya Kobayashi et al.   PLoS One

Crystal Structure and Function of Human Nucleoplasmin (Npm2): A Histone Chaperone in Oocytes and Embryos

(2011) Olga Platonova et al.   BIOCHEMISTRY

The Novel Chemical Entity YTR107 Inhibits Recruitment of Nucleophosmin to Sites of DNA Damage, Suppressing Repair of DNA Double-Strand Breaks and Enhancing Radiosensitization

(2011) K. R. Sekhar et al.   CLINICAL CANCER RESEARCH

Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitination

(2011) Purvi Bhatt et al.   FEBS Journal

Nucleolar structure across evolution: The transition between bi- and tricompartmentalized nucleoli lies within the class Reptilia

(2011) Françoise Lamaye et al.   JOURNAL OF STRUCTURAL BIOLOGY

Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation

(2011) Henna M. Moore et al.   MOLECULAR & CELLULAR PROTEOMICS

ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation

(2011) Aruna Battu et al.   NUCLEIC ACIDS RESEARCH

Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases

(2011) E Colombo et al.   ONCOGENE

Chromatin response to DNA double-strand break damage

(2011) Yunhe Bao   Epigenomics

The C-Terminus of Nucleolin Promotes the Formation of the c-MYCG-Quadruplex and Inhibits c-MYCPromoter Activity

(2010) Verónica González et al.   BIOCHEMISTRY

BRCA2 and Nucleophosmin Coregulate Centrosome Amplification and Form a Complex with the Rho Effector Kinase ROCK2

(2010) H.-F. Wang et al.   CANCER RESEARCH

Recruitment of Phosphorylated NPM1 to Sites of DNA Damage through RNF8-Dependent Ubiquitin Conjugates

(2010) A. Koike et al.   CANCER RESEARCH

RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis

(2010) Lin-Yu Lu et al.   DEVELOPMENTAL CELL

Dephosphorylation of Nucleophosmin by PP1β Facilitates pRB Binding and Consequent E2F1-dependent DNA Repair

(2010) Chiao Yun Lin et al.   MOLECULAR BIOLOGY OF THE CELL

The ACF1 Complex Is Required for DNA Double-Strand Break Repair in Human Cells

(2010) Li Lan et al.   MOLECULAR CELL

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions

(2010) Damiano Fantini et al.   NUCLEIC ACIDS RESEARCH

Surface Expressed Nucleolin Is Constantly Induced in Tumor Cells to Mediate Calcium-Dependent Ligand Internalization

(2010) Ara G. Hovanessian et al.   PLoS One

Nucleolar protein B23 has molecular chaperone activities

(2010) Attila Szebeni et al.   PROTEIN SCIENCE

The Nucleolus

(2010) T. Pederson   Cold Spring Harbor Perspectives in Biology

The nucleolus: structure/function relationship in RNA metabolism

(2010) Danièle Hernandez-Verdun et al.   Wiley Interdisciplinary Reviews-RNA

Nucleophosmin Redistribution following Heat Shock: A Role in Heat-Induced Radiosensitization

(2009) R. P. Vanderwaal et al.   CANCER RESEARCH

Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP

(2009) Daniel R. Foltz et al.   CELL

Nucleolar targeting: the hub of the matter

(2009) Edward Emmott et al.   EMBO REPORTS

Identification and Characterization of Nucleolin as a c-mycG-quadruplex-binding Protein

(2009) Verónica González et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mechanism for Histone Chaperoning Activity of Nucleoplasmin: Thermodynamic and Structural Models

(2009) Stefka G. Taneva et al.   JOURNAL OF MOLECULAR BIOLOGY

Eukaryotic Translesion Polymerases and Their Roles and Regulation in DNA Damage Tolerance

(2009) L. S. Waters et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage

(2009) François-Michel Boisvert et al.   MOLECULAR & CELLULAR PROTEOMICS

A Novel Small-Subunit Processome Assembly Intermediate That Contains the U3 snoRNP, Nucleolin, RRP5, and DBP4

(2009) A. J. Turner et al.   MOLECULAR AND CELLULAR BIOLOGY

APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

(2009) C. Vascotto et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT1 deacetylates APE1 and regulates cellular base excision repair

(2009) Tohru Yamamori et al.   NUCLEIC ACIDS RESEARCH

Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53–MDM2 signaling pathway

(2009) C S Busso et al.   ONCOGENE

Chromatin assembly factors Asf1 and CAF-1 have overlapping roles in deactivating the DNA damage checkpoint when DNA repair is complete

(2009) J.-A. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermodynamic Characterization of Nucleoplasmin Unfolding: Interplay between Function and Stability†

(2008) Guillermo Franco et al.   BIOCHEMISTRY

DNA Damage-Dependent Translocation of B23 and p19ARF Is Regulated by the Jun N-Terminal Kinase Pathway

(2008) O. Yogev et al.   CANCER RESEARCH

Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair

(2008) Chin-Chuan Chen et al.   CELL

Nucleophosmin Interacts with HEXIM1 and Regulates RNA Polymerase II Transcription

(2008) Meera Gurumurthy et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of Abasic Endonuclease Activity of Human Ape1 on Alternative Substrates, as Well as Effects of ATP and Sequence Context on AP Site Incision

(2008) Brian R. Berquist et al.   JOURNAL OF MOLECULAR BIOLOGY

Transcription Regulation of the rRNA Gene by a Multifunctional Nucleolar Protein, B23/Nucleophosmin, through Its Histone Chaperone Activity

(2008) K. Murano et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome

(2008) L. B. Maggi et al.   MOLECULAR AND CELLULAR BIOLOGY

NOPdb: Nucleolar Proteome Database--2008 update

(2008) Y. Ahmad et al.   NUCLEIC ACIDS RESEARCH