Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans
出版年份 2019 全文链接
标题
Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans
作者
关键词
-
出版物
eLife
Volume 8, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2019-08-14
DOI
10.7554/elife.49158
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Single-Copy Knock-In Loci for Defined Gene Expression in Caenorhabditis elegans
- (2019) Carlos G. Silva-García et al. G3-Genes Genomes Genetics
- Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity
- (2017) Guillermo López-Lluch MECHANISMS OF AGEING AND DEVELOPMENT
- Salmon provides fast and bias-aware quantification of transcript expression
- (2017) Rob Patro et al. NATURE METHODS
- Deregulation of CRTCs in Aging and Age-Related Disease Risk
- (2017) Caroline C. Escoubas et al. TRENDS IN GENETICS
- Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
- (2017) Snehal N. Chaudhari et al. Nature Communications
- Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster
- (2017) Anil Rana et al. Nature Communications
- Metformin Activates AMPK through the Lysosomal Pathway
- (2016) Chen-Song Zhang et al. Cell Metabolism
- The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging
- (2016) Brian K. Kennedy et al. Cell Metabolism
- Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides
- (2016) Murat Artan et al. GENES & DEVELOPMENT
- C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins
- (2016) Edward N. Anderson et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans
- (2016) Caroline Heintz et al. NATURE
- Mitochondrial Dynamics and Metabolic Regulation
- (2016) Timothy Wai et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension
- (2016) Philip R. McQuary et al. Cell Reports
- Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
- (2016) Alessandro Bitto et al. eLife
- Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal
- (2015) Kristopher Burkewitz et al. CELL
- Promoting Health and Longevity through Diet: From Model Organisms to Humans
- (2015) Luigi Fontana et al. CELL
- mTOR signaling in cellular and organismal energetics
- (2015) Verena Albert et al. CURRENT OPINION IN CELL BIOLOGY
- High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes
- (2015) A. Paix et al. GENETICS
- TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling
- (2014) Céline E. Riera et al. CELL
- AMPK—Sensing Energy while Talking to Other Signaling Pathways
- (2014) D. Grahame Hardie Cell Metabolism
- AMPK at the Nexus of Energetics and Aging
- (2014) Kristopher Burkewitz et al. Cell Metabolism
- AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner
- (2014) Matthew Ulgherait et al. Cell Reports
- DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans
- (2014) Jennifer M. A. Tullet et al. PLoS Genetics
- Late-life rapamycin treatment reverses age-related heart dysfunction
- (2013) James M. Flynn et al. AGING CELL
- Adenosine Nucleotide Biosynthesis and AMPK Regulate Adult Life Span and Mediate the Longevity Benefit of Caloric Restriction in Flies
- (2013) Drew Stenesen et al. Cell Metabolism
- Metformin improves healthspan and lifespan in mice
- (2013) Alejandro Martin-Montalvo et al. Nature Communications
- Rapamycin slows aging in mice
- (2012) John E. Wilkinson et al. AGING CELL
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake
- (2012) Yossi Dagon et al. Cell Metabolism
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
- (2012) Guangchuang Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Large-Scale Screening for Targeted Knockouts in the Caenorhabditis elegans Genome
- (2012) G3-Genes Genomes Genetics
- A Fluorescent Reporter of AMPK Activity and Cellular Energy Stress
- (2011) Peiling Tsou et al. Cell Metabolism
- Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB
- (2011) William Mair et al. NATURE
- During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
- (2011) Ligia C. Gomes et al. NATURE CELL BIOLOGY
- Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
- (2010) Adem Kalender et al. Cell Metabolism
- 3D reconstruction of histological sections: Application to mammary gland tissue
- (2010) Ignacio Arganda-Carreras et al. MICROSCOPY RESEARCH AND TECHNIQUE
- Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
- (2010) Brian Onken et al. PLoS One
- Extending Healthy Life Span--From Yeast to Humans
- (2010) L. Fontana et al. SCIENCE
- Manipulation of Behavioral Decline in Caenorhabditis elegans with the Rag GTPase raga-1
- (2010) Matthew A. Schreiber et al. PLoS Genetics
- Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways inC. elegans
- (2009) Eric L. Greer et al. AGING CELL
- Optimizing Dietary Restriction for Genetic Epistasis Analysis and Gene Discovery in C. elegans
- (2009) William Mair et al. PLoS One
- Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
- (2009) C. Selman et al. SCIENCE
- mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
- (2009) C. Chen et al. Science Signaling
- An RNAi Screen for Mitochondrial Proteins Required to Maintain the Morphology of the Organelle in Caenorhabditis elegans
- (2008) Ryohei Ichishita et al. JOURNAL OF BIOCHEMISTRY
- Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent of ced-9
- (2008) David G. Breckenridge et al. MOLECULAR CELL
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans
- (2008) Sakiko Honjoh et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now