Simulation of calcium signaling in fine astrocytic processes: Effect of spatial properties on spontaneous activity

Gliotransmission: Beyond Black-and-White

(2018) Iaroslav Savtchouk et al.   JOURNAL OF NEUROSCIENCE

Multiple Lines of Evidence Indicate That Gliotransmission Does Not Occur under Physiological Conditions

(2018) Todd A. Fiacco et al.   JOURNAL OF NEUROSCIENCE

Computational Models for Calcium-Mediated Astrocyte Functions

(2018) Tiina Manninen et al.   Frontiers in Computational Neuroscience

Synaptic neuron-astrocyte communication is supported by an order of magnitude analysis of inositol tris-phosphate diffusion at the nanoscale in a model of peri-synaptic astrocyte projection

(2018) Pavel Montes de Oca Balderas et al.   BMC Biophysics

Potassium and sodium microdomains in thin astroglial processes: A computational model study

(2018) Kevin Breslin et al.   PLoS Computational Biology

Disentangling astroglial physiology with a realistic cell model in silico

(2018) Leonid P. Savtchenko et al.   Nature Communications

Inositol 1,4,5-trisphosphate receptor type 2-independent Ca2+ release from the endoplasmic reticulum in astrocytes

(2018) Yohei Okubo et al.   GLIA

Astrocytic IP3Rs: Contribution to Ca2+signalling and hippocampal LTP

(2017) Mark William Sherwood et al.   GLIA

Diverse protocols for correlative super-resolution fluorescence imaging and electron microscopy of chemically fixed samples

(2017) Benjamin G Kopek et al.   Nature Protocols

Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes

(2017) Amit Agarwal et al.   NEURON

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

(2017) Hua Chai et al.   NEURON

Three-dimensional Ca2+imaging advances understanding of astrocyte biology

(2017) Erika Bindocci et al.   SCIENCE

Ca2+ signals initiate at immobile IP3 receptors adjacent to ER-plasma membrane junctions

(2017) Nagendra Babu Thillaiappan et al.   Nature Communications

Reproducibility and Comparability of Computational Models for Astrocyte Calcium Excitability

(2017) Tiina Manninen et al.   Frontiers in Neuroinformatics

Parallel STEPS: Large Scale Stochastic Spatial Reaction-Diffusion Simulation with High Performance Computers

(2017) Weiliang Chen et al.   Frontiers in Neuroinformatics

Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface

(2017) Anne- Cécile Boulay et al.   Cell Discovery

Highly Sensitive Measurement of Inositol 1,4,5-Trisphosphate by Using a New Fluorescent Ligand and Ligand Binding Domain Combination

(2016) Tai Oura et al.   CHEMBIOCHEM

Twenty years of ModelDB and beyond: building essential modeling tools for the future of neuroscience

(2016) Robert A. McDougal et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Particle-Based Multiscale Modeling of Calcium Puff Dynamics

(2016) Ulrich Dobramysl et al.   MULTISCALE MODELING & SIMULATION

Astrocyte calcium signaling: the third wave

(2016) Narges Bazargani et al.   NATURE NEUROSCIENCE

Functional diversity of astrocytes in neural circuit regulation

(2016) Lucile Ben Haim et al.   NATURE REVIEWS NEUROSCIENCE

Emergence of ion channel modal gating from independent subunit kinetics

(2016) Brendan A. Bicknell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER

(2016) J. Nixon-Abell et al.   SCIENCE

Probing the Complexities of Astrocyte Calcium Signaling

(2016) Eiji Shigetomi et al.   TRENDS IN CELL BIOLOGY

Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion

(2015) Caroline Mauvezin et al.   Autophagy

Exact Stochastic Simulation of a Calcium Microdomain Reveals the Impact of Ca2+ Fluctuations on IP3R Gating

(2015) Nicolas Wieder et al.   BIOPHYSICAL JOURNAL

Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues

(2015) Corrado Calì et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Tracing the Evolutionary History of Inositol, 1, 4, 5-Trisphosphate Receptor: Insights from Analyses ofCapsaspora owczarzakiCa2+Release Channel Orthologs

(2015) Kamil J. Alzayady et al.   MOLECULAR BIOLOGY AND EVOLUTION

An astrocyte-dependent mechanism for neuronal rhythmogenesis

(2015) Philippe Morquette et al.   NATURE NEUROSCIENCE

Ca2+ signaling in astrocytes from Ip3r2 −/− mice in brain slices and during startle responses in vivo

(2015) Rahul Srinivasan et al.   NATURE NEUROSCIENCE

Disentangling calcium-driven astrocyte physiology

(2015) Dmitri A. Rusakov   NATURE REVIEWS NEUROSCIENCE

Time-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca2+ in Neurons and Astroglia

(2015) Kaiyu Zheng et al.   NEURON

Single-Molecule Tracking of Inositol Trisphosphate Receptors Reveals Different Motilities and Distributions

(2014) Ian F. Smith et al.   BIOPHYSICAL JOURNAL

Conditions and Constraints for Astrocyte Calcium Signaling in the Hippocampal Mossy Fiber Pathway

(2014) Martin D. Haustein et al.   NEURON

Dissecting tripartite synapses with STED microscopy

(2014) A. Panatier et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Buffer regulation of calcium puff sequences

(2014) Daniel Fraiman et al.   PHYSICAL BIOLOGY

Automated Analysis of Dynamic Ca2+ Signals in Image Sequences

(2014) Michael Francis et al.   Jove-Journal of Visualized Experiments

Subcellular location of astrocytic calcium stores favors extrasynaptic neuron–astrocyte communication

(2013) Ilya Patrushev et al.   CELL CALCIUM

Astrocyte calcium microdomains are inhibited by Bafilomycin A1 and cannot be replicated by low-level Schaffer collateral stimulation in situ

(2013) Min-Yu Sun et al.   CELL CALCIUM

Diffusive spatio-temporal noise in a first-passage time model for intracellular calcium release

(2013) Mark B. Flegg et al.   JOURNAL OF CHEMICAL PHYSICS

Stochastic Calcium Mechanisms Cause Dendritic Calcium Spike Variability

(2013) H. Anwar et al.   JOURNAL OF NEUROSCIENCE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Full-field dual-color 100-nm super-resolution imaging reveals organization and dynamics of mitochondrial and ER networks

(2013) Maia Brunstein et al.   OPTICS EXPRESS

Comparison of Models for IP3 Receptor Kinetics Using Stochastic Simulations

(2013) Katri Hituri et al.   PLoS One

Ca2+ channel nanodomains boost local Ca2+ amplitude

(2013) M. R. Tadross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic clustering of IP3receptors by IP3

(2012) Taufiq Rahman   BIOCHEMICAL SOCIETY TRANSACTIONS

A Kinetic Model for Type I and II IP3R Accounting for Mode Changes

(2012) Ivo Siekmann et al.   BIOPHYSICAL JOURNAL

The Probability of Triggering Calcium Puffs Is Linearly Related to the Number of Inositol Trisphosphate Receptors in a Cluster

(2012) George D. Dickinson et al.   BIOPHYSICAL JOURNAL

STEPS: efficient simulation of stochastic reaction–diffusion models in realistic morphologies

(2012) Iain Hepburn et al.   BMC Systems Biology

Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

(2012) J. Akerboom et al.   JOURNAL OF NEUROSCIENCE

Differential regulation of the InsP3receptor type-1 and -2 single channel properties by InsP3, Ca2+and ATP

(2012) Larry E. Wagner II et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nanodomain Ca2+ of Ca2+ channels detected by a tethered genetically encoded Ca2+ sensor

(2012) Lai Hock Tay et al.   Nature Communications

Two-Color STED Microscopy of Living Synapses Using A Single Laser-Beam Pair

(2011) Jan Tønnesen et al.   BIOPHYSICAL JOURNAL

STED Nanoscopy of Actin Dynamics in Synapses Deep Inside Living Brain Slices

(2011) Nicolai T. Urban et al.   BIOPHYSICAL JOURNAL

Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses

(2011) Aude Panatier et al.   CELL

The Role of agonist-independent conformational transformation (AICT) in IP3 cluster behavior

(2011) Divya Swaminathan et al.   CELL CALCIUM

Astrocyte Calcium Signaling Transforms Cholinergic Modulation to Cortical Plasticity In Vivo

(2011) N. Takata et al.   JOURNAL OF NEUROSCIENCE

Local Ca2+ detection and modulation of synaptic release by astrocytes

(2011) Maria Amalia Di Castro et al.   NATURE NEUROSCIENCE

Calcium Domains around Single and Clustered IP3 Receptors and Their Modulation by Buffers

(2010) S. Rüdiger et al.   BIOPHYSICAL JOURNAL

Superresolution Localization of Single Functional IP3R Channels Utilizing Ca2+ Flux as a Readout

(2010) Steven M. Wiltgen et al.   BIOPHYSICAL JOURNAL

Cytosolic Ca2+ Buffers

(2010) B. Schwaller   Cold Spring Harbor Perspectives in Biology

Calcium Signals Driven by Single Channel Noise

(2010) Alexander Skupin et al.   PLoS Computational Biology

Modeling of the Modulation by Buffers of Ca2+ Release through Clusters of IP3 Receptors

(2009) S. Zeller et al.   BIOPHYSICAL JOURNAL

A Kinetic Model of the Inositol Trisphosphate Receptor Based on Single-Channel Data

(2009) Elan Gin et al.   BIOPHYSICAL JOURNAL

Glutamate regulation of calcium and IP3 oscillating and pulsating dynamics in astrocytes

(2009) Maurizio De Pittà et al.   JOURNAL OF BIOLOGICAL PHYSICS

Reaction-diffusion master equation, diffusion-limited reactions, and singular potentials

(2009) Samuel A. Isaacson et al.   PHYSICAL REVIEW E

Ca2+ Puffs Originate from Preestablished Stable Clusters of Inositol Trisphosphate Receptors

(2009) I. F. Smith et al.   Science Signaling

Tripartite synapses: astrocytes process and control synaptic information

(2009) Gertrudis Perea et al.   TRENDS IN NEUROSCIENCES

STEPS: Modeling and simulating complex reaction-diffusion systems with Python

(2009) Stefan Wils   Frontiers in Neuroinformatics

Sorting Out Astrocyte Physiology from Pharmacology

(2008) Todd A. Fiacco et al.   Annual Review of Pharmacology and Toxicology

Modeling Ca2+ Feedback on a Single Inositol 1,4,5-Trisphosphate Receptor and Its Modulation by Ca2+ Buffers

(2008) Jianwei Shuai et al.   BIOPHYSICAL JOURNAL

LV-pIN-KDEL: a novel lentiviral vector demonstrates the morphology, dynamics and continuity of the endoplasmic reticulum in live neurones

(2008) Vicky C Jones et al.   BMC NEUROSCIENCE

Localization of puff sites adjacent to the plasma membrane: Functional and spatial characterization of Ca2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP3

(2008) Ian F. Smith et al.   CELL CALCIUM

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

How Does Intracellular Ca2+ Oscillate: By Chance or by the Clock?

(2007) Alexander Skupin et al.   BIOPHYSICAL JOURNAL