Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin

Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies

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Physiologically Based Pharmacokinetics Joined With In Vitro–In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology

(2012) A Rostami-Hodjegan   CLINICAL PHARMACOLOGY & THERAPEUTICS

Human Carbonyl Reductases

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Two Nonsynonymous Single Nucleotide Polymorphisms of Human Carbonyl Reductase 1 Demonstrate Reduced in Vitro Metabolism of Daunorubicin and Doxorubicin

(2009) O. S. Bains et al.   DRUG METABOLISM AND DISPOSITION

Identification of the Promoter of Human Carbonyl Reductase 3 (CBR3) and Impact of Common Promoter Polymorphisms on Hepatic CBR3 mRNA Expression

(2009) Jianping Zhang et al.   PHARMACEUTICAL RESEARCH

Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase

(2008) Satoshi Endo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biotransformation of Drugs in Human Skin

(2008) C. K. Svensson   DRUG METABOLISM AND DISPOSITION

Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1

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Permeation and Metabolism of a Novel Ascorbic Acid Derivative, Disodium Isostearyl 2-O-L-Ascorbyl Phosphate, in Human Living Skin Equivalent Models

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