Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation
出版年份 2019 全文链接
标题
Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation
作者
关键词
continuous manufacturing, lipidoids, lipid-polymer hybrid nanoparticles (LPNs), nanomedicine, quality-by-design, siRNA, solid dosage form, spray drying
出版物
PHARMACEUTICAL RESEARCH
Volume 36, Issue 10, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-08-03
DOI
10.1007/s11095-019-2663-y
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery
- (2019) Kaushik Thanki et al. PHARMACEUTICAL RESEARCH
- Lipidoid-polymer hybrid nanoparticles loaded with TNF siRNA suppress inflammation after intra-articular administration in a murine experimental arthritis model
- (2019) Manon A.A. Jansen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Effect of storage temperature on the stability of spray dried bacteriophage powders
- (2018) Sharon S.Y. Leung et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility
- (2018) Jayesh A. Kulkarni et al. Nucleic Acid Therapeutics
- Patisiran: First Global Approval
- (2018) Sheridan M. Hoy DRUGS
- Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying
- (2017) Monica Agnoletti et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Engineering of small interfering RNA-loaded lipidoid-poly( DL -lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach
- (2017) Kaushik Thanki et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Treatment options for moderate-to-very severe chronic obstructive pulmonary disease
- (2016) Mario Cazzola et al. EXPERT OPINION ON PHARMACOTHERAPY
- Spray drying of fenofibrate loaded nanostructured lipid carriers
- (2016) Dengning Xia et al. Asian Journal of Pharmaceutical Sciences
- Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers
- (2015) Alejandro Sosnik et al. ADVANCES IN COLLOID AND INTERFACE SCIENCE
- Nanoembedded Microparticles for Stabilization and Delivery of Drug-Loaded Nanoparticles
- (2015) Adam Bohr et al. CURRENT PHARMACEUTICAL DESIGN
- Quality by Design approach to spray drying processing of crystalline nanosuspensions
- (2014) Sumit Kumar et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Sugars as bulking agents to prevent nano-crystal aggregation during spray or freeze-drying
- (2014) Sumit Kumar et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Influence of excipients on spray-dried powders for inhalation
- (2014) En-Yu Xu et al. POWDER TECHNOLOGY
- The Effect of Moisture on the Flowability of Pharmaceutical Excipients
- (2013) Allison Crouter et al. AAPS PHARMSCITECH
- Engineering of an Inhalable DDA/TDB Liposomal Adjuvant: A Quality-by-Design Approach Towards Optimization of the Spray Drying Process
- (2013) Pall Thor Ingvarsson et al. PHARMACEUTICAL RESEARCH
- A User-Friendly Model for Spray Drying to Aid Pharmaceutical Product Development
- (2013) Niels Grasmeijer et al. PLoS One
- Depósito pulmonar de partículas inhaladas
- (2012) Ana Fernández Tena et al. ARCHIVOS DE BRONCONEUMOLOGIA
- Emerging anti-inflammatory strategies for COPD
- (2012) Mario Cazzola et al. EUROPEAN RESPIRATORY JOURNAL
- Optimisation of spray drying process conditions for sugar nanoporous microparticles (NPMPs) intended for inhalation
- (2011) Maria Inês Amaro et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA
- (2011) Ditte Krohn Jensen et al. JOURNAL OF CONTROLLED RELEASE
- Quality by design approach in the optimization of the spray-drying process
- (2011) Arnaud Baldinger et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Comparison of Polymeric siRNA Nanocarriers in a Murine LPS-Activated Macrophage Cell Line: Gene Silencing, Toxicity and Off-Target Gene Expression
- (2011) Linda B. Jensen et al. PHARMACEUTICAL RESEARCH
- The impact of spray drying outlet temperature on the particle morphology of mannitol
- (2011) Stephan G. Maas et al. POWDER TECHNOLOGY
- Development of a dried influenza whole inactivated virus vaccine for pulmonary immunization
- (2011) Sandrine A.L. Audouy et al. VACCINE
- Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation
- (2009) Ditte Marie Krohn Jensen et al. JOURNAL OF CONTROLLED RELEASE
- Quality by design – Spray drying of insulin intended for inhalation
- (2008) Morten Jonas Maltesen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Studying the mechanism of RNA separations using RNA chromatography and its application in the analysis of ribosomal RNA and RNA:RNA interactions
- (2008) Sakharam P. Waghmare et al. JOURNAL OF CHROMATOGRAPHY A
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
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