A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients

A Review on Clinical Pharmacokinetics, Pharmacodynamics, and pharmacogenomics of natalizumab: A Humanized Anti-α4 Integrin Monoclonal Antibody

(2018) Li Hao et al.   CURRENT DRUG METABOLISM

Improved methods for predicting peptide binding affinity to MHC class II molecules

(2018) Kamilla Kjaergaard Jensen et al.   IMMUNOLOGY

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

(2018) Daniela Latorre et al.   NATURE

Detection and kinetics of persistent neutralizing anti-interferon-beta antibodies in patients with multiple sclerosis. Results from the ABIRISK prospective cohort study

(2018) Poul Erik H. Jensen et al.   JOURNAL OF NEUROIMMUNOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Incidence and risk factors for adalimumab and infliximab anti-drug antibodies in rheumatoid arthritis: A European retrospective multicohort analysis

(2018) Jocelyn Quistrebert et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Neutralizing capacity of monoclonal and polyclonal anti-natalizumab antibodies: The immune response to antibody therapeutics preferentially targets the antigen-binding site

(2017) Karin A. van Schie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rituximab in multiple sclerosis: Frequency and clinical relevance of anti-drug antibodies

(2017) Nicky Dunn et al.   Multiple Sclerosis Journal

Rituximab in multiple sclerosis: Frequency and clinical relevance of anti-drug antibodies

(2017) Nicky Dunn et al.   Multiple Sclerosis Journal

Characterization of CD4 T Cell Epitopes of Infliximab and Rituximab Identified from Healthy Donors

(2017) Moustafa Hamze et al.   Frontiers in Immunology

Clinical practice of analysis of anti-drug antibodies against interferon beta and natalizumab in multiple sclerosis patients in Europe: A descriptive study of test results

(2017) Jenny Link et al.   PLoS One

Occurrence of Anti-Drug Antibodies against Interferon-Beta and Natalizumab in Multiple Sclerosis: A Collaborative Cohort Analysis

(2016) Delphine Bachelet et al.   PLoS One

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data: Table 1.

(2015) Namita T. Gupta et al.   BIOINFORMATICS

Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium

(2015) B. Rup et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunogenicity of infliximab and adalimumab: what is its role in hypersensitivity and modulation of therapeutic efficacy and safety?

(2015) Giuseppe Murdaca et al.   Expert Opinion On Drug Safety

Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes

(2015) Sinu Paul et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

(2015) Michal Bassani-Sternberg et al.   MOLECULAR & CELLULAR PROTEOMICS

How Natalizumab Binds and Antagonizes α4Integrins

(2013) Yamei Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibodies to Interferon beta in Patients with Multiple Sclerosis Receiving CinnoVex, Rebif, and Betaferon

(2013) Nasrin Zare et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Natalizumab Therapy for Multiple Sclerosis

(2013) Jeremy Chataway et al.   Neurotherapeutics

Quantifying selection in high-throughput Immunoglobulin sequencing data sets

(2012) Gur Yaari et al.   NUCLEIC ACIDS RESEARCH

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

The immunogenicity of humanized and fully human antibodies

(2010) Fiona A. Harding et al.   mAbs

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

(2007) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS