标题
Synergistic effects of common schizophrenia risk variants
作者
关键词
-
出版物
NATURE GENETICS
Volume 51, Issue 10, Pages 1475-1485
出版商
Springer Science and Business Media LLC
发表日期
2019-09-24
DOI
10.1038/s41588-019-0497-5
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting
- (2019) Kathryn R. Bowles et al. PLoS One
- Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
- (2019) Laura M. Huckins et al. NATURE GENETICS
- Trans Effects on Gene Expression Can Drive Omnigenic Inheritance
- (2019) Xuanyao Liu et al. CELL
- Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells
- (2019) Eleni P. Mimitou et al. NATURE METHODS
- Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS
- (2018) Amanda Dobbyn et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model
- (2018) Naomi R. Wray et al. CELL
- New considerations for hiPSC-based models of neuropsychiatric disorders
- (2018) Gabriel E. Hoffman et al. MOLECULAR PSYCHIATRY
- Genetic identification of brain cell types underlying schizophrenia
- (2018) Nathan G. Skene et al. NATURE GENETICS
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
- (2018) Antonio F. Pardiñas et al. NATURE GENETICS
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
- (2018) Hilary K. Finucane et al. NATURE GENETICS
- Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
- (2018) Andrew E. Jaffe et al. NATURE NEUROSCIENCE
- Analysis of shared heritability in common disorders of the brain
- (2018) et al. SCIENCE
- Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
- (2018) Michael J. Gandal et al. SCIENCE
- Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network
- (2018) Peilin Jia et al. Translational Psychiatry
- Rapid and efficient induction of functional astrocytes from human pluripotent stem cells
- (2018) Isaac Canals et al. NATURE METHODS
- Schizophrenia-associated rs4702 G allele-specific downregulation of FURIN expression by miR-338-3p reduces BDNF production
- (2018) Yu Hou et al. SCHIZOPHRENIA RESEARCH
- Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks
- (2018) Adam J. Rubin et al. CELL
- Comprehensive functional genomic resource and integrative model for the human brain
- (2018) Daifeng Wang et al. SCIENCE
- Fine-mapping inflammatory bowel disease loci to single-variant resolution
- (2017) Hailiang Huang et al. NATURE
- Assembly of functionally integrated human forebrain spheroids
- (2017) Fikri Birey et al. NATURE
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- Molecular and functional variation in iPSC-derived sensory neurons
- (2017) Jeremy Schwartzentruber et al. NATURE GENETICS
- Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
- (2017) Daniel J Weiner et al. NATURE GENETICS
- Generation of pure GABAergic neurons by transcription factor programming
- (2017) Nan Yang et al. NATURE METHODS
- Closed-Loop Real-Time Imaging Enables Fully Automated Cell-Targeted Patch-Clamp Neural Recording In Vivo
- (2017) Ho-Jun Suk et al. NEURON
- Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains
- (2017) Gabriel E. Hoffman et al. Nature Communications
- Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
- (2017) Atsushi Takata et al. Nature Communications
- Strength of functional signature correlates with effect size in autism
- (2017) Sara Ballouz et al. Genome Medicine
- Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes
- (2017) Seok-Man Ho et al. Stem Cell Reports
- FINEMAP: efficient variable selection using summary data from genome-wide association studies
- (2016) Christian Benner et al. BIOINFORMATICS
- variancePartition: interpreting drivers of variation in complex gene expression studies
- (2016) Gabriel E. Hoffman et al. BMC BIOINFORMATICS
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
- (2016) Atray Dixit et al. CELL
- Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells
- (2016) Seok-Man Ho et al. METHODS
- Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
- (2016) Dominik Paquet et al. NATURE
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion
- (2016) Sungkun Chun et al. NATURE MEDICINE
- Augmenting CRISPR applications in Drosophila with tRNA-flanked sgRNAs
- (2016) Fillip Port et al. NATURE METHODS
- Gene expression elucidates functional impact of polygenic risk for schizophrenia
- (2016) Menachem Fromer et al. NATURE NEUROSCIENCE
- Erratum: Common alleles contribute to schizophrenia in CNV carriers
- (2015) K E Tansey et al. MOLECULAR PSYCHIATRY
- Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
- (2015) Anca M Paşca et al. NATURE METHODS
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
- (2015) NATURE NEUROSCIENCE
- Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci
- (2015) Stephan J. Sanders et al. NEURON
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro
- (2015) Cedric Bardy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A survey of human brain transcriptome diversity at the single cell level
- (2015) Spyros Darmanis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered serine/threonine kinase activity in schizophrenia
- (2014) Jennifer L. McGuire et al. BRAIN RESEARCH
- Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia
- (2014) M Föcking et al. MOLECULAR PSYCHIATRY
- De novo mutations in schizophrenia implicate synaptic networks
- (2014) Menachem Fromer et al. NATURE
- A polygenic burden of rare disruptive mutations in schizophrenia
- (2014) Shaun M. Purcell et al. NATURE
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS
- (2013) Xin He et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
- (2013) Yingsha Zhang et al. NEURON
- Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries
- (2012) Michael E. Talkowski et al. CELL
- Neuroligin-1–dependent competition regulates cortical synaptogenesis and synapse number
- (2012) Hyung-Bae Kwon et al. NATURE NEUROSCIENCE
- Reduction of AP180 and CALM Produces Defects in Synaptic Vesicle Size and Density
- (2012) Ronald S. Petralia et al. NEUROMOLECULAR MEDICINE
- Pharmacogenomics and Personalized Medicine in Neuropsychiatry
- (2012) Francis J. McMahon et al. NEURON
- Camera: a competitive gene set test accounting for inter-gene correlation
- (2012) Di Wu et al. NUCLEIC ACIDS RESEARCH
- The mystery of missing heritability: Genetic interactions create phantom heritability
- (2012) O. Zuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular signatures database (MSigDB) 3.0
- (2011) A. Liberzon et al. BIOINFORMATICS
- A Living Fossil in the Genome of a Living Fossil: Harbinger Transposons in the Coelacanth Genome
- (2011) J. J. Smith et al. MOLECULAR BIOLOGY AND EVOLUTION
- De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
- (2011) G Kirov et al. MOLECULAR PSYCHIATRY
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
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