Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics
出版年份 2019 全文链接
标题
Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics
作者
关键词
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出版物
NATURE BIOTECHNOLOGY
Volume 37, Issue 10, Pages 1149-1154
出版商
Springer Science and Business Media LLC
发表日期
2019-09-10
DOI
10.1038/s41587-019-0241-9
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Minimap2: pairwise alignment for nucleotide sequences
- (2018) Heng Li BIOINFORMATICS
- Recent advances in activating silent biosynthetic gene clusters in bacteria
- (2018) Dainan Mao et al. CURRENT OPINION IN MICROBIOLOGY
- Engineered integrative and conjugative elements for efficient and inducible DNA transfer to undomesticated bacteria
- (2018) Jennifer A. N. Brophy et al. Nature Microbiology
- Activation of silent biosynthetic gene clusters using transcription factor decoys
- (2018) Bin Wang et al. Nature Chemical Biology
- Fast and accurate de novo genome assembly from long uncorrected reads
- (2017) Robert Vaser et al. GENOME RESEARCH
- Detecting DNA cytosine methylation using nanopore sequencing
- (2017) Jared T Simpson et al. NATURE METHODS
- antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification
- (2017) Kai Blin et al. NUCLEIC ACIDS RESEARCH
- Lateral Gene Transfer Dynamics in the Ancient Bacterial Genus Streptomyces
- (2017) Bradon R. McDonald et al. mBio
- Integration of Molecular Networking and In-Silico MS/MS Fragmentation for Natural Products Dereplication
- (2016) Pierre-Marie Allard et al. ANALYTICAL CHEMISTRY
- Minimap and miniasm: fast mapping and de novo assembly for noisy long sequences
- (2016) Heng Li BIOINFORMATICS
- Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
- (2016) Mingxun Wang et al. NATURE BIOTECHNOLOGY
- Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining
- (2015) Xiaoyu Tang et al. ACS Chemical Biology
- Bandage: interactive visualization ofde novogenome assemblies: Fig. 1.
- (2015) Ryan R. Wick et al. BIOINFORMATICS
- Taxonomy, Physiology, and Natural Products of Actinobacteria
- (2015) Essaid Ait Barka et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Discovery of microbial natural products by activation of silent biosynthetic gene clusters
- (2015) Peter J. Rutledge et al. NATURE REVIEWS MICROBIOLOGY
- CRISPR-Cas9 Based Engineering of Actinomycetal Genomes
- (2015) Yaojun Tong et al. ACS Synthetic Biology
- Solving the Antibiotic Crisis
- (2015) Gerard D. Wright ACS Infectious Diseases
- Something old, something new: revisiting natural products in antibiotic drug discovery
- (2014) Gerard D. Wright CANADIAN JOURNAL OF MICROBIOLOGY
- Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters
- (2014) Peter Cimermancic et al. CELL
- High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System
- (2014) Ryan E. Cobb et al. ACS Synthetic Biology
- Integrated Metabolomics Approach Facilitates Discovery of an Unpredicted Natural Product Suite from Streptomyces coelicolor M145
- (2013) Ashley M. Sidebottom et al. ACS Chemical Biology
- JadR*-mediated feed-forward regulation of cofactor supply in jadomycin biosynthesis
- (2013) Yanyan Zhang et al. MOLECULAR MICROBIOLOGY
- Characterization of the Amicetin Biosynthesis Gene Cluster from Streptomyces vinaceusdrappus NRRL 2363 Implicates Two Alternative Strategies for Amide Bond Formation
- (2012) Gaiyun Zhang et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Chemical Perturbation of Secondary Metabolism Demonstrates Important Links to Primary Metabolism
- (2012) Arryn Craney et al. CHEMISTRY & BIOLOGY
- Recover the lost art of drug discovery
- (2012) Kim Lewis NATURE
- A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis
- (2012) Chitose Maruyama et al. Nature Chemical Biology
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Accelerated Profile HMM Searches
- (2011) Sean R. Eddy PLoS Computational Biology
- Search and clustering orders of magnitude faster than BLAST
- (2010) Robert C. Edgar BIOINFORMATICS
- Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster
- (2010) Jette Thykaer et al. METABOLIC ENGINEERING
- FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments
- (2010) Morgan N. Price et al. PLoS One
- Golden Gate Shuffling: A One-Pot DNA Shuffling Method Based on Type IIs Restriction Enzymes
- (2009) Carola Engler et al. PLoS One
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