Systematic mapping of protein‐metabolite interactions in central metabolism of Escherichia coli

Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)

(2019) Rayner M. L. Queiroz et al.   NATURE BIOTECHNOLOGY

Defining the RNA interactome by total RNA‐associated protein purification

(2019) Vadim Shchepachev et al.   Molecular Systems Biology

A Map of Protein-Metabolite Interactions Reveals Principles of Chemical Communication

(2018) Ilaria Piazza et al.   CELL

Few regulatory metabolites coordinate expression of central metabolic genes in Escherichia coli

(2017) Karl Kochanowski et al.   Molecular Systems Biology

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells

(2017) Doris Höglinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP as a biological hydrotrope

(2017) Avinash Patel et al.   SCIENCE

The lost language of the RNA World

(2017) James W. Nelson et al.   Science Signaling

The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization

(2017) Mohammad Tauqeer Alam et al.   Nature Communications

Genome-Scale Architecture of Small Molecule Regulatory Networks and the Fundamental Trade-Off between Regulation and Enzymatic Activity

(2017) Ed Reznik et al.   Cell Reports

The lost language of the RNA World

(2017) James W. Nelson et al.   Science Signaling

Systematic Identification of Protein–Metabolite Interactions in Complex Metabolite Mixtures by Ligand-Detected Nuclear Magnetic Resonance Spectroscopy

(2016) Yaroslav V. Nikolaev et al.   BIOCHEMISTRY

NMRmix: A Tool for the Optimization of Compound Mixtures in 1D 1H NMR Ligand Affinity Screens

(2016) Jaime L. Stark et al.   JOURNAL OF PROTEOME RESEARCH

Metabolite concentrations, fluxes and free energies imply efficient enzyme usage

(2016) Junyoung O Park et al.   Nature Chemical Biology

BRENDA in 2017: new perspectives and new tools in BRENDA

(2016) Sandra Placzek et al.   NUCLEIC ACIDS RESEARCH

The EcoCyc database: reflecting new knowledge aboutEscherichia coliK-12

(2016) Ingrid M. Keseler et al.   NUCLEIC ACIDS RESEARCH

NMR in drug discovery: A practical guide to identification and validation of ligands interacting with biological macromolecules

(2016) Alvar D. Gossert et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Characterizing Protein–Protein Interactions Using Mass Spectrometry: Challenges and Opportunities

(2016) Arne H. Smits et al.   TRENDS IN BIOTECHNOLOGY

How metabolites modulate metabolic flux

(2015) Andre Wegner et al.   CURRENT OPINION IN BIOTECHNOLOGY

Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique

(2015) M. Ariel Geer et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Defining bacterial regulons using ChIP-seq

(2015) Kevin S. Myers et al.   METHODS

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

(2015) Friedrich B M Reinhard et al.   NATURE METHODS

cCMP and cUMP: emerging second messengers

(2015) Roland Seifert   TRENDS IN BIOCHEMICAL SCIENCES

Pseudo-transition Analysis Identifies the Key Regulators of Dynamic Metabolic Adaptations from Steady-State Data

(2015) Luca Gerosa et al.   Cell Systems

Methods for analyzing and quantifying protein–protein interaction

(2014) Syafrizayanti et al.   Expert Review of Proteomics

Coordination of microbial metabolism

(2014) Victor Chubukov et al.   NATURE REVIEWS MICROBIOLOGY

Tracking cancer drugs in living cells by thermal profiling of the proteome

(2014) M. M. Savitski et al.   SCIENCE

Somewhat in control—the role of transcription in regulating microbial metabolic fluxes

(2013) Karl Kochanowski et al.   CURRENT OPINION IN BIOTECHNOLOGY

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

(2013) Jonathan J Hulce et al.   NATURE METHODS

Advances in the study of protein–DNA interaction

(2012) Yu-Hang Cai et al.   AMINO ACIDS

Regulation of Amino Acid, Nucleotide, and Phosphate Metabolism in Saccharomyces cerevisiae

(2012) P. O. Ljungdahl et al.   GENETICS

EcoCyc: fusing model organism databases with systems biology

(2012) Ingrid M. Keseler et al.   NUCLEIC ACIDS RESEARCH

High-Throughput, Accurate Mass Metabolome Profiling of Cellular Extracts by Flow Injection–Time-of-Flight Mass Spectrometry

(2011) Tobias Fuhrer et al.   ANALYTICAL CHEMISTRY

Revealing the Allosterome: Systematic Identification of Metabolite–Protein Interactions

(2011) Thomas Orsak et al.   BIOCHEMISTRY

Regulation and control of metabolic fluxes in microbes

(2011) Luca Gerosa et al.   CURRENT OPINION IN BIOTECHNOLOGY

Transcriptional Regulation inSaccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and Coactivators

(2011) Steven Hahn et al.   GENETICS

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions

(2011) K. G. Roelofs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive In Vivo Metabolite-Protein Interactions Revealed by Large-Scale Systematic Analyses

(2010) Xiyan Li et al.   CELL

A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae

(2010) Oriol Gallego et al.   Molecular Systems Biology

SIMCOMP/SUBCOMP: chemical structure search servers for network analyses

(2010) M. Hattori et al.   NUCLEIC ACIDS RESEARCH

Target identification using drug affinity responsive target stability (DARTS)

(2009) B. Lomenick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perspectives on NMR in drug discovery: a technique comes of age

(2008) Maurizio Pellecchia et al.   NATURE REVIEWS DRUG DISCOVERY