Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR
出版年份 2019 全文链接
标题
Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL MEDICINE
Volume -, Issue -, Pages jem.20190111
出版商
Rockefeller University Press
发表日期
2019-09-27
DOI
10.1084/jem.20190111
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
- (2019) Rebecca C. Coll et al. Nature Chemical Biology
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
- (2018) Charles L. Evavold et al. IMMUNITY
- Targeting the NLRP3 inflammasome in inflammatory diseases
- (2018) Matthew S. J. Mangan et al. NATURE REVIEWS DRUG DISCOVERY
- The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection
- (2018) Hideki Hara et al. CELL
- The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
- (2018) Meihong Deng et al. IMMUNITY
- NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8
- (2017) Isabella Rauch et al. IMMUNITY
- CD36 and Platelet-Activating Factor Receptor Promote House Dust Mite Allergy Development
- (2017) Preeyam S. Patel et al. JOURNAL OF IMMUNOLOGY
- Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells
- (2017) Shu Zhu et al. NATURE
- The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity
- (2017) Katharina S. Schneider et al. Cell Reports
- Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome
- (2016) Chuansheng Guo et al. IMMUNITY
- K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
- (2016) Christina J. Groß et al. IMMUNITY
- NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
- (2016) Yuan He et al. NATURE
- NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations
- (2016) Leanne Mortimer et al. NATURE IMMUNOLOGY
- NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
- (2016) Jong-Seok Moon et al. NATURE MEDICINE
- An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
- (2016) Ivan Zanoni et al. SCIENCE
- A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection
- (2016) Te-Chen Tzeng et al. Cell Reports
- Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome
- (2015) Yiqing Yan et al. CELL
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation
- (2015) Jonathan L. Schmid-Burgk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
- (2015) Hexin Shi et al. NATURE IMMUNOLOGY
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Inflammasomes: mechanism of action, role in disease and therapeutics
- (2015) Haitao Guo et al. NATURE MEDICINE
- Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt
- (2015) Justin E Wilson et al. NATURE MEDICINE
- Nuclear Factor E2-related Factor-2 (Nrf2) Is Required for NLRP3 and AIM2 Inflammasome Activation
- (2014) Changcheng Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammatory caspases are innate immune receptors for intracellular LPS
- (2014) Jianjin Shi et al. NATURE
- Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome
- (2014) Hao Xu et al. NATURE
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation
- (2013) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
- (2013) J. A. Hagar et al. SCIENCE
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
- An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
- (2012) Sonal Khare et al. IMMUNITY
- NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice
- (2012) M. Kovarova et al. JOURNAL OF IMMUNOLOGY
- The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
- (2012) Geun-Shik Lee et al. NATURE
- Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
- (2012) Manuela Rossol et al. Nature Communications
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
- (2011) Eran Elinav et al. CELL
- IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
- (2011) Nagaraj Kerur et al. Cell Host & Microbe
- The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
- (2011) Yue Zhao et al. NATURE
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses
- (2010) Christian C. Yost et al. BIOCHIMIE
- Cryopyrin-Associated Periodic Syndrome: An Update on Diagnosis and Treatment Response
- (2010) Justin R. Yu et al. CURRENT ALLERGY AND ASTHMA REPORTS
- Mouse and Human Eosinophils Degranulate in Response to Platelet-Activating Factor (PAF) and LysoPAF via a PAF-Receptor-Independent Mechanism: Evidence for a Novel Receptor
- (2010) K. D. Dyer et al. JOURNAL OF IMMUNOLOGY
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
- (2009) Tilmann Bürckstümmer et al. NATURE IMMUNOLOGY
- ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1 and IL-18 secretion in an autocrine way
- (2008) A. Piccini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started