MAZ promotes prostate cancer bone metastasis through transcriptionally activating the KRas-dependent RalGEFs pathway

AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis

(2017) Ni Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway

(2017) Dong Ren et al.   Molecular Cancer

Synthetic Lethality in PTEN-Mutant Prostate Cancer Is Induced by Combinatorial PI3K/Akt and BCL-X L Inhibition

(2016) Wenying Ren et al.   MOLECULAR CANCER RESEARCH

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

(2016) Akash Kumar et al.   NATURE MEDICINE

Role for EGFR & HER2 in bone metastasis

(2016) Clemens Thoma   Nature Reviews Urology

XRP44X, an Inhibitor of Ras/Erk Activation of the Transcription Factor Elk3, Inhibits Tumour Growth and Metastasis in Mice

(2016) Kostyantyn Semenchenko et al.   PLoS One

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

(2015) Pierrick G.J. Fournier et al.   CANCER CELL

The Molecular Taxonomy of Primary Prostate Cancer

(2015) Adam Abeshouse et al.   CELL

Bone Metastases and the EGFR and KRAS Mutation Status in Lung Adenocarcinoma - The Results of Three Year Retrospective Analysis

(2015) Nóra Bittner et al.   PATHOLOGY & ONCOLOGY RESEARCH

Novel combination of docetaxel and thymoquinone induces synergistic cytotoxicity and apoptosis in DU-145 human prostate cancer cells by modulating PI3K–AKT pathway

(2014) A. Dirican et al.   Clinical & Translational Oncology

Preclinical Evaluation of Imaging Biomarkers for Prostate Cancer Bone Metastasis and Response to Cabozantinib

(2014) Timothy J. Graham et al.   JNCI-Journal of the National Cancer Institute

RalA signaling pathway as a therapeutic target in hepatocellular carcinoma (HCC)

(2014) Mohamad Ezzeldin et al.   Molecular Oncology

Discovery and characterization of small molecules that target the GTPase Ral

(2014) Chao Yan et al.   NATURE

HRASis silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property

(2014) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH

Induction of Ras by SAF-1/MAZ through a feed-forward loop promotes angiogenesis in breast cancer

(2014) Alpana Ray et al.   Cancer Medicine

The prostate cancer-up-regulated myc-associated zinc-finger protein (MAZ) modulates proliferation and metastasis through reciprocal regulation of androgen receptor

(2013) Li Jiao et al.   MEDICAL ONCOLOGY

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

(2013) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH

Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma

(2012) Michiel Smits et al.   FASEB JOURNAL

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

(2012) Stephan P Tenbaum et al.   NATURE MEDICINE

Notch signalling in cancer progression and bone metastasis

(2011) N Sethi et al.   BRITISH JOURNAL OF CANCER

G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy

(2011) Alexandro Membrino et al.   PLoS One

TheKRASPromoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) Polymerase 1 Proteins, Which Recognize a Critical Quadruplex-formingGA-element

(2010) Susanna Cogoi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TaqMan real-time PCR quantification strategy of CYP2D6 gene copy number for the LightCycler 2.0

(2009) Duc L. Nguyen et al.   CLINICA CHIMICA ACTA

Altered regulation of Prox1-gene-expression in liver tumors

(2008) Jozsef Dudas et al.   BMC CANCER