A novel asymmetrical anti-HER2/CD3 bispecific antibody exhibits potent cytotoxicity for HER2-positive tumor cells
出版年份 2019 全文链接
标题
A novel asymmetrical anti-HER2/CD3 bispecific antibody exhibits potent cytotoxicity for HER2-positive tumor cells
作者
关键词
Bispecific antibody, HER2, CD3, Breast cancer, Knobs-into-holes
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 38, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-08-14
DOI
10.1186/s13046-019-1354-1
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis
- (2018) Qian Liu et al. Journal of Hematology & Oncology
- Recent advances of bispecific antibodies in solid tumors
- (2017) Shengnan Yu et al. Journal of Hematology & Oncology
- The making of bispecific antibodies
- (2017) Ulrich Brinkmann et al. mAbs
- An anti-CD3/anti–CLL-1 bispecific antibody for the treatment of acute myeloid leukemia
- (2016) Steven R. Leong et al. BLOOD
- Bispecific antibodies
- (2015) Roland E. Kontermann et al. DRUG DISCOVERY TODAY
- HER2/neu-directed therapy for biliary tract cancer
- (2015) Milind Javle et al. Journal of Hematology & Oncology
- Blinatumomab: a bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia
- (2015) Jingjing Wu et al. Journal of Hematology & Oncology
- Bispecific antibodies and their applications
- (2015) Gaowei Fan et al. Journal of Hematology & Oncology
- PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo
- (2015) R. Takemura et al. Cancer Immunology Research
- HER2 aberrations in cancer: Implications for therapy
- (2014) Min Yan et al. CANCER TREATMENT REVIEWS
- Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange
- (2013) A. F. Labrijn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair
- (2012) Pavel Strop et al. JOURNAL OF MOLECULAR BIOLOGY
- Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma
- (2011) P. A. Moore et al. BLOOD
- Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
- (2011) W. Schaefer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling
- (2010) Janet Jackman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhancing Antibody Fc Heterodimer Formation through Electrostatic Steering Effects
- (2010) Kannan Gunasekaran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
- (2010) Yung-Jue Bang et al. LANCET
- Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTβR
- (2010) Jennifer S. Michaelson et al. mAbs
- SEEDbodies: fusion proteins based on strand-exchange engineered domain (SEED) CH3 heterodimers in an Fc analogue platform for asymmetric binders or immunofusions and bispecific antibodies†
- (2010) Jonathan H. Davis et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Remodeling domain interfaces to enhance heterodimer formation
- (2010) Zhenping Zhu et al. PROTEIN SCIENCE
- Bispecific T-Cell Engaging Antibodies for Cancer Therapy
- (2009) P. A. Baeuerle et al. CANCER RESEARCH
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