Food-grade titanium dioxide (E171) by solid or liquid matrix administration induces inflammation, germ cells sloughing in seminiferous tubules and blood-testis barrier disruption in mice

In vitro genotoxic effects of titanium dioxide nanoparticles (n-TiO2 ) in human sperm cells

(2019) Marianna Santonastaso et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Determination and identification of titanium dioxide nanoparticles in confectionery foods, marketed in South Korea, using inductively coupled plasma optical emission spectrometry and transmission electron microscopy

(2018) Namhoon Kim et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Titanium dioxide nanoparticles induce human eosinophil adhesion onto endothelial EA.hy926 cells via activation of phosphoinositide 3-kinase/Akt cell signalling pathway

(2018) Maxime Murphy-Marion et al.   IMMUNOBIOLOGY

Suppression of testosterone production by nanoparticulate TiO2 is associated with ERK1/2-PKA-PKC signaling pathways in rat primary cultured Leydig cells

(2018) Lingjuan Li et al.   International Journal of Nanomedicine

Structural and Functional Analysis of the Spermatogenic Epithelium in Rats Exposed to Titanium Dioxide Nanoparticles

(2018) L. A. Sharafutdinova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Comparison of food colour regulations in the EU and the US: a review of current provisions

(2017) Sari Lehto et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Cytoskeletons of Two Reproductive Germ Cell Lines Response Differently to Titanium Dioxide Nanoparticles Mediating Vary Reproductive Toxicity

(2017) Zhilei Mao et al.   Journal of Biomedical Nanotechnology

High sensitivity of testicular function to titanium nanoparticles

(2017) Nobuhiko Miura et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Toxic Effects of Anatase Titanium Dioxide Nanoparticles on Spermatogenesis and Testicles in Male Mice

(2017) Guanling Song et al.   POLISH JOURNAL OF ENVIRONMENTAL STUDIES

Nano-sized titanium dioxide toxicity in rat prostate and testis: Possible ameliorative effect of morin

(2017) Nancy N. Shahin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats

(2017) Clémence Disdier et al.   Scientific Reports

Beneficial effects of quercetin on titanium dioxide nanoparticles induced spermatogenesis defects in mice

(2016) Layasadat Khorsandi et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Food-grade titanium dioxide exposure exacerbates tumor formation in colitis associated cancer model

(2016) Ismael M. Urrutia-Ortega et al.   FOOD AND CHEMICAL TOXICOLOGY

Titanium dioxide food additive (E171) induces ROS formation and genotoxicity: contribution of micro and nano-sized fractions

(2016) Héloïse Proquin et al.   MUTAGENESIS

Oral intake of added titanium dioxide and its nanofraction from food products, food supplements and toothpaste by the Dutch population

(2016) Cathy Rompelberg et al.   Nanotoxicology

A Facile Method for Separating and Enriching Nano and Submicron Particles from Titanium Dioxide Found in Food and Pharmaceutical Products

(2016) James J. Faust et al.   PLoS One

Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43

(2016) Nan Li et al.   Scientific Reports

Anatase titanium dioxide nanoparticles in mice: evidence for induced structural and functional sperm defects after short-, but not long-, term exposure

(2015) PatriciaA Martin-DeLeon et al.   ASIAN JOURNAL OF ANDROLOGY

TiO2 Nanoparticle Exposure Decreases Spermatogenesis via Biochemical Dysfunctions in the Testis of Male Mice

(2015) Fashui Hong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fate of ingested fluids: factors affecting gastric emptying and intestinal absorption of beverages in humans

(2015) John B. Leiper   NUTRITION REVIEWS

Pharmaceutical/food grade titanium dioxide particles are absorbed into the bloodstream of human volunteers

(2015) Laetitia C. Pele et al.   Particle and Fibre Toxicology

Macrophages Contribute to the Spermatogonial Niche in the Adult Testis

(2015) Tony DeFalco et al.   Cell Reports

Protective effect of beta-carotene against titanium dioxide nanoparticles induced apoptosis in mouse testicular tissue

(2014) M. Orazizadeh et al.   ANDROLOGIA

Cytotoxic and Genotoxic Effects of Titanium Dioxide Nanoparticles in Testicular Cells of Male Wistar Rat

(2014) Ramovatar Meena et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Characterization of Titanium Dioxide Nanoparticles in Food Products: Analytical Methods To Define Nanoparticles

(2014) Ruud J. B. Peters et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dispersion Method for Safety Research on Manufactured Nanomaterials

(2013) Wenting WU et al.   INDUSTRIAL HEALTH

Titanium dioxide nanoparticle-induced testicular damage, spermatogenesis suppression, and gene expression alterations in male mice

(2013) Guodong Gao et al.   JOURNAL OF HAZARDOUS MATERIALS

Titanium Dioxide Nanoparticles in Food and Personal Care Products

(2012) Alex Weir et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Immunological, paracrine and endocrine aspects of testicular immune privilege

(2010) Andreas Meinhardt et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Zona Occludens-2 Is Critical for Blood–Testis Barrier Integrity and Male Fertility

(2009) Jianliang Xu et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of human neutrophils by titanium dioxide (TiO2) nanoparticles

(2009) D.M. Gonçalves et al.   TOXICOLOGY IN VITRO